Undifferentiated Pleomorphic Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg [Phase 2]
Phase 2 trial evaluating pembrolizumab plus local chemotherapy delivered by isolated limb infusion for patients with sarcoma in the arm or l…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas [Phase 3]
This Phase 3 trial is evaluating whether adding immunotherapy to chemotherapy improves outcomes versus chemotherapy alone in patients with a…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update describes testing the combination of ipilimumab and nivolumab with or without cabozantinib in adults with ad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery [Phase 2]
Clinical trial update for a Phase 2 study evaluating Talimogene laherparepvec with radiation therapy in newly diagnosed soft tissue sarcoma …
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma [Phase 1]
Phase 1 trial evaluating nivolumab plus BO-112 as a neoadjuvant treatment before surgery for resectable soft tissue sarcoma, including multi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas [NA]
Investigates regorafenib as maintenance therapy after first-line treatment in patients with bone sarcomas and related subtypes. The trial is…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma [Phase 1]
This Phase 1 study evaluates LN-144 or LN-145 in people with advanced uveal melanoma, undifferentiated pleomorphic sarcoma, dedifferentiated…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. [Phase 2]
Clinical trial evaluating dose-escalated, hypofractionated definitive proton radiotherapy for patients with inoperable soft tissue sarcoma (…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating hypofractionated, 3-week preoperative radiotherapy using proton or photon therapy for localized sof…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]
Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ong…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors [Phase 1]
Phase 1 first-in-human trial evaluating OKN4395 in combination with pembrolizumab in patients with solid tumors is currently recruiting. The…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma [NA]
An update on an ongoing clinical trial investigating focused ultrasound to promote immune responses in undifferentiated pleomorphic sarcoma,…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating MASCT-I in combination with doxorubicin and ifosfamide as first-line therapy for advanced soft tissue sarcoma is …
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma [Phase 2]
This is a Phase 2 clinical trial update for envafolimab, administered alone or with ipilimumab, in patients with undifferentiated pleomorphi…