Uveal Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma [Phase 2]
Phase 2 neoadjuvant/adjuvant trial of darovasertib in ocular melanoma has completed enrollment, with St Vincent's Hospital, Sydney listed as…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases [Phase 1]
Phase 1 trial evaluating stereotactic radiosurgery, NovoTTF-200M, and immune checkpoint inhibitors for melanoma brain metastases was termina…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis [Phase 1]
Phase 1 trial evaluating tebentafusp and roginolisib in metastatic uveal melanoma is currently recruiting to study effects on T-cell homeost…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Prospective Registration Of Patient Data and Quality of Life in Eye Melanoma Patients
An observational clinical trial registered to prospectively collect patient data and quality-of-life information in uveal melanoma patients;…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Neoadjuvant Tebentafusp for Uveal Melanoma [Phase 2]
This clinical trial update indicates a Phase 2 neoadjuvant trial of tebentafusp for locally advanced unresectable uveal melanoma is currentl…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Vorinostat in Treating Patients With Metastatic Melanoma of the Eye [Phase 2]
Phase 2 clinical trial update for Vorinostat in metastatic uveal melanoma of the eye. The study is sponsored by the National Cancer Institut…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma [Phase 2]
Phase 2 clinical trial update on the combination of binimetinib and belinostat for metastatic uveal melanoma. The study is currently active …
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma [Phase 1]
Phase 1 clinical trial of targeted alpha particle radiotherapy for metastatic uveal melanoma; the study is currently active but not recruiti…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma [Phase 1]
Phase 1 trial update reports proof of concept for TBio-4101 in combination with lymphodepleting chemotherapy and IL-2 for relapsed/refractor…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma [Phase 2, Phase 3]
A randomized Phase 2/3 trial evaluating RP2 in combination with Nivolumab for metastatic uveal melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease [Phase 1]
Phase 1 study evaluating intravenous and intrathecal nivolumab for leptomeningeal disease in melanoma and non-small cell lung cancer patient…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma [Phase 2]
A Phase 2 clinical trial is evaluating olaparib in combination with pembrolizumab for advanced uveal/ocular melanoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma [Phase 2]
This Phase 2 clinical trial is evaluating a combination of melphalan/HDS delivered via PHP with tebentafusp for metastatic uveal melanoma, w…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers [Phase 1]
Phase 1 trial update for IOA-244, a PI3Kδ inhibitor, being studied in metastatic cancers with status currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma [Phase 1]
Phase 1 neoadjuvant immunotherapy trial for high-risk uveal melanoma has been updated. The study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Psychoeducation for Uveal Melanoma [NA]
A psychoeducation clinical trial for uveal melanoma is currently active but not recruiting, sponsored by the Jonsson Comprehensive Cancer Ce…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Identification of New Candidate Genes for Hereditary Predisposition to Uveal Melanoma [NA]
A clinical trial update describes a study identifying candidate genes that may predispose individuals to hereditary uveal melanoma, with rec…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating a gene-modified immune cell therapy after a conditioning regimen for metastatic melanoma and other metas…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma [Phase 1]
A Phase 1-1b clinical trial is evaluating the safety, preliminary efficacy, and dosimetry of study drug A9-3408 in patients with metastatic …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Sunitinib Malate or Valproic Acid in Preventing Metastasis in Patients With High-Risk Uveal Melanoma [Phase 2]
Phase 2 clinical trial update evaluating sunitinib malate or valproic acid to prevent metastasis in high-risk uveal melanoma.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: (Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma [Phase 2]
Phase 2 trial evaluating darovasertib (IDE196) as neoadjuvant/adjuvant therapy for localized uveal melanoma; the study is currently active b…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver [NA]
A Massachusetts General Hospital-sponsored trial is evaluating the immune response to percutaneous hepatic perfusion with melphalan for live…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases [Phase 1]
This phase 1 study assessed pembrolizumab in combination with stereotactic radiosurgery for patients with brain metastases from melanoma or …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
An ongoing clinical trial is recruiting to study the frequency and clinical phenotype of BAP1 tumor predisposition syndrome and its associat…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Neoadjuvant Tebentafusp in Patients With Metastatic Uveal Melanoma [Phase 2]
A Phase 2 neoadjuvant trial of tebentafusp for metastatic uveal melanoma is currently recruiting.