Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Introduction of Dispersible 3HP Formulations for TB Preventive Treatment in Children: a Multi-country Evaluation
A multi-country evaluation is introducing dispersible 3HP formulations for TB preventive treatment in children; the trial is currently NOT_Y…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Xpert Active Case-finding Trial 3 (XACT-3) [NA]
Xpert Active Case-finding Trial 3 (XACT-3) is an ongoing tuberculosis trial conducted by the University of Cape Town. The study status is AC…
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load [Phase 2, Phase 3]
A completed Phase 2/3 dose-escalation trial evaluated the pharmacokinetics of atazanavir when co-administered with rifampicin in HIV-positiv…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case Detection [NA]
A Bahir Dar University-led trial evaluating the integration of traditional tuberculosis care with modern health services has completed. The …
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Gene-guided N-acetyl Cysteine for Prophylaxis of Anti-tuberculous Drug- Induced Hepatitis [Phase 4]
Phase 4 clinical trial evaluating gene-guided N-acetylcysteine to prevent anti-tuberculosis drug-induced hepatitis, currently recruiting.
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy [Phase 1]
A Phase 1 clinical trial is evaluating the safety and tolerability of adding chloroquine to standard anti-tuberculosis therapy.
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FDA approval · 2024-06-21FDA Approved: SIRTURO — Supplemental Application (Janssen Products, LP)
FDA approved Janssen's supplemental application for SIRTURO (bedaquiline fumarate), updating the labeling to reflect the approved changes.
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: New Strategies for Assessment of the Persistence of Viable Bacilli in Latent and Active Tuberculosis
A clinical trial update describing new strategies for assessing the persistence of viable Bacilli in latent and active tuberculosis to impro…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: The Impact of Malnutrition on Immune Responses to Tuberculosis
A clinical trial in India is investigating how malnutrition in children affects immune responses to tuberculosis; the study is currently act…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Preventive Therapy for Tuberculosis in HIV Infected Persons [Phase 3]
This Clinical Trial Update reports the completion of a Phase 3 trial evaluating preventive therapy for tuberculosis in HIV-infected individu…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients
Completed clinical trial evaluating antibiotic-induced liver injury as a stratification tool for patients with tuberculosis.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Tuberculosis Research of INA-RESPOND On Drug Resistance
The clinical trial update reports completion of the INA-RESPOND tuberculosis drug-resistance study, with results posted in May 2024. The stu…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Evaluation of Four Stool Processing Methods Combined With Xpert MTB/RIF Ultra for Diagnosis of Intrathoracic Paediatric TB (TB-Speed - Stool Processing) [NA]
This update reports the completion of a diagnostic study evaluating four stool processing methods in combination with the Xpert MTB/RIF Ultr…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania
This ClinicalTrials.gov entry indicates a study on silicosis and silicotuberculosis among small-scale gemstone miners in Northern Tanzania i…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Airborne Preventive Measures to Reduce New TB Infections in Household Contacts [NA]
The clinical trial NCT04938596 on airborne preventive measures to reduce new tuberculosis infections in household contacts has completed.
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Study of GeneXpert Mycobacterium Tuberculosis/ Rifampicin (MTB/RIF) Versus the Routine Methods for Detection of Mycobacterium Tuberculosis
This clinical trial update outlines a study comparing the GeneXpert MTB/RIF diagnostic test with routine methods for detecting Mycobacterium…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: COMPArison of Screening Strategies for Active TuBerculosis (COMPASS-TB)
The COMPASS-TB trial comparing screening strategies for active tuberculosis and latent tuberculosis infection has completed.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and Adults
A completed University of Virginia clinical trial evaluates urine colorimetry as a method to study tuberculosis pharmacokinetics in children…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: TB and Sarcoidosis Granuloma
Karolinska Institutet completed a clinical trial related to granulomas in tuberculosis and sarcoidosis. The update notes the study status as…
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis [Phase 2]
Phase 2 clinical trial investigating adjunctive acetylsalicylic acid and ibuprofen for pulmonary and MDR tuberculosis; current status is unk…
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial) [Phase 3]
Phase 3 clinical trial assessing adjunctive corticosteroids for tuberculous meningitis in HIV-infected adults has completed.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old. [Phase 2]
Phase 2 clinical trial exploring skin test dosage of EEC for tuberculosis and assessing safety and preliminary efficacy across a wide age ra…
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: Azithromycin as Host-directed Therapy for Pulmonary Tuberculosis [Phase 2]
Phase 2 clinical trial exploring azithromycin as host-directed therapy for pulmonary tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Interrupting HIV and TB Stigma in the Household in Uganda [NA]
A completed clinical trial in Uganda explored interventions to interrupt HIV and tuberculosis stigma within households, with results posted …
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB [Phase 4]
Phase 4 trial update evaluating the pharmacokinetics of twice-daily or once-daily DTG (50 mg) in children with HIV and tuberculosis.