Upper Tract Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Ambulatory Flexible URS for UTUC Surveillance [Phase 1]
Phase 1 clinical trial in Hong Kong assessing ambulatory flexible ureteroscopy for surveillance of upper tract urothelial carcinoma; recruit…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma [Phase 2, Phase 3]
A multicenter clinical trial evaluating the ST-02 therapy for ablation of upper tract urothelial carcinoma (renal pelvis and ureter) is curr…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma [NA]
This clinical trial is evaluating nephroureterectomy with and without lymph node dissection for upper tract urothelial carcinoma and is curr…
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CLINICAL_TRIALS other · 2025-09-04Clinical Trial Update: A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
The trial compares neoadjuvant chemotherapy against upfront radical surgery for upper tract urothelial carcinoma and is currently active but…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Neoadjuvant Tislelizumab in Combination With Nab-Paclitaxel for UTUC [Phase 2]
Phase 2 neoadjuvant trial evaluating the PD-1 inhibitor tislelizumab in combination with nab-paclitaxel for upper tract urothelial carcinoma…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating gemcitabine and cisplatin as neoadjuvant chemotherapy for high-grade upper tract urothelial carcinoma has complet…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating the combination of enfortumab vedotin and pembrolizumab for cisplatin-eligible upper tract urothel…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Treatment of Tumors in the Urinary Collecting System of the Kidney or Ureter Using a Light Activated Drug (WST11) [Phase 1]
Phase 1 study evaluating a light-activated drug (WST11) for treating tumors in the urinary collecting system of the kidney or ureter has com…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma [Phase 3]
A Phase 3 clinical trial is currently recruiting to compare gemcitabine against water irrigation for upper tract urothelial carcinoma, inclu…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Goal-directed Hemodynamic Management and Kidney Injury After Radical Nephrectomy or Nephroureterectomy [NA]
This clinical trial update describes a study evaluating goal-directed hemodynamic management to reduce kidney injury following radical nephr…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Whole-slide Image and CT Radiomics Based Deep Learning System for Prognostication Prediction in Upper Tract Urothelial Carcinoma
This clinical trial investigates a deep learning prognostication system that combines whole-slide pathology images and CT radiomics to predi…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)
Recruitment is ongoing for a multicenter prospective cohort study evaluating urinary microscopic residual disease as a method to monitor rec…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Single-Port RAS Using Da Vinci SP Surgical System for UTUC Patients [NA]
This document reports a clinical trial evaluating single-port robotic-assisted surgery using the Da Vinci SP system for upper tract urotheli…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Intraoperative vs. Postoperative Intravesical Epirubicin Instillation for Prevention of Bladder Recurrence in High-Risk Upper Urinary Tract Urothelial Carcinoma
A completed clinical trial comparing intraoperative versus postoperative intravesical epirubicin to prevent bladder recurrence in high-risk …
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Neoadjuvant Chemotherapy in High - Risk Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating neoadjuvant chemotherapy for high-risk upper tract urothelial carcinoma; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
A registry update for the uTRACT Jelmyto Registry, documenting UTUC patients treated with Jelmyto and the study status as Recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer. [Phase 4]
Phase 4 clinical trial evaluating how DDR gene alterations influence response to platinum-based chemotherapy in advanced urothelial cancers.…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively:A Perspective Cohort Study
This document outlines a planned perspective cohort study evaluating the HEFTME System to guide adjuvant therapy selection after surgery for…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: A Study of RC48-ADC Combined with JS001 for Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating RC48-ADC in combination with JS001 as postoperative adjuvant therapy for upper tract urothelial carcinom…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating Infigratinib before surgery for upper tract urothelial carcinoma has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC
Clinical trial comparing postoperative adjuvant immunotherapy plus radiotherapy versus surgery alone in locally advanced upper tract urothel…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Radical Radiotherapy Versus Radical Surgery for UTUC
A clinical trial comparing radical radiotherapy versus radical surgery in upper tract urothelial carcinoma (renal pelvis cancer) is currentl…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs [NA]
A recruiting clinical trial from Peking University First Hospital compares radiotherapy added to systemic therapy versus systemic therapy al…
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FDA approval · 2024-10-04FDA Approved: JELMYTO — Supplemental Application (UroGen Pharma, Inc.)
FDA approves a supplemental application for Jelmyto (mitomycin) submitted by UroGen Pharma, Inc.
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Neoadjuvant Radiotherapy for High-risk UTUC
The update describes a clinical trial evaluating neoadjuvant radiotherapy for high-risk upper tract urothelial carcinoma (renal pelvis and u…