Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care Workers
A completed clinical trial comparing conversion rates of the tuberculin skin test (TST) and the QuantiFERON-TB Gold In-Tube assay in health …
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Equivalence Study of Tuberculin Purified Protein Derivative in Comparison With a Reference Standard (PPD-S2) [Phase 2]
This Phase 2 clinical trial update evaluates equivalence of tuberculin purified protein derivative (PPD-S2) against a reference standard for…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Evaluation Of The Performance Of The Nitrate Reductase And Resazurin Titre Assay For The Detection of Mycobacterium Tuberculosis Complex From Sputum In A High Tb and Hiv Setting
A completed clinical trial evaluating the nitrate reductase and resazurin titre assay for detecting Mycobacterium tuberculosis complex in sp…
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CLINICAL_TRIALS trial_result · 2013-01-31Clinical Trial Update: Preliminary Evaluation of a Point-Of-Care Liver Function Test [NA]
This completed clinical trial evaluates a point-of-care liver function test for detecting drug-induced liver injury in individuals with HIV …
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Clinical Trial to Investigate the Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI® Following One Month of Isoniazid Treatment in Subjects With Latent Tuberculosis Infection [Phase 2]
A Phase 2 clinical trial completed to evaluate the safety, tolerability, and immunogenicity of the RUTI tuberculosis vaccine after one month…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Effect of Weight and/or Obesity on Ethambutol Drug Concentrations [Phase 4]
Phase 4 clinical trial investigating how weight and obesity affect ethambutol drug concentrations has completed with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: A Safety and Dose Finding Trial of C-Tb, When Given to Adult Patients Recently Diagnosed With Active Tuberculosis [Phase 1]
Phase 1 safety and dose-finding study of C-Tb in adult patients recently diagnosed with active tuberculosis; the trial has completed.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Safety and Risk of Sensitisation of the rdESAT-6 + rCFP-10 Skin Test Following Repeated Intradermal Administration [Phase 1]
Phase 1 trial update assessing safety and potential sensitisation risk of repeated intradermal administration of the rdESAT-6 + rCFP-10 skin…
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis(TB) Subunit Vaccine [Phase 1]
Phase 1 safety and immunogenicity data for an adjuvanted tuberculosis subunit vaccine have been reported as completed. The trial was sponsor…
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Trial on the Safety of a New Liposomal Adjuvant System, CAF01, When Given With the Tuberculosis Subunit Vaccine Ag85B-ESAT-6 as Two Injections With Two Months Interval to Healthy Adult Volunteers [Phase 1]
A Phase 1 safety study evaluating the CAF01 liposomal adjuvant with the tuberculosis subunit vaccine Ag85B-ESAT-6 in healthy adult volunteer…
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis (TB) Subunit Vaccine in Purified Protein Derivative (PPD) Positive Volunteers [Phase 1]
Phase 1 safety and immunogenicity study of an adjuvanted tuberculosis subunit vaccine in PPD-positive volunteers has completed.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: A Trial of the C-Tb Skin Test, When Given Intradermally to Healthy Volunteers Previously Vaccinated With BCG [Phase 2]
A Phase 2 trial assessed the intradermal C-Tb skin test in healthy adults previously vaccinated with BCG; the study status is completed.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Pharmacogenetics of Vitamin D Supplementation in Tuberculosis [Phase 3]
Phase 3 trial assessing pharmacogenetics of vitamin D supplementation in tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2012-12-24Clinical Trial Update: Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care Setting [NA]
Completed clinical trial from the University of Cape Town evaluating sputum induction and novel technologies to improve tuberculosis diagnos…
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CLINICAL_TRIALS trial_result · 2012-11-27Clinical Trial Update: Comparison of the Effect Between Levofloxacin and Moxifloxacin Among MDR-TB Patients [Phase 3]
A Phase 3 trial comparing levofloxacin and moxifloxacin in multidrug-resistant tuberculosis was terminated.
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: Using Entecavir to Reduce Hepatitis in Highly Viremic HBV Patients During Anti-tuberculous Treatment [Phase 4]
Phase 4 clinical trial update evaluating whether entecavir can reduce hepatitis in highly viremic hepatitis B patients undergoing anti-tuber…
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CLINICAL_TRIALS trial_result · 2012-10-22Clinical Trial Update: Tuberculosis Prevention for HIV Infected Adults [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating tuberculosis prevention in adults living with HIV.
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection [Phase 3]
Phase 3 trial evaluating three months of weekly rifapentine and isoniazid for preventing tuberculosis after M. tuberculosis infection has co…
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CLINICAL_TRIALS trial_result · 2012-09-26Clinical Trial Update: Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa [NA]
A clinical trial update reports on the feasibility of a lateral flow urine LAM test to diagnose tuberculosis in South Africa.
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity
Completed clinical trial evaluating anti-tuberculosis drug levels and their correlation with drug-induced hepatotoxicity. The study aimed to…
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CLINICAL_TRIALS trial_result · 2012-08-30Clinical Trial Update: A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A [Phase 1]
This completed Phase 1 study evaluated anti-mycobacterial immune responses induced by BCG and the candidate TB vaccine MVA85A using a BCG ch…
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: Vitamin D Supplementation Enhances Immune Response to Bacille-Calmette-Guerin (BCG) Vaccination in Infants [NA]
A completed clinical trial suggests vitamin D supplementation may enhance the immune response to Bacille Calmette-Guérin vaccination in infa…
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CLINICAL_TRIALS trial_result · 2012-08-16Clinical Trial Update: Study of AERAS 422 in Healthy Adults [Phase 1]
The Phase 1 study of the TB vaccine candidate AERAS 422 in healthy adults has completed.
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis [Phase 2]
A Phase 2 clinical trial update evaluating bactericidal activity of multiple oral doses of bedaquiline (TMC207) in adults with sputum smear-…
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer [Phase 1]
Phase 1 interaction study evaluating bedaquiline (TMC207) with lopinavir/ritonavir in healthy volunteers. The study has completed.