Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects [Phase 1]
Phase 1 study evaluating the effect of food on the bioavailability and pharmacokinetics of PA-824 (pretomanid) tablets in healthy adult subj…
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: Promoting Adherence to TB Regimens in Latino Adolescents
The trial update reports that the study evaluating strategies to promote adherence to tuberculosis treatment in Latino adolescents has compl…
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. [Phase 4]
Phase 4 trial results from Denmark assessing whether BCG vaccination at birth influences childhood morbidity.
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: Tuberculosis in a Multiethnic Inner City Population
This ClinicalTrials.gov update reports the completion of a study led by NYU Langone Health examining tuberculosis in a multiethnic inner-cit…
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CLINICAL_TRIALS trial_result · 2015-12-24Clinical Trial Update: Antiretroviral Therapy and Inflammatory and Coagulation Biomarkers: iMACS Study
Update on the iMACS trial evaluating antiretroviral therapy and its effects on inflammatory and coagulation biomarkers; the study has comple…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Behavioral Interventions for Control of TB
A completed Columbia University–sponsored clinical trial evaluating behavioral interventions to control tuberculosis.
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Universal Screening for Tuberculosis and Anemia With the CHICA System [NA]
The CHICA system study on universal screening for tuberculosis and iron-deficiency anemia has completed, with results posted on 2015-12-18.
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study
This completed multicenter trial provides updated data on the epidemiology and diagnosis of haemoptysis and its associations with several pu…
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: The Utility of Intensified Case Finding Combined With a Package of Novel TB Diagnostics Using a Mobile Clinic in Africa [NA]
A completed clinical trial evaluating intensified case finding and a package of novel TB diagnostics delivered via a mobile clinic in Africa…
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg [Phase 4]
A Phase 4 randomized trial evaluating the concomitant use of rifampicin and efavirenz for TB and HIV co-infection was terminated.
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CLINICAL_TRIALS trial_result · 2015-11-05Clinical Trial Update: Alere Mycobacterium Tuberculosis Urine Study
The Alere Mycobacterium Tuberculosis Urine Study has completed its clinical trial (NCT01585532) evaluating a TB urine test.
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Leukapheresis Sampling for Immune Responses After BCG Vaccination in BCG-naïve Healthy Adults in the US [EARLY_Phase 1]
Phase 1 trial update on leukapheresis sampling to study immune responses after BCG vaccination in BCG-naive healthy adults in the United Sta…
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of an MVA85A prime vaccination followed by BCG boost for tuberculosis in individuals with…
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485) [Phase 2]
A Phase 2 study assessing the efficacy against tuberculosis, safety, and immunogenicity of the MVA85A/AERAS-485 vaccine in HIV-infected adul…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) [NA]
A completed clinical trial focused on improving the diagnosis of tuberculosis in HIV-infected children in Asia and Africa. The study was con…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Study of AERAS-402 in Healthy Infants [Phase 1, Phase 2]
AERAS-402, a tuberculosis vaccine candidate, was tested in healthy infants in Phase 1/Phase 2, with the study completed and results posted.
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CLINICAL_TRIALS trial_result · 2015-07-03Clinical Trial Update: Treatment Duration for Abdominal Tuberculosis [Phase 3]
A Phase 3 trial evaluating the duration of therapy for abdominal tuberculosis has completed, with ClinicalTrials.gov listing status as COMPL…
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) [Phase 3]
Phase 3 TEMPRANO trial in HIV-infected adults evaluated initiating antiretroviral therapy early and/or starting isoniazid prophylaxis early …
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: A Trial of the Urine LAM Strip Test for TB Diagnosis Amongst Hospitalized HIV-infected Patients [NA]
This entry reports that a clinical trial evaluating the urine LAM strip test for tuberculosis diagnosis in hospitalized HIV-infected patient…
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Adjunct Immunotherapy With Immunoxel in Patients With TB and TB/HIV [Phase 3]
A Phase 3 trial evaluating adjunct Immunoxel immunotherapy in tuberculosis patients, including those coinfected with HIV, has completed.
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: An Evaluation of the Pharmacological Interaction of Lopinavir/r and Rifampin [Phase 4]
A Phase 4 study evaluating the pharmacological interaction between lopinavir/ritonavir and rifampin has completed.
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CLINICAL_TRIALS trial_result · 2015-04-17Clinical Trial Update: A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB) [Phase 2]
Phase 2 study evaluating intradermal administration of the C-Tb skin test in adults recently diagnosed with active tuberculosis; the trial s…
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CLINICAL_TRIALS trial_result · 2015-04-17Clinical Trial Update: A Safety and Immunogenicity Trial With an Adjuvanted TB Subunit Vaccine (Ag85B-ESAT-6 + IC31) [Phase 1]
Phase 1 safety and immunogenicity results for an adjuvanted tuberculosis subunit vaccine (Ag85B-ESAT-6 with IC31) have been completed.
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CLINICAL_TRIALS trial_result · 2015-04-17Clinical Trial Update: Comparison of Diagnostic Performance of C-Tb to QuantiFERON®-TB, in Combination With a Safety Assessment of C-Tb vs Tuberculin PPD RT23 SSI [Phase 3]
Phase 3 trial assessing the diagnostic performance of the C-Tb skin test compared with QuantiFERON-TB, with a safety comparison of C-Tb agai…
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CLINICAL_TRIALS trial_result · 2015-04-17Clinical Trial Update: Safety Study Investigating if Concomitant Injections of C-Tb and 2 T.U Tuberculin Affect Induration Responses [Phase 2, Phase 3]
A completed Phase 2/3 safety study evaluating whether concomitant injections of C-Tb and 2 tuberculin units affect induration responses.