Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccination [Phase 1]
Phase 1 study evaluating pre-clearance of latent tuberculosis infection and revaccination with the BCG vaccine.
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents [Phase 2]
Phase 2 trial assessing safety and immunogenicity of a TB vaccine candidate in healthy HIV-negative adolescents; results posted after comple…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults. [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of a TB vaccine candidate in HIV-positive adults; results available.
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Heterologous Effects of BCG in Healthy UK Adults [NA]
Completed clinical trial from the University of Oxford assessing non-specific (heterologous) immune effects of the BCG vaccine in healthy UK…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Pharmacokinetics and Safety of Moxifloxacin [Phase 4]
A Phase 4 trial evaluating the pharmacokinetics and safety of moxifloxacin for tuberculosis was terminated.
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EMA guidance · 2016-11-18Workshop: towards new treatments for tuberculosis
EMA hosted a workshop focused on exploring new treatment options for tuberculosis to discuss research, challenges, and potential regulatory …
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Intensifying Multi-Drug Resistant Tuberculosis Contact Tracing by Social Network Analysis
A completed clinical trial from Oxford University Clinical Research Unit in Vietnam examining intensified contact tracing for multidrug-resi…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) [NA]
A completed study (NIDIAG-Fever) evaluated rapid diagnostic tests and clinical/laboratory predictors to diagnose tropical diseases in patien…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Could the Stroke Volume Variation Predict a Fluid Responsiveness in Thoracotomy?
The trial investigated whether stroke volume variation can predict fluid responsiveness during thoracotomy. It was sponsored by Samsung Medi…
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: Evaluation of a LAM FLISA for the Diagnosis of Tuberculosis
This document reports a completed clinical trial evaluating a LAM FLISA assay for diagnosing tuberculosis.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Study of Daily Rifapentine for Pulmonary Tuberculosis [Phase 2]
Phase 2 trial evaluating daily rifapentine for pulmonary tuberculosis has completed; results posted in 2016.
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CLINICAL_TRIALS research · 2016-09-23Clinical Trial Update: Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis
This clinical trial update examines the etiologies, investigations, and outcomes of patients presenting with hemoptysis.
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: The Protective Effect for Liver Organ in Patients With Anti-TB Drugs Using of Acetylcysteine (NAC) [Phase 4]
A Phase 4 clinical trial evaluating whether N-acetylcysteine protects the liver in patients receiving anti-tuberculosis drugs to prevent dru…
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Immunobiology of Diabetes and Tuberculosis [NA]
This is an update on a Stanford University trial investigating the immunobiology of diabetes and tuberculosis; the study was terminated and …
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CLINICAL_TRIALS trial_result · 2016-08-02Clinical Trial Update: Phase I Trial of DAR-901 [Phase 1]
The Phase I trial of DAR-901 for tuberculosis has completed.
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EMA guidance · 2016-08-01Development of medicines to treat tuberculosis
EMA discusses approaches and considerations for developing medicines to treat tuberculosis, outlining priorities, regulatory expectations, a…
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Probe Melting Technology for Rapid Detection of Drug Resistant Tuberculosis
This document reports an update on a clinical trial evaluating probe melting technology for rapid detection of drug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: TB Contact Investigation: Behavioral Intervention
This completed clinical trial evaluated a behavioral intervention to improve tuberculosis contact investigation.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Indigenous Outreach Among Injection Drug Users to Treat and Control TB
This clinical trial update reports the completion of a study evaluating Indigenous outreach among injection drug users to treat and control …
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults [Phase 1]
A Phase 1 safety trial evaluating ChAdOx1 85A vaccination with and without an MVA85A boost in healthy adults has been completed. The trial w…
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CLINICAL_TRIALS research · 2016-05-12Clinical Trial Update: DNA Sequencing of MDR TB in Eastern Siberia
This document provides an update on a clinical trial that involves DNA sequencing of multi-drug resistant tuberculosis samples collected in …
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB [Phase 2]
This clinical trial update summarizes safety findings from a Phase 2 study of AERAS-402 in adults recently treated for pulmonary tuberculosi…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: The Role of Tuberculosis in Chronic Obstructive Lung Disease
This clinical trial update reports on a study assessing how tuberculosis relates to chronic obstructive pulmonary disease.
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: A Study to Evaluate Safety and Immunogenicity of AERAS-402 Administered in HIV-negative, BCG-vaccinated, QFT (+) and (-) Adults Without Evidence of TB [Phase 1]
Phase 1 study evaluating the safety and immunogenicity of the TB vaccine AERAS-402 in HIV-negative, BCG-vaccinated adults without evidence o…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 (C-011-404) [Phase 1]
Phase I study evaluating the safety and immunogenicity of the TB vaccine candidate AERAS 404 (C-011-404) has completed.