Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-01-25Clinical Trial Update: Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating interferon-gamma as part of complex treatment for patients with HIV and tuberculosis has completed, wi…
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: BTZ-043 Dose Evaluation in Combination and Selection [Phase 2]
Phase 2 clinical trial evaluating BTZ-043 dose in combination therapy for pulmonary tuberculosis and other specified pulmonary tuberculosis.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: BCG Revaccination in Children and Adolescents [Phase 3]
Phase 3 clinical trial update on BCG revaccination in children and adolescents has been suspended.
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) [Phase 2, Phase 3]
A clinical trial investigated atorvastatin as a treatment adjunct for pulmonary tuberculosis in Nigeria, spanning Phase 2 and Phase 3 and no…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) [NA]
An implementation trial compared different delivery methods for the 3HP regimen (isoniazid–rifapentine) to prevent tuberculosis in individua…
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis [Phase 2]
Phase 2 trial updating early bactericidal activity, safety, and tolerability of GSK3036656 in drug-sensitive pulmonary tuberculosis complete…
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) [Phase 4]
Phase 4 clinical trial assessing preventive therapy for TB in alcohol drinkers; study completed with posted results.
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FDA approval · 2023-10-12FDA Approved: SIRTURO — Supplemental Application (Janssen Products, LP)
The FDA approved a supplemental application for SIRTURO (bedaquiline fumarate) submitted by Janssen Products, LP.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin [Phase 2]
Phase 2 clinical trial evaluating safety, pharmacokinetics, and hematologic effects of imatinib with and without isoniazid and rifabutin in …
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis [Phase 2]
A Phase 2 trial comparing standard-dose versus double-dose dolutegravir in people with HIV-associated tuberculosis has completed, with resul…
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis [Phase 2]
A Phase 2b dose-finding study evaluating pravastatin as adjunctive therapy for tuberculosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-25Clinical Trial Update: A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis [Phase 3]
Phase 3 pragmatic trial evaluating optimized dosing of rifampicin and moxifloxacin for drug-susceptible pulmonary tuberculosis, with HIV co-…
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CLINICAL_TRIALS trial_result · 2023-08-25Clinical Trial Update: Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy Volunteers [NA]
A completed clinical trial evaluating the specificity of a recombinant tuberculosis allergen in BCG-vaccinated healthy volunteers; results p…
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FDA approval · 2023-08-16FDA Approved: RIFADIN IV — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application to add an intravenous formulation of rifampin (RIFADIN IV).
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FDA approval · 2023-08-16FDA Approved: RIFAMPIN — Supplemental Application (EPIC PHARMA, LLC)
FDA approved a supplemental application for Rifampin from Epic Pharma, LLC. The approval likely updates labeling or indications for the prod…
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes [NA]
A completed clinical trial evaluated how alcohol consumption affects outcomes of tuberculosis treatment, with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB [Phase 2]
Phase 2 trial assessing early bactericidal activity of a rifampin-meropenem-amoxicillin/clavulanate combination in adults with pulmonary tub…
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: New Reusable Mask Design With Superior Filtration and Fit [NA]
A completed clinical trial update reports a new reusable mask design with improved filtration and fit, with results posted in 2023.
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FDA approval · 2023-06-30FDA Approved: RIFAMPIN — Supplemental Application (Lupin Pharmaceuticals, Inc.)
The FDA approved a Lupin Pharmaceuticals supplemental application for Rifampin (ANDA 090034), resulting in an approved update to the generic…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis [Phase 3]
Phase 3 trial evaluating various doses and durations of a regimen including linezolid with bedaquiline and pretomanid for drug-resistant tub…
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: Statin Adjunctive Therapy for TB [Phase 2]
Phase 2 trial investigating statin adjunctive therapy for tuberculosis; study completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-26Clinical Trial Update: The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis [Phase 2]
Phase 2 trial update for a combination of cephalexin and amoxicillin-clavulanate in pulmonary tuberculosis (BLAST-1).
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: Rifampin and the Contraceptive Implant [Phase 4]
Phase 4 trial updating on the interaction between rifampin and the contraceptive implant; results posted after completion.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus [Phase 3]
A Phase 3 clinical trial investigating preventive treatment for latent tuberculosis infection in people with diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2023-03-23Clinical Trial Update: Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy [Phase 2]
Phase 2 trial assessing safety and efficacy of high-dose rifampicin in TB-HIV co-infected patients on efavirenz- or dolutegravir-based ART c…