Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial Carcinoma [Phase 1]
Phase 1b/2 study evaluating Rogaratinib in combination with Atezolizumab in urothelial carcinoma has completed with results posted.
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CLINICAL_TRIALS withdrawal · 2025-04-09Clinical Trial Update: Study of OB-002 in Patients With Refractory Metastatic Cancer [Phase 1]
Phase 1 study of OB-002 in various metastatic cancers has been withdrawn from clinical trials.
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Performance Evaluation of a Urine-based Methylation Assay for Urothelial Carcinoma
This clinical trial update describes the performance evaluation of a urine-based methylation assay for urothelial carcinoma. The study statu…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors [Phase 2, Phase 3]
This clinical trial update notes a modular Phase 2/Phase 3 study of sEphB4-HSA in EphrinB2-high solid tumors, with recruitment ongoing for m…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: ARON-2 Study-Multicentric International Retrospective Study
ARON-2 is a multicenter international retrospective study focusing on urothelial carcinoma, currently recruiting sites/investigators to part…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: A Study to Learn About the Study Medicine (Avelumab) in Japanese Patients With Urothelial Carcinoma That Has Spread
This clinical trial update reports results from a study of Avelumab in Japanese patients with advanced urothelial carcinoma.
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Probiotics in Advanced Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial at Sun Yat-sen University is evaluating probiotics in patients with advanced urothelial carcinoma; the study is cur…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Empa PASS on Urinary Tract Malignancies
Completed post-authorization safety study (PASS) evaluating empagliflozin for urinary tract malignancies with results posted.
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence [Phase 2]
Phase 2 trial evaluating adjuvant sacituzumab govitecan in combination with nivolumab for high-risk, resected muscle-invasive urothelial car…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors [Phase 2]
Phase 2 study evaluating the efficacy of tislelizumab and spartalizumab across multiple cancers with PD-1 high mRNA expression; the trial is…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating 9MW2821 plus toripalimab versus 9MW2821 alone as first-line treatment for locally advanced or metastatic urothelial…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Neoadjuvant Pembrolizumab in Combination With Gemcitabine Therapy in Cis-eligible/Ineligible UC Subjects [Phase 1, Phase 2]
A completed Phase 1/2 neoadjuvant trial evaluating pembrolizumab in combination with gemcitabine for cis-eligible and cis-ineligible urothel…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial evaluating SL-279252, a PD-1-Fc-OX40L fusion protein, in adults with advanced solid tumors or lymphomas has been completed wit…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Study of INCB086550 in Select Solid Tumors [Phase 2]
A Phase 2 trial evaluating INCB086550 across select solid tumors, including non-small cell lung cancer and urothelial carcinoma, was termina…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Multicenter Cancer Biospecimen Collection Study
A multicenter cancer biospecimen collection trial sponsored by Cofactor Genomics is currently recruiting, covering multiple cancer indicatio…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: An Umbrella Study to Determine the Safety and Efficacy of Various Monotherapy or Combination Therapies in Neoadjuvant Urothelial Carcinoma [Phase 2]
An umbrella Phase 2 trial evaluating multiple monotherapy and combination therapies in neoadjuvant urothelial carcinoma was terminated, and …
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Improve Checkpoint-blockade Response in Advanced Urothelial Cancer [Phase 1, Phase 2]
This entry reports the completion of a Phase 1/2 clinical trial investigating strategies to improve response to checkpoint inhibitors in adv…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Pre-operative Immunotherapy in Stage II-III Urothelial Cancer [Phase 1]
Phase 1 study evaluating pre-operative immunotherapy for stage II-III urothelial carcinoma; status is completed.
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Neo-Adjuvant Bladder Urothelial Carcinoma COmbination-immunotherapy [Phase 1]
A completed Phase 1 trial evaluating neo-adjuvant combination immunotherapy in urothelial carcinoma of the bladder.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Named Patient Program for Mitomycin for Pyelocalyceal Solution
This clinical-trials.gov update describes a named patient program for mitomycin-C delivered as a pyelocalyceal solution to treat urothelial …
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FDA approval · 2025-02-27FDA Approved: PADCEV EJFV — Supplemental Application (SEAGEN INC.)
The FDA has approved a supplemental application for PADCEV EJFV (enfortumab vedotin) from Seagen, marking regulatory action on a supplementa…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma [Phase 2]
A Phase 2 trial of intermittent checkpoint inhibitor therapy for advanced urothelial carcinoma was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: A Clinical Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma. [Phase 3]
A Phase 3 study evaluating tislelizumab in combination with cisplatin and gemcitabine, with or without trilaciclib, for untreated unresectab…
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CLINICAL_TRIALS withdrawal · 2025-02-21Clinical Trial Update: QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy [Phase 1, Phase 2]
A Phase 1/2 trial of the NANT Urothelial Cancer Vaccine for urothelial carcinoma in patients who progressed after chemotherapy and PD-1/PD-L…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…