Uveal Melanoma
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy [Phase 4]
Phase 4 clinical trial comparing TTT alone versus TTT with Triamcinolone to decrease exudation in choroidal/uveal melanoma after proton beam…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Advanced Melanoma [Phase 1]
Phase 1 clinical trial of a melanoma vaccine therapy has completed. The study evaluated safety in patients with advanced melanoma, including…
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase Ib/II study of AEB071 (tavimel) and MEK162 in adult patients with metastatic uveal melanoma was terminated with results posted in 2016…
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT) [Phase 3]
Phase 3 SUMIT trial evaluating selumetinib (AZD6244) in metastatic uveal melanoma has completed, with results posted on 2016-09-28.
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Combined PET/CT Imaging for the Early Detection of Ocular Melanoma Metastasis Compared to CT Scanning Alone
A completed trial comparing combined PET/CT imaging to CT alone for early detection of ocular melanoma metastasis.
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Radiation Therapy in Preventing Liver Metastases in Patients With Uveal Melanoma Who HaveMonosomy 3 or DecisionDx Class 2 Disease and Are More Likely to Develop Liver Metastases [NA]
Clinical trial evaluating radiation therapy to prevent liver metastases in uveal melanoma patients with high risk features; study terminated…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Radioembolization and Ipilimumab in Treating Patients With Uveal Melanoma With Liver Metastases [EARLY_Phase 1]
Early-phase 1 trial evaluating the combination of radioembolization with ipilimumab for uveal melanoma with liver metastases has been termin…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma [Phase 1]
Phase 1 trial evaluating ADI-PEG 20 plus cisplatin in metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Genasense, Carboplatin, Paclitaxel (GCP) Combination in Uveal Melanoma [Phase 2]
Phase 2 study evaluating Genasense (oblimersen) with carboplatin and paclitaxel in uveal melanoma was terminated, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF [Phase 2]
A Phase 2 trial tested halting growth of liver tumors from uveal melanoma by hepatic artery closure after GM-CSF injection; the study has co…
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Treatment With Intravitreal Avastin for Large Uveal Melanomas [NA]
A completed clinical trial update reported results for intravitreal bevacizumab (Avastin) in large uveal melanomas.
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: New Biopsy Technique for Uveal Melanoma
The clinical trial NCT01924923 evaluated a new biopsy technique for uveal melanoma. The study status is COMPLETED.
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma [Phase 2]
A Phase 2 trial of vorinostat in patients with metastatic or unresectable melanoma has completed, with results posted in 2014. The study enc…
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Dendritic Cell Vaccination During Lymphoid Reconstruction [Phase 1]
Phase 1 trial of dendritic cell vaccination during lymphoid reconstruction for uveal melanoma and cutaneous melanoma has completed.
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma [Phase 2]
A Phase 2 trial evaluated a combination of temozolomide, thalidomide, and lomustine in patients with unresectable stage III or IV melanoma, …
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CLINICAL_TRIALS trial_result · 2012-10-30Clinical Trial Update: Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma [Phase 2]
A Phase 2 trial evaluated lenalidomide (Revlimid) for advanced ocular (uveal) melanoma; the study completed and results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Sorafenib, Carboplatin, and Paclitaxel in Treating Patients With Stage IV Melanoma of the Eye [Phase 2]
Phase 2 trial evaluating sorafenib in combination with carboplatin and paclitaxel for stage IV ocular melanoma has completed enrollment, wit…
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CLINICAL_TRIALS trial_result · 2011-06-07Clinical Trial Update: Safety and Immunogenicity of a Melanoma DNA Vaccine Delivered by Electroporation [Phase 1]
A Phase 1 study evaluating the safety and immunogenicity of a melanoma DNA vaccine delivered via electroporation.
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CLINICAL_TRIALS trial_result · 2008-05-09Clinical Trial Update: Tilting of Radioactive Plaques After Initial Accurate Placement for Treatment of Uveal Melanoma [NA]
The document reports an update noting tilting of radioactive plaques after initial placement during treatment of uveal melanoma, which may i…
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CLINICAL_TRIALS trial_result · 2007-10-08Clinical Trial Update: Intravitreal Ranibizumab for the Prevention of Radiation Maculopathy Following Plaque Radiotherapy [Phase 4]
A Phase 4 study evaluating intravitreal ranibizumab to prevent radiation maculopathy after plaque radiotherapy in uveal melanoma, with curre…