Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Safety and Efficacy of Oral Immunomodulator in Tuberculosis (TB) and TB/HIV Patients [Phase 2]
Phase 2 clinical trial assessing the safety and efficacy of an oral immunomodulator in tuberculosis and TB/HIV patients has completed.
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Role of Vitamin D in Innate Immunity to Tuberculosis [NA]
A completed clinical trial evaluating whether vitamin D supplementation modulates innate immunity in tuberculosis.
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®) [Phase 1]
A Phase 1 bioequivalence study compared a fixed-dose combination of rifampicin and isoniazid (Myrin 2) with rifampicin alone (Rimactane) to …
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons [NA]
Clinical trial update notes the completion of a study evaluating isoniazid plus antiretroviral therapy to prevent tuberculosis in HIV-infect…
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CLINICAL_TRIALS trial_result · 2012-06-11Clinical Trial Update: A Phase 1, Open Label, Placebo-Controlled Study to Evaluate the Effect of GSK1349572 on Iohexol and Para-Aminohippurate Clearance in Healthy Subjects [Phase 1]
Phase 1 trial update describing a Phase 1 open-label, placebo-controlled pharmacokinetic study of GSK1349572 (dolutegravir) assessing its ef…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenz [Phase 2]
This Phase 2 pharmacokinetic study reports on the intermittent rifabutin and isoniazid regimens co-administered with daily efavirenz in indi…
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CLINICAL_TRIALS trial_result · 2012-03-19Clinical Trial Update: Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries? [Phase 4]
Phase 4 trial evaluating whether administering the Bacillus Calmette-Guérin (BCG) vaccine at birth to low birth weight infants in developing…
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CLINICAL_TRIALS trial_result · 2012-03-19Clinical Trial Update: Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected Patients [NA]
This update reports on the medical and economic implications of using Interferon-Gamma Release Assays (IGRAs) to diagnose latent tuberculosi…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: Early vs Late Introduction of Antiretroviral Therapy in HIV-infected Patients With Tuberculosis (ANRS 1295 CAMELIA) [Phase 3]
Phase 3 trial CAMELIA compared early versus delayed initiation of antiretroviral therapy in HIV-infected patients with tuberculosis; the stu…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults [Phase 1]
A Phase 1 bioequivalence study comparing a fixed-dose combination of rifampicin, isoniazid, ethambutol and pyrazinamide per tablet to the eq…
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CLINICAL_TRIALS trial_result · 2012-02-16Clinical Trial Update: Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage [Phase 4]
This Phase 4 study evaluates safety and efficacy of different regimens for reintroducing anti-tuberculosis drugs in patients who developed l…
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CLINICAL_TRIALS trial_result · 2012-02-15Clinical Trial Update: Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO) [Phase 2, Phase 3]
A Phase 2/3 study (ANRS 12146 CARINEMO) comparing nevirapine to efavirenz in HIV-TB co-infected patients has completed Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural Lesotho [NA]
This update reports a completed trial comparing door-to-door versus community gathering approaches for HIV counseling and testing in rural L…
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised Patients
A completed clinical trial evaluated the diagnostic usefulness of the Interferon Gamma Release Assay for detecting active tuberculosis in im…
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CLINICAL_TRIALS trial_result · 2012-01-10Clinical Trial Update: Quantiferon for Detection of Latent Tuberculosis in Healthcare Workers [Phase 4]
Phase 4 clinical trial evaluating the Quantiferon test for detecting latent tuberculosis in healthcare workers has completed.
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CLINICAL_TRIALS trial_result · 2011-11-22Clinical Trial Update: Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampin [Phase 3]
Phase 3 trial comparing efavirenz-based versus nevirapine-based antiretroviral therapy in HIV-infected patients receiving rifampin. The stud…
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CLINICAL_TRIALS trial_result · 2011-11-21Clinical Trial Update: Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison to BCG in Healthy Volunteers in South Africa [Phase 1]
Phase 1 dose-escalation study assessing safety and immunogenicity of VPM1002 compared with BCG in healthy volunteers in South Africa has com…
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: Appropriate Timing of HAART in Co-infected HIV/TB Patients [Phase 4]
This update covers a Phase 4 trial evaluating the optimal timing of HAART in patients co-infected with HIV and tuberculosis, which was termi…
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CLINICAL_TRIALS trial_result · 2011-11-16Clinical Trial Update: Treatment Adherence of Tuberculosis Medicines [NA]
Completed clinical trial update focusing on adherence to tuberculosis medicines. The document notes the trial status as completed for the tu…
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CLINICAL_TRIALS trial_result · 2011-11-08Clinical Trial Update: Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis [Phase 3]
A Phase 3 trial conducted by All India Institute of Medical Sciences evaluating thrice-weekly Directly Observed Treatment, Short-Course (DOT…
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Dose Escalation Study of SQ109 in Healthy Adult Volunteers [Phase 1]
Phase 1 dose-escalation study of SQ109 in healthy adults has completed, assessing safety and tolerability for potential tuberculosis treatme…
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis [Phase 4]
A Phase 4 trial comparing immediate versus deferred initiation of antiretroviral therapy in HIV-infected adults undergoing tuberculosis trea…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment [Phase 2]
Phase 2 TB trial TBTC Study 28 comparing moxifloxacin with isoniazid for tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: TBTC NAA Study: Pilot Study of Surrogate Markers for Outcome of TB Treatment
The CDC-sponsored TBTC study evaluated surrogate markers to predict tuberculosis treatment outcomes in a completed pilot trial.
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: TBTC Study 24: Intermittent Treatment of TB With Isoniazid Resistance or Intolerance [NA]
This clinical trial update notes that TBTC Study 24, evaluating intermittent treatment strategies for tuberculosis in patients with isoniazi…