Tuberculosis
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EMA withdrawal · 2026-01-05EMA Withdrawn: Granupas (previously Para-aminosalicylic acid Lucane) (para-aminosalicylic acid) — Eurocept International B. V.
The EMA has withdrawn Granupas, a para-aminosalicylic acid product, from the European market for tuberculosis treatment. The decision date i…
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CLINICAL_TRIALS withdrawal · 2025-12-17Clinical Trial Update: Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans [Phase 1]
A Phase 1 safety/challenge study of the BCG TICE Bacillus Calmette-Guérin vaccine for testing tuberculosis immunity in healthy adults has be…
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CLINICAL_TRIALS withdrawal · 2025-08-17Clinical Trial Update: Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa [Phase 1, Phase 2]
The Phase 1/2 trial evaluating safety and immunogenicity of VPM1002 vaccination or BCG revaccination for tuberculosis in HIV-infected and un…
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CLINICAL_TRIALS withdrawal · 2025-05-11Clinical Trial Update: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants [Phase 1]
The Phase 1 study of GSK2556286 in healthy adults has been terminated. The update notes safety, tolerability and pharmacokinetics aspects of…
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CLINICAL_TRIALS withdrawal · 2025-02-06Clinical Trial Update: Can Screening People Registering With Primary Care Improve the Detection of Tuberculosis?
A clinical trial evaluating screening of people registering with primary care to improve tuberculosis detection has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2021-09-20Clinical Trial Update: A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects [Phase 4]
A Phase 4 pharmacokinetic/pharmacodynamic study evaluating interactions between bictegravir, tenofovir alafenamide, and rifapentine in healt…
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CLINICAL_TRIALS withdrawal · 2018-04-10Clinical Trial Update: A Phase II Study of H56:IC31 in Healthy Adolescents [Phase 2]
A Phase II study of the TB vaccine H56:IC31 in healthy adolescents has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-09-11Clinical Trial Update: Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin [Phase 3]
Phase 3 trial evaluating a four-drug regimen (delamanid, linezolid, pyrazinamide, levofloxacin) for multidrug-resistant tuberculosis has bee…
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CLINICAL_TRIALS withdrawal · 2017-05-24Clinical Trial Update: Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis
A clinical trial investigating the biologic basis for increased susceptibility of smokers to pulmonary tuberculosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-04Clinical Trial Update: A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infection [Phase 3]
A Phase 3 randomized trial of prednisone as adjunctive therapy for hospitalized patients with pulmonary tuberculosis and HIV co-infection wa…
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CLINICAL_TRIALS withdrawal · 2015-12-09Clinical Trial Update: Tuberculosis Research Blood Bank
A tuberculosis-related clinical trial sponsored by NYU Langone Health has been withdrawn from the clinical trials registry, with no enrollme…
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CLINICAL_TRIALS withdrawal · 2014-03-24Clinical Trial Update: Effects of SQ109 on QTc Interval in Healthy Subjects [Phase 1]
Phase 1 trial evaluating the effects of SQ109 on the QTc interval in healthy subjects has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2013-11-25Clinical Trial Update: Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating treatment for paradoxical TB-IRIS has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-01-20Clinical Trial Update: Vitamin D in Active Tuberculosis (TB) Study [NA]
A clinical trial investigating vitamin D supplementation in active tuberculosis has been withdrawn.