Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis (TB) in Elderly Residents of Nursing Homes?
This update reports on a completed clinical trial evaluating the effectiveness of tuberculin skin testing as a screening method for latent t…
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswana [Phase 4]
A Phase 4 clinical trial in Botswana comparing limited versus continuous isoniazid preventive therapy for tuberculosis prevention in HIV-inf…
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CLINICAL_TRIALS trial_result · 2014-01-23Clinical Trial Update: A Bioequivalence Study of Two Different Dosages of Isoniazid Tablet Formulations in Human Healthy Volunteers [Phase 1]
A Phase 1 bioequivalence study comparing two different dosages of isoniazid tablet formulations in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Access to Care and Adherence Tuberculosis (TB) Survey
This completed clinical trial evaluated access to care and adherence among people with tuberculosis.
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CLINICAL_TRIALS trial_result · 2014-01-07Clinical Trial Update: Impact of New Immunological Diagnosis Tests of Latent Tuberculosis Before Anti TNF Therapy [NA]
A completed clinical trial evaluating new immunological tests for latent tuberculosis before initiating anti-TNF therapy.
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) Patients
A completed clinical trial update monitoring monthly Interferon Gamma Releasing Assay (IGRA) testing among healthcare workers treating tuber…
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CLINICAL_TRIALS trial_result · 2013-12-24Clinical Trial Update: The Efficacy of Silymarin on the Prevention of Hepatotoxicity From Antituberculosis Drugs [NA]
A completed clinical trial evaluated whether silymarin can prevent hepatotoxicity from standard antituberculosis therapy in patients with tu…
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: Efficacy and Safety of Modified Anti-tubercular Regimens in Treatment of Tuberculosis in Patients With Underlying Compensated and Decompensated Chronic Liver Disease [NA]
A clinical trial update evaluating modified anti-tubercular regimens for tuberculosis in patients with chronic liver disease (compensated an…
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: A Study of MVA85A in Healthy Infants [Phase 2]
A Phase 2 study of the TB vaccine MVA85A in healthy infants has completed, with results posted in December 2013.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Isoniazid (INH) Treatment Based on ELISPOT Assay [NA]
Clinical trial evaluating isoniazid treatment guided by ELISPOT assay in kidney transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: The Epidemiology of TST Change in Korea
A completed Korean clinical study examined changes in tuberculin skin test results to understand the epidemiology of tuberculosis and latent…
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CLINICAL_TRIALS withdrawal · 2013-11-25Clinical Trial Update: Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating treatment for paradoxical TB-IRIS has been withdrawn.
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EMA guidance · 2013-11-22European Medicines Agency recommends two new treatment options for tuberculosis
EMA recommends two new treatment options for tuberculosis, signaling potential new therapies or regimen options under evaluation for TB mana…
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CLINICAL_TRIALS trial_result · 2013-10-31Clinical Trial Update: The Effect of Intermittent Rifampicin on Raltegravir [Phase 1]
A Phase 1 study assessed how intermittent rifampicin affects raltegravir exposure, in participants with HIV and tuberculosis. The trial has …
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa [Phase 2]
This Phase 2 trial in newborn infants in South Africa compares the TB vaccine candidate VPM1002 to BCG to evaluate safety and immunogenicity…
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Tuberculosis (TB) Immunotherapy Phase 2 Study [Phase 2]
Phase 2 tuberculosis immunotherapy trial sponsored by Lisichansk Regional Tuberculosis Dispensary has completed.
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CLINICAL_TRIALS research · 2013-10-01Clinical Trial Update: Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) Infection [NA]
This clinical trial update covers two-stage tuberculin skin testing (PPD) in individuals with HIV infection. The study status is completed.
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CLINICAL_TRIALS trial_result · 2013-10-01Clinical Trial Update: A Registry of Tuberculosis Cases in the CPCRA
This entry reports a completed registry study documenting tuberculosis cases within the CPCRA network, sponsored by NIAID, involving HIV inf…
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CLINICAL_TRIALS trial_result · 2013-08-30Clinical Trial Update: A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampin [Phase 2]
A Phase 2 pilot study evaluating the pharmacokinetics of colchicine in patients taking rifampin has completed.
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CLINICAL_TRIALS trial_result · 2013-08-29Clinical Trial Update: Deworming Against Tuberculosis [NA]
A completed clinical trial sponsored by Linköping University studied deworming therapy in tuberculosis.
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FDA approval · 2013-08-28FDA Approved: SIRTURO — Supplemental Application (Janssen Products, LP)
The FDA approved a supplemental application for SIRTURO (bedaquiline fumarate) submitted by Janssen Products, LP.
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers [Phase 1]
Phase 1 study evaluating the safety, tolerability, pharmacokinetics, and whole blood activity measurements of PNU-100480 after multiple oral…
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CLINICAL_TRIALS trial_result · 2013-08-27Clinical Trial Update: Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults [Phase 1]
Phase 1 safety, tolerability, and pharmacokinetics study of single doses of PNU-100480 in healthy adults has completed, providing initial sa…
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FDA approval · 2013-08-21FDA Approved: RIFAMPIN — Original Application (Lupin Pharmaceuticals, Inc.)
The FDA approved Lupin Pharmaceuticals' original application for rifampin, making a generic rifampin product available through an approved A…
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteers [Phase 1]
This Phase 1 study evaluates escalating single-dose safety, tolerability, and pharmacokinetics of SQ109 in healthy volunteers. The goal is t…