Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Triage UltraSound in Tb Endemic Regions
Clinical trial on triage ultrasound in tuberculosis-endemic regions has completed. The document notes the study status as COMPLETED.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) [Phase 3]
Phase 3 endTB-Q trial evaluating regimens with newly approved drugs for multidrug-resistant tuberculosis with fluoroquinolone resistance has…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants [Phase 3]
A Phase 3 trial comparing VPM1002 to the BCG vaccine for prevention of tuberculosis infection in infants has completed.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Evaluating Newly Approved Drugs for Multidrug-resistant TB [Phase 3]
Phase 3 clinical trials evaluating newly approved drugs for multidrug-resistant tuberculosis have completed, according to a trial update.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Kharituwe TB Contact Tracing Study [NA]
The Kharituwe TB Contact Tracing Study has completed and posted results, focusing on tuberculosis and HIV and conducted by Johns Hopkins Blo…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers [Phase 1]
Phase 1 study results of an aerosol BCG challenge in volunteers previously vaccinated with BCG to evaluate safety and immune responses.
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Predicting the Future: Incipient Tuberculosis
This clinical trial update reports the completion of a study on predicting incipient tuberculosis.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB) [Phase 2]
An exploratory Phase 2 study of bedaquiline (TMC207) in Japanese patients with pulmonary multidrug-resistant tuberculosis has completed. The…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) [Phase 2]
Phase 2 clinical trial evaluating the early bactericidal activity of tedizolid and linezolid against tuberculosis, including multidrug-resis…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Butterfly Pea Flower (Clitoria Ternatea) for Adjuvant TB Treatment [EARLY_Phase 1]
A completed early Phase 1 trial evaluated butterfly pea flower extract (Clitoria ternatea) as an adjuvant therapy for tuberculosis.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: TB PCR in BAL and EBUS-TBNA
A clinical trial evaluating PCR testing for tuberculosis in bronchoalveolar lavage (BAL) and EBUS-TBNA has completed.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Drinkers' Intervention to Prevent Tuberculosis (DIPT Study) [NA]
This completed clinical trial (DIPT Study) tested a drinkers' intervention intended to prevent tuberculosis in people with HIV infection. Re…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults [Phase 1]
A Phase 1 trial evaluating safety, tolerability, and pharmacokinetics of the TB drug candidate TBI-223 in healthy adults has completed with …
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment [Phase 1]
Phase 1 study evaluating absorption, elimination and safety of 14C-labeled BTZ-043, a novel tuberculosis drug. The trial has completed and r…
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Evaluating the Potential of Large Language Models for Respiratory Disease Consultations [NA]
This completed clinical trial evaluated the potential of large language models to assist respiratory disease consultations. It covered multi…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet
This clinical trial update reports on the adequacy of a new pediatric HRZ tablet (isoniazid/rifampin/pyrazinamide) for treating tuberculosis…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda [NA]
A completed Makerere University study in Uganda evaluated SMS reminders, phone calls, and financial incentives to improve linkage to care am…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Whole Genome Sequencing of Tuberculosis for Disease Control in Madagascar [NA]
This completed trial investigates whole genome sequencing of Mycobacterium tuberculosis to inform tuberculosis control efforts in Madagascar…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Potential Role of Microbiome in Tuberculosis
A clinical trial investigating the potential role of the microbiome in tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults [Phase 1]
Phase 1 study assessing drug-drug interaction of TB antibiotic candidate TBAJ-876 in healthy adults has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Integrated Discovery and Development of Innovative TB Diagnostics
A Harvard-led clinical trial evaluating innovative diagnostics for pulmonary tuberculosis has completed, marking a registry status update.
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Six-months Versus Nine-months ATT for Ocular TB [Phase 4]
Completed Phase 4 trial comparing six-month versus nine-month anti-tuberculosis therapy durations for ocular tuberculosis, evaluating condit…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Endurance Training in Patients With Post-TB Lung Disease [NA]
A completed clinical trial evaluated endurance training in patients with post-TB lung disease. The study, sponsored by Riphah International …
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected Patients [Phase 4]
Phase 4 clinical trial evaluating raltegravir with lamivudine/abacavir in HIV infection co-infected with tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care [Phase 3]
Phase 3 trial evaluating a short-course regimen containing bedaquiline, delamanid, and linezolid versus the current standard of care for rif…