Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-27Clinical Trial Results: Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis [Phase 3]
Phase 3 pharmacokinetic/pharmacodynamic study evaluating high-dose rifapentine and moxifloxacin for tuberculosis treatment completed with po…
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CLINICAL_TRIALS trial_result · 2026-08-26Clinical Trial Results: Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum
A terminated clinical trial analyzing pharmacokinetic properties of antiretroviral and anti-tuberculosis drugs during pregnancy and postpart…
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Results: Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) [Phase 2]
Phase 2 trial assessing safety and tolerability of metformin in people with tuberculosis and HIV coinfection has completed with results post…
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CLINICAL_TRIALS trial_result · 2026-07-30Clinical Trial Results: ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa [NA]
A completed clinical trial conducted in South Africa evaluating new pathways to prevention through community TB screening, with results post…
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Results: TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB Infection [NA]
Study results on rifapentine pharmacokinetics in children undergoing treatment for latent tuberculosis infection.
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CLINICAL_TRIALS trial_result · 2026-07-06Clinical Trial Results: TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB [Phase 1, Phase 2]
Clinical trial results report on safety and tolerability of low-dose linezolid in multi-drug resistant and extensively drug-resistant tuberc…
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment [NA]
Completed clinical trial evaluating traditional DOT and electronic DOT for tuberculosis treatment; results posted.
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CLINICAL_TRIALS trial_result · 2026-06-25Clinical Trial Results: Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in Children With MDR-TB With and Without HIV [Phase 1, Phase 2]
Phase 1/2 trial evaluating delamanid with an optimized background regimen for pediatric multidrug-resistant tuberculosis, including subgroup…
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis [Phase 2]
Phase 2 trial results evaluating the early bactericidal activity, safety, and tolerability of oral GSK3036656 in combination regimens for ri…
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CLINICAL_TRIALS trial_result · 2026-06-12Clinical Trial Results: Targeted Universal TB Testing With Simultaneous TPT Prescribing Among People Living With HIV in South Africa [NA]
Trial results on targeted universal TB testing with simultaneous tuberculosis preventive therapy prescribing among people living with HIV in…
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EMA approval · 2026-06-09EMA Authorised: Dovprela (previously Pretomanid FGK) (pretomanid) — Mylan IRE Healthcare Limited
EMA authorised Dovprela (pretomanid) for multidrug-resistant tuberculosis; orphan medicine.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Results: Safety, Tolerability, Pharmacokinetics (PK), and Food Effect of MK-7762 in Healthy Adults [Phase 1]
Phase 1 trial assessing safety, tolerability, PK, and food effect of MK-7762 in healthy adults.
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EMA approval · 2026-06-03EMA Authorised: Sirturo (bedaquiline fumarate) — Janssen-Cilag International N.V.
EMA authorises Sirturo (bedaquiline fumarate) for multidrug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: BCG for Therapeutic Use Phase Ⅲ Clinical Trial [Phase 3]
Phase 3 clinical trial update for therapeutic use of BCG; the study is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults [Phase 3]
A Phase 3 trial update for the M72/AS01E vaccine in adolescents and adults evaluating efficacy and safety for tuberculosis.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of the M72/AS01E TB vaccine in adolescents and adults is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: BCG Revaccination Study in Diabetic and Non-Diabetic Adults [NA]
This entry notes an ongoing clinical trial evaluating revaccination with the Bacillus Calmette-Guérin (BCG) vaccine in adults, comparing dia…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Quantitative Measurement of Plasma and Urine MTB Cell-free DNA Level
A clinical trial is evaluating quantitative measurement of Mycobacterium tuberculosis cell-free DNA in plasma and urine, currently recruitin…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Hospital and Extra-hospital Nursing Care for Tuberculosis [NA]
This clinical trial update describes a study on hospital and extra-hospital nursing care for tuberculosis, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis [Phase 2]
A Phase 2 study is assessing bactericidal activity and safety of adding nicotinamide to bedaquiline, pretomanid, and linezolid for drug-susc…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma
This clinical trial update from NIAID studies mycobacterial and opportunistic infections in HIV-negative Thai and Taiwanese patients with au…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Prevention and Mass Screening of TB in Prisons in Paraguay [NA]
Clinical trial update from Universidad Nacional de Caaguazu describes a study on prevention and mass screening for tuberculosis and tubercul…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Training Protocol on the Natural History of Tuberculosis
Sponsored by NIAID, this ClinicalTrials.gov entry outlines a training protocol to study the natural history of tuberculosis, including laten…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Blood Tuberculosis DNA Levels to Monitor Tuberculosis Treatment
A clinical trial update evaluating blood TB DNA as a biomarker to monitor tuberculosis treatment.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients
The University of Oxford is conducting a study to assess the immunogenicity of COVID-19 vaccines in patients with tuberculosis; the study is…