Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC) [Phase 3]
Phase 3 trial update evaluating feasibility of at-home instillation of UGN-102 for low-grade non-muscle invasive bladder cancer. Results wer…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: 9MW2821 in Combination With Toripalimab vs Standard Chemotherapy in Locally Advanced or Metastatic Urothelial Cancer [Phase 3]
A Phase 3 clinical trial evaluating 9MW2821 in combination with toripalimab versus standard chemotherapy for locally advanced or metastatic …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: 9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial Cancer [Phase 1, Phase 2]
This update covers a Phase 1/2 clinical trial of 9MW2821 in combination with toripalimab for advanced urothelial carcinoma. The study is cur…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease [Phase 2]
Phase 2 clinical trial exploring immunotherapy combined with carbon ion radiotherapy in solid cancers with stable disease, currently recruit…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: The Efficacy of the IUrisure for Detection of Recurrent Urothelial Carcinoma
An update on a clinical trial evaluating the efficacy of IUrisure for detecting recurrent urothelial carcinoma; the current status of the tr…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors [Phase 1]
RemeGen's RC198 is being evaluated in a Phase 1 study across locally advanced unresectable or metastatic solid tumors, including melanoma, u…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor [Phase 2]
Phase 2 clinical trial update on pemigatinib plus an immune checkpoint inhibitor for FGFR1/2/3-altered advanced solid tumors; the study is n…
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CLINICAL_TRIALS withdrawal · 2024-08-01Clinical Trial Update: Phase II Trial of Lurbinectedin Combined With Avelumab as Switch Maintenance Firstline Therapy [Phase 2]
This Phase II trial of lurbinectedin plus avelumab as switch-maintenance first-line therapy for metastatic urothelial carcinoma has been wit…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Trial of Stereotactic Body Radiotherapy With Concurrent Pembrolizumab in Metastatic Urothelial Cancer [Phase 1]
A Phase 1 trial assessing stereotactic body radiotherapy with concurrent pembrolizumab for metastatic urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) [Phase 1]
This update reports the completion of a Phase 1 study (DUET-3) evaluating XmAb23104 in patients with selected advanced solid tumors.
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CLINICAL_TRIALS withdrawal · 2024-07-05Clinical Trial Update: Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma [Phase 1]
A Phase 1 study of magrolimab in combination with cytotoxic chemotherapy for advanced urothelial carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
This clinical trial evaluates a urine DNA methylation test for detecting urothelial carcinoma in patients with hematuria.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Trial of Tremelimumab in Patients With Previously Treated Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial of tremelimumab in previously treated metastatic urothelial cancer has completed and results have been posted.
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Urine DNA Methylation Detection for Hematuria Evaluation
ClinicalTrials.gov entry for a study evaluating urine DNA methylation as a noninvasive test to evaluate hematuria and screen for urothelial …
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer [Phase 3]
A Phase 3 study of UGN-102 for low-grade intermediate-risk non-muscle invasive bladder cancer was terminated, with results posted on 2024-06…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study of Pembrolizumab+ sEphB4 in Metastatic Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab in combination with sEphB4 for metastatic urothelial carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer [Phase 1]
Phase 1 study of KHK2455 (IDO inhibitor) plus Avelumab in adults with advanced urothelial carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial of DSP-7888 Dosing Emulsion in combination with immune checkpoint inhibitors in adults with advanced solid tumors was termin…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract [Phase 3]
Phase 3 trial of atezolizumab in locally advanced or metastatic urothelial or non-urothelial carcinoma of the urinary tract has completed wi…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: A Study of TAS-120 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of futibatinib (TAS-120) in patients with advanced solid tumors, including cholangiocarcinoma, urothelial carcinoma, breas…
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CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: Checkpoint Inhibition and Chemoradiotherapy as Bladder Sparing Treatment in UC [Phase 2]
Phase 2 trial evaluating checkpoint inhibition with chemoradiotherapy as a bladder-sparing approach for urothelial carcinoma of the bladder.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A safety and tolerability study of NC318 in advanced or metastatic solid tumors completed Phase 1/2 with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma [Phase 2]
This Phase 2 trial evaluating NIR178 in combination with PDR001 across multiple solid tumors and non-Hodgkin lymphoma was terminated, with r…