Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-07-01Clinical Trial Update: A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG Vaccination [Phase 1]
Phase 1 study by the University of Oxford to quantify the immune response after Bacille Calmette-Guérin vaccination and characterize the imm…
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CLINICAL_TRIALS trial_result · 2010-06-14Clinical Trial Update: QuantiFERON Change During Anti-tuberculosis Medication
Clinical trial update describing how QuantiFERON interferon-gamma release assay results change during anti-tuberculosis medication, based on…
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CLINICAL_TRIALS trial_result · 2010-05-26Clinical Trial Update: Treatment of Latent Tuberculosis Infection With Isoniazid [Phase 4]
Phase 4 clinical trial evaluating isoniazid for latent tuberculosis infection; the study has completed.
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CLINICAL_TRIALS trial_result · 2010-05-20Clinical Trial Update: Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison With BCG in Healthy Male Volunteers [Phase 1]
Phase 1 dose-escalation study assessing safety and immunogenicity of VPM1002 compared with BCG in healthy male volunteers; study completed.
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CLINICAL_TRIALS trial_result · 2010-04-08Clinical Trial Update: The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure
This completed trial assesses the timing of positive conversion of an interferon-γ releasing assay after tuberculosis exposure to evaluate t…
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CLINICAL_TRIALS trial_result · 2010-03-29Clinical Trial Update: Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings [NA]
This document provides an update on a completed clinical trial evaluating the effectiveness of directly observed therapy for combined HIV an…
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CLINICAL_TRIALS trial_result · 2010-02-19Clinical Trial Update: Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal Adenopathy [NA]
A completed clinical trial evaluating rapid on-site cytopathologic evaluation for diagnosing hilar/mediastinal lymphadenopathy, including ca…
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: A Phase I Study to Assess the Safety and Immunogenicity of Tuberculosis (TB) Vaccine Candidates FP85A and MVA85A [Phase 1]
Phase I study update reporting safety and immunogenicity results for TB vaccine candidates FP85A and MVA85A; study completed.
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: Safety, Immunogenicity, and Impact of MVA85A, on the Immunogenicity of the EPI Vaccines [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of the MVA85A tuberculosis vaccine and its impact on the immunogenicity of Expanded P…
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: A Study of MVA85A in Healthy Children and Infants [Phase 2]
A Phase 2 trial evaluating the MVA85A tuberculosis vaccine in healthy children and infants has been completed.
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CLINICAL_TRIALS trial_result · 2010-01-27Clinical Trial Update: Tuberculosis Treatment Shortening Trial [Phase 3]
Phase 3 trial update on shortening tuberculosis treatment, completed with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-01-18Clinical Trial Update: T-Cell Turnover Following Vaccination With MVA85A [Phase 1]
A Phase 1 trial in tuberculosis examined T-cell turnover after vaccination with MVA85A. The study is reported as completed.
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CLINICAL_TRIALS trial_result · 2010-01-13Clinical Trial Update: A Trial of Isoniazid for the Reversion of Interferon Gamma ELISPOT in Tuberculosis (TB) Case Contacts [NA]
A completed clinical trial evaluating whether isoniazid can reverse IFN-gamma ELISPOT responses in tuberculosis case contacts.
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CLINICAL_TRIALS trial_result · 2010-01-08Clinical Trial Update: Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST) [Phase 4]
ClinicalTrials.gov update for the THIRST trial (Tuberculosis and HIV Immune Reconstitution Syndrome) Phase 4. The study has completed enroll…
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CLINICAL_TRIALS trial_result · 2009-11-10Clinical Trial Update: Anti-tuberculosis (TB) Drug Levels and Hepatotoxicity
Completed clinical trial update examining anti-tuberculosis drug levels and associated hepatotoxicity; data relate to hepatitis and tubercul…
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CLINICAL_TRIALS trial_result · 2009-10-08Clinical Trial Update: Safety and Efficacy of Two Once Daily Anti Retroviral Treatment Regimens Along With Anti-tuberculosis Treatment [Phase 3]
Phase 3 trial update assessing two once-daily antiretroviral regimens used alongside anti-tuberculosis therapy for TB/HIV coinfection; curre…
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CLINICAL_TRIALS trial_result · 2009-09-23Clinical Trial Update: The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation
The trial evaluated the role of high-resolution CT imaging in investigating tuberculosis outbreaks. The study has completed.
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CLINICAL_TRIALS trial_result · 2009-09-17Clinical Trial Update: Study of Health Personnel and the Assistance to Patients With Tuberculosis in Hospital Environment
A completed clinical trial studying health personnel involvement in caring for tuberculosis patients in a hospital setting.
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CLINICAL_TRIALS trial_result · 2009-08-20Clinical Trial Update: Diagnosis of Latent Tuberculosis(TB) Infection in Health Care Workers Using TST and Whole Blood Interferon-γ Assay
A completed clinical trial comparing the diagnostic performance of tuberculin skin testing (TST) and a whole-blood Interferon-γ assay for la…
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CLINICAL_TRIALS trial_result · 2009-08-04Clinical Trial Update: Nutrition, Diabetes and Pulmonary TB/HIV [Phase 3]
A Phase 3 clinical trial investigating nutrition, diabetes, and pulmonary tuberculosis/HIV has completed.
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CLINICAL_TRIALS trial_result · 2009-07-16Clinical Trial Update: The Effectiveness of Health Facility-based and Community-based Care for Tuberculosis [Phase 4]
Phase 4 trial evaluating the effectiveness of health facility-based versus community-based care for tuberculosis, completed.
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CLINICAL_TRIALS trial_result · 2009-07-09Clinical Trial Update: Rapid Characterization of Paucibacillary TB Along Tex/Mex Border
This completed trial from The University of Texas Health Science Center, Houston, reports rapid characterization of paucibacillary tuberculo…
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CLINICAL_TRIALS trial_result · 2009-06-25Clinical Trial Update: Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis [Phase 1, Phase 2]
Early bactericidal activity data for multiple drugs (linezolid, gatifloxacin, levofloxacin, isoniazid, moxifloxacin) in HIV-negative adults …
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CLINICAL_TRIALS trial_result · 2009-04-22Clinical Trial Update: Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity [NA]
A completed clinical trial evaluated the effect of N-acetylcysteine in preventing or mitigating liver toxicity caused by anti-tuberculosis d…
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CLINICAL_TRIALS trial_result · 2009-04-14Clinical Trial Update: Effectiveness of the TB Contact Priority Model
NHLBI-sponsored trial completed to evaluate the effectiveness of a tuberculosis contact priority model.