Upper Tract Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma [Phase 1]
Phase 1 clinical trial evaluating dual-target Nectin-4/HER2 CAR-NK cells for advanced urothelial carcinomas, including bladder cancer, is cu…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating nadofaragene firadenovec delivered to the renal pelvis for low-grade upper tract urothelial carcinoma …
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors [NA]
A completed clinical trial from Lille Catholic University evaluated the diagnostic relevance of laser confocal microscopy for screening uppe…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)] [Phase 2]
This clinical trial update describes a Phase 2 study evaluating pembrolizumab plus Bacillus Calmette-Guérin as first-line therapy for high-r…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating gemcitabine and cisplatin as neoadjuvant chemotherapy for high-grade upper tract urothelial carcinoma has complet…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Treatment of Tumors in the Urinary Collecting System of the Kidney or Ureter Using a Light Activated Drug (WST11) [Phase 1]
Phase 1 study evaluating a light-activated drug (WST11) for treating tumors in the urinary collecting system of the kidney or ureter has com…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Intraoperative vs. Postoperative Intravesical Epirubicin Instillation for Prevention of Bladder Recurrence in High-Risk Upper Urinary Tract Urothelial Carcinoma
A completed clinical trial comparing intraoperative versus postoperative intravesical epirubicin to prevent bladder recurrence in high-risk …
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer. [Phase 4]
Phase 4 clinical trial evaluating how DDR gene alterations influence response to platinum-based chemotherapy in advanced urothelial cancers.…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating Infigratinib before surgery for upper tract urothelial carcinoma has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC
Clinical trial comparing postoperative adjuvant immunotherapy plus radiotherapy versus surgery alone in locally advanced upper tract urothel…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Recalling the Treatment and Prognosis of Upper Tract Urothelial Cancer (UTUC)
A completed clinical trial update from Taipei Tzu Chi Hospital assessing treatment and prognosis for upper tract urothelial carcinoma. The r…
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations [Phase 3]
Phase 3 trial of oral infigratinib as adjuvant treatment for invasive urothelial carcinoma with FGFR3 alterations has been terminated; resul…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating feasibility of neo-adjuvant versus adjuvant chemotherapy for upper tract urothelial carcinoma.
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC [Phase 2]
A Phase 2 trial compared neoadjuvant chemotherapy to surgery alone in patients with high-grade upper tract urothelial carcinoma, completed.
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Neoadjuvant Treatment of Upper Urinary and Muscular Invasive Bladder Urothelial Carcinoma [Phase 2]
Phase 2 neoadjuvant trial in upper urinary tract urothelial carcinoma and muscle-invasive bladder cancer; status not provided.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer [Phase 3]
Phase 3 trial evaluating adjuvant nivolumab vs placebo after surgical resection for bladder cancer and upper tract urothelial carcinoma, wit…
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer [Phase 2]
Phase 2 trial evaluating chemotherapy before surgery for high-grade upper tract urothelial carcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2 trial updating neoadjuvant PD-1 monoclonal antibody plus cisplatin-based chemotherapy for locally advanced upper tract urothelial ca…
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: Single Versus Long-term Intravesical Instillation Chemotherapy for Recurrence After Nephroureterectomy for Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial comparing single versus long-term intravesical chemotherapy to prevent recurrence after nephroureterectomy for uppe…
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Prophylactic Intravesical Chemotherapy After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Randomized Controlled Trial Between Single Postoperative Dose Versus Maintenance Therapy. [Phase 2]
Phase 2 randomized trial comparing a single postoperative dose versus maintenance intravesical chemotherapy after radical nephroureterectomy…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Pembrolizumab in Combination With BCG After Ablation in Patients With UUTTCC Without Nephroureterectomy [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with BCG after ablation for high-risk upper tract urothelial carcinoma without nephrou…
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CLINICAL_TRIALS trial_result · 2017-09-21Clinical Trial Update: Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients [Phase 2]
Phase 2 clinical trial evaluating prophylactic intravesical chemotherapy to prevent bladder recurrence after diagnostic ureteroscopy in pati…
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma) [NA]
Clinical trial update on lymph node dissection for high-risk upper tract urothelial carcinoma; current status is unknown.
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy [Phase 3]
Phase 3 trial evaluating pemetrexed maintenance therapy in patients with urothelial carcinoma who completed first-line platinum-based chemot…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Phase I Study of Percutaneous Valrubicin for Upper Tract Urothelial Carcinoma [Phase 1]
Phase I study of percutaneous valrubicin for upper tract urothelial carcinoma has completed its Phase I evaluation. The trial status is COMP…