Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: Latent Tuberculosis Infection in Bone Marrow Transplant Recipients
A completed clinical trial update investigating latent tuberculosis infection in recipients of bone marrow transplants, reported by Asan Med…
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CLINICAL_TRIALS trial_result · 2013-07-17Clinical Trial Update: Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis [Phase 2]
Phase 2 study evaluating the efficacy and safety of two raltegravir dosing regimens in ART-naive HIV-1 infected patients receiving rifampin …
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CLINICAL_TRIALS trial_result · 2013-07-17Clinical Trial Update: Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in Vietnam [Phase 2]
Phase 2 clinical trial update examining the pharmacokinetics of rifabutin when given with antiretroviral therapy in TB/HIV co-infected patie…
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CLINICAL_TRIALS trial_result · 2013-07-12Clinical Trial Update: Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion
This clinical trial evaluating a thrice-weekly directly observed treatment short-course regimen for tubercular pleural effusion has complete…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Metronidazole for Pulmonary Tuberculosis (South Korea) [Phase 2]
Phase 2 trial evaluating metronidazole for pulmonary tuberculosis, including multidrug-resistant TB. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Safety of Tuberculosis Vaccine, MVA85A, Administered by the Aerosol Route and the Intradermal Route [Phase 1]
Phase 1 study evaluating the safety of the tuberculosis vaccine MVA85A when administered by aerosol and intradermal routes.
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FDA label_change · 2013-06-27FDA Approved: RIFAMPIN — Supplemental Application (Chartwell RX, LLC)
The FDA approved a supplemental application for Rifampin filed by Chartwell RX, LLC, leading to changes in the product labeling.
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB). [Phase 2]
Phase 2 clinical trial results assessing bedaquiline (TMC207) for safety, tolerability, and anti-mycobacterial activity in participants with…
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CLINICAL_TRIALS research · 2013-06-12Clinical Trial Update: Diagnosis and Treatment of Co-infection With Human Immunodeficiency Virus /Latent Tuberculosis Infection (HIV/TBL) [Phase 4]
Phase 4 clinical trial update examining diagnosis and treatment of HIV and latent tuberculosis infection co-infection.
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CLINICAL_TRIALS trial_result · 2013-06-06Clinical Trial Update: Trial of Point-of-treatment Xpert MTB/RIF Assay [NA]
This document reports the completion of a clinical trial evaluating a point-of-treatment Xpert MTB/RIF assay for diagnosing tuberculosis. Th…
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CLINICAL_TRIALS research · 2013-06-04Clinical Trial Update: Characteristics of Mediastinal Lymph Node With False Positive FDG PET/CT Results in Lung Cancer Staging : Relation With TB and Latent TB Infection
A terminated trial update examines how false-positive mediastinal lymph node findings on FDG PET/CT for lung cancer staging may be influence…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosis [Phase 2]
Phase 2 clinical trial evaluating moxifloxacin as part of a multi-drug regimen for tuberculosis; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in Kenya [Phase 4]
A Phase 4 study in Kenya assessed the feasibility and effectiveness of delivering community-based isoniazid preventive therapy for tuberculo…
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CLINICAL_TRIALS trial_result · 2013-05-16Clinical Trial Update: To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB. [Phase 2]
Phase 2 trial evaluating the safety, tolerability, and efficacy of bedaquiline (TMC207) as part of an individualized MDR-TB treatment regime…
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: Efficacy of Antituberculous Therapy in Management of Sarcoidosis [NA]
A completed clinical trial evaluated the efficacy of antituberculous therapy in managing sarcoidosis.
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: Phase IC Study of Safety and PK of SQ109 300mg Daily [Phase 1]
A Phase I trial evaluated the safety and pharmacokinetics of SQ109 at 300 mg daily for tuberculosis. The study has completed.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Mentor Mothers: A Sustainable Family Intervention in South African Townships [Phase 2]
Phase 2 trial update on Mentor Mothers, a sustainable family intervention in South African townships, addressing HIV/AIDS with related condi…
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CLINICAL_TRIALS trial_result · 2013-04-26Clinical Trial Update: The Impact of Involving Informal Health Providers for Tuberculosis Control in Sudan [NA]
The trial completed and assessed how involving informal health providers affects tuberculosis control in Sudan.
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CLINICAL_TRIALS trial_result · 2013-04-11Clinical Trial Update: Faster Identification of TB and Evaluation of Drug Resistance in HIV-infected People
A completed clinical trial focusing on faster identification of tuberculosis and evaluation of drug resistance in people with HIV.
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CLINICAL_TRIALS research · 2013-03-29Clinical Trial Update: Epidemiology of MDR-TB in Peru
An update on the epidemiology of multidrug-resistant tuberculosis in Peru from the NCT00676754 trial led by Harvard researchers.
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CLINICAL_TRIALS trial_result · 2013-03-26Clinical Trial Update: Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB [Phase 3]
Phase 3 trial evaluating efficacy and safety of using nevirapine together with rifampicin in patients co-infected with HIV and tuberculosis;…
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective Study
A completed prospective study evaluating the value of routine bacterial culture, including tuberculosis testing, during bronchoscopy.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care Workers
A completed clinical trial comparing conversion rates of the tuberculin skin test (TST) and the QuantiFERON-TB Gold In-Tube assay in health …
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FDA approval · 2013-02-27FDA Approved: RIFADIN IV — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application to add an intravenous formulation of Rifadin (rifampin) from Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Equivalence Study of Tuberculin Purified Protein Derivative in Comparison With a Reference Standard (PPD-S2) [Phase 2]
This Phase 2 clinical trial update evaluates equivalence of tuberculin purified protein derivative (PPD-S2) against a reference standard for…