Upper Tract Urothelial Carcinoma
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Recalling the Treatment and Prognosis of Upper Tract Urothelial Cancer (UTUC)
A completed clinical trial update from Taipei Tzu Chi Hospital assessing treatment and prognosis for upper tract urothelial carcinoma. The r…
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations [Phase 3]
Phase 3 trial of oral infigratinib as adjuvant treatment for invasive urothelial carcinoma with FGFR3 alterations has been terminated; resul…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating feasibility of neo-adjuvant versus adjuvant chemotherapy for upper tract urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC [Phase 2]
A Phase 2 trial compared neoadjuvant chemotherapy to surgery alone in patients with high-grade upper tract urothelial carcinoma, completed.
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FDA approval · 2022-09-25FDA Approved: JELMYTO — Supplemental Application (UroGen Pharma, Inc.)
FDA approved a supplemental application for JELMYTO (mitomycin) by UroGen Pharma, Inc. The approval updates the product labeling and/or indi…
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Neoadjuvant Treatment of Upper Urinary and Muscular Invasive Bladder Urothelial Carcinoma [Phase 2]
Phase 2 neoadjuvant trial in upper urinary tract urothelial carcinoma and muscle-invasive bladder cancer; status not provided.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer [Phase 3]
Phase 3 trial evaluating adjuvant nivolumab vs placebo after surgical resection for bladder cancer and upper tract urothelial carcinoma, wit…
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer [Phase 2]
Phase 2 trial evaluating chemotherapy before surgery for high-grade upper tract urothelial carcinoma has completed with results posted.
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FDA approval · 2021-01-14FDA Approved: JELMYTO — Supplemental Application (UroGen Pharma, Inc.)
FDA approved a supplemental application for JELMYTO (mitomycin) by UroGen Pharma, Inc.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2 trial updating neoadjuvant PD-1 monoclonal antibody plus cisplatin-based chemotherapy for locally advanced upper tract urothelial ca…
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: Single Versus Long-term Intravesical Instillation Chemotherapy for Recurrence After Nephroureterectomy for Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial comparing single versus long-term intravesical chemotherapy to prevent recurrence after nephroureterectomy for uppe…
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Prophylactic Intravesical Chemotherapy After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Randomized Controlled Trial Between Single Postoperative Dose Versus Maintenance Therapy. [Phase 2]
Phase 2 randomized trial comparing a single postoperative dose versus maintenance intravesical chemotherapy after radical nephroureterectomy…
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CLINICAL_TRIALS research · 2018-05-22Clinical Trial Update: Prognostic Value of Lymph Node Dissection in Patients With Transitional Cell Carcinoma of the Upper Urinary Tract [Phase 2]
This document provides an update on a Phase 2 trial evaluating whether lymph node dissection has prognostic value in patients with upper tra…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Pembrolizumab in Combination With BCG After Ablation in Patients With UUTTCC Without Nephroureterectomy [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with BCG after ablation for high-risk upper tract urothelial carcinoma without nephrou…
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CLINICAL_TRIALS trial_result · 2017-09-21Clinical Trial Update: Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients [Phase 2]
Phase 2 clinical trial evaluating prophylactic intravesical chemotherapy to prevent bladder recurrence after diagnostic ureteroscopy in pati…
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma) [NA]
Clinical trial update on lymph node dissection for high-risk upper tract urothelial carcinoma; current status is unknown.
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy [Phase 3]
Phase 3 trial evaluating pemetrexed maintenance therapy in patients with urothelial carcinoma who completed first-line platinum-based chemot…
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CLINICAL_TRIALS research · 2016-11-17Clinical Trial Update: Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Nephroureterectomy for Primary Upper Tract Urothelial Carcinoma Patients [Phase 2]
Phase 2 clinical trial evaluating prophylactic intravesical chemotherapy to prevent bladder recurrence after nephroureterectomy for primary …
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CLINICAL_TRIALS withdrawal · 2016-10-20Clinical Trial Update: Optical Coherence Tomography in Staging Patients With Upper Tract Urothelial Cancer [NA]
The clinical trial evaluating optical coherence tomography for staging upper tract urothelial carcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Phase I Study of Percutaneous Valrubicin for Upper Tract Urothelial Carcinoma [Phase 1]
Phase I study of percutaneous valrubicin for upper tract urothelial carcinoma has completed its Phase I evaluation. The trial status is COMP…
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CLINICAL_TRIALS research · 2015-09-11Clinical Trial Update: Prophylactic Intravesical Chemotherapy to Prevent Bladder Tumors After Nephroureterectomy for Primary Upper Urinary Tract Urothelial Carcinomas [Phase 2]
Phase 2 clinical trial evaluating prophylactic intravesical chemotherapy to prevent bladder tumor recurrence after nephroureterectomy for pr…
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CLINICAL_TRIALS withdrawal · 2012-02-17Clinical Trial Update: Neoadjuvant Chemotherapy Plus Nephroureterectomy for Locally Advanced Upper Tract Transitional Cell Cancer [Phase 2]
A Phase 2 trial of neoadjuvant chemotherapy plus nephroureterectomy for locally advanced upper tract urothelial carcinoma has been withdrawn…