Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
A multicenter clinical trial in China is evaluating a urine DNA test for bladder cancer. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update of LYT-200 as a single agent and in combination with chemotherapy or tislelizumab in locally advanced or met…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy [Phase 1]
This is a Phase 1 clinical trial update for TAR-200 in patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based c…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers [Phase 1]
Phase 1 study of cosibelimab (CK-301) as a single-agent therapy in adults with advanced cancers; the trial status is active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer [Phase 1]
A Phase 1 study evaluating the combination of trastuzumab deruxtecan with nivolumab in advanced breast cancer and urothelial carcinoma has c…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CBX-12 in adults with advanced or metastatic refractory solid tumors. The trial includes multiple cancer types and is cur…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Abraxane With Anti-PD1/PDL1 in Patients With Advanced Urothelial Cancer [Phase 2]
Phase 2 trial results update on Abraxane combined with an anti-PD1/PDL1 inhibitor in advanced urothelial carcinoma; the study is completed a…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma
This clinical trial update notes a study analyzing primary and metastatic tumors in patients with renal cell carcinoma and urothelial carcin…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer [Phase 2]
A Phase 2 trial of atezolizumab with bevacizumab in previously untreated metastatic/unresectable urothelial carcinoma was terminated; result…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER) [NA]
The LAYOVER trial evaluating locally ablative therapy for oligoprogressive genitourinary tumors is currently recruiting in prostate cancer, …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell Carcinomas [NA]
A completed clinical trial update examining PSMA expression and PSMA PET imaging in soft tissue sarcomas and urothelial carcinoma.
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CLINICAL_TRIALS withdrawal · 2024-12-09Clinical Trial Update: Vactosertib with Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition [Phase 2]
Phase 2 trial assessing Vactosertib with Durvalumab for urothelial carcinoma that had progressed on checkpoint inhibitors has been withdrawn…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating chidamide in combination with immunotherapy for locally advanced or metastatic urothelial carcinoma. The study is c…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating cabozantinib plus pembrolizumab as first-line therapy for cisplatin-ineligible advanced urothelial carcinoma; resul…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Neutron Radiation Therapy and Pembrolizumab in Treating Participants With Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating neutron radiation therapy with pembrolizumab in advanced urothelial carcinoma; the study is terminated with results…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Phase 2 Clinical Study of ABSK061 and ABSK043 [Phase 2]
Abbisko Therapeutics is recruiting for a Phase 2 study of ABSK061 and ABSK043 in multiple cancers, including HER2-positive gastric/gastroeso…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SHR-A2102 in combination with antitumor therapy is being conducted for advanced urothelial carcinoma and is cu…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Association Between Drug-related Cutaneous Adverse Events and Progression Free Survival in Patients Treated with Enfortumab Vedotin
This clinical trial update evaluates whether enfortumab vedotin–associated cutaneous adverse events correlate with progression-free survival…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
Update on a Phase 3 single-arm trial of UGN-102 for low-grade, intermediate-risk non-muscle invasive bladder cancer; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Current Status of Diagnosis and Treatment of Uroepithelial Carcinoma
A status update for NCT06663735 indicates the urothelial carcinoma trial sponsored by The First Affiliated Hospital of Xinxiang Medical Coll…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study of Enfortumab Vedotin in Japanese Subjects With Locally Advanced or Metastatic Urothelial Carcinoma [Phase 1]
Phase 1 study of enfortumab vedotin in Japanese subjects with locally advanced or metastatic urothelial carcinoma has completed.
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FDA approval · 2024-10-09FDA Approved: BALVERSA — Supplemental Application (Janssen Products LP)
The FDA approved a supplemental application for BALVERSA (erdafitinib) submitted by Janssen Products LP.
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CLINICAL_TRIALS withdrawal · 2024-09-27Clinical Trial Update: Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder) [Phase 2]
This document reports the withdrawal of a Phase 2 trial evaluating avelumab in combination with tuvusertib for advanced urothelial carcinoma…