Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: TMC207 +/- Rifabutin/Rifampin [Phase 1]
Phase 1 study evaluating bedaquiline (TMC207) with or without rifabutin or rifampin in tuberculosis has completed. The update notes the tria…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis [Phase 2]
A Phase 2 trial evaluating rifapentine plus moxifloxacin for pulmonary tuberculosis was terminated. Results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Linkage and Retention: A Randomized Trial to Optimize HIV/TB Care in South Africa [NA]
A randomized trial completed in South Africa aimed at improving linkage to care and retention for individuals with HIV/TB co-infection.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Whole Blood Bactericidal Activity Against Mycobacterium Tuberculosis of Pyrazinamide Plus Allopurinol in Healthy Volunteers [Phase 1]
Phase 1 study evaluating the bactericidal activity of pyrazinamide in combination with allopurinol against Mycobacterium tuberculosis in hea…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Evaluating Celecoxib Activity in Mycobacterium Tuberculosis: A Whole Blood Bactericidal Activity Study in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating whether celecoxib exhibits whole-blood bactericidal activity against tuberculosis in healthy volunteers; the study …
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers [Phase 1]
A Phase 1 study evaluating whole blood bactericidal activity of rifampicin against Mycobacterium tuberculosis in healthy volunteers. The tri…
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers [Phase 1]
Phase 1 trial in healthy volunteers evaluating the whole blood bactericidal activity of a combination of faropenem and amoxicillin/clavulani…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Essentiality of INH in TB Therapy [Phase 2]
This Phase 2 clinical trial update evaluates the essential role of isoniazid (INH) in tuberculosis therapy.
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Dose-Escalation Study to Evaluate the Safety and Immunogenicity of MTBVAC Vaccine in Comparison With BCG Vaccine. [Phase 1]
Phase 1 dose-escalation study comparing the safety and immunogenicity of the MTBVAC vaccine to the BCG vaccine has completed, with results p…
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 [Phase 2]
A Phase IIb clinical study evaluating the recombinant Mycobacterium tuberculosis allergen ESAT6-CFP10 for tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana [Phase 2]
Phase 2 clinical trial investigating concomitant infections of Mansonella perstans in patients with tuberculosis and Buruli ulcer disease in…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Quality of Tuberculosis Care in Urban Patna, India [NA]
A completed clinical trial evaluating the quality of tuberculosis care in urban Patna, India.
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65 [Phase 2]
A Phase IIb trial evaluating the recombinant Mycobacterium tuberculosis allergen ESAT6-CFP10 in healthy adults aged 18-65 has completed.
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Comparative Study of Bacille Calmette Guerin (BCG) Delivery Via Disposable Syringe Jet Injector and Needle & Syringe [NA]
A PATH-sponsored clinical trial compared Bacille Calmette-Guérin (BCG) vaccine delivery by a disposable syringe jet injector versus the trad…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Safety and Immunogenicity Study of GSK Biologicals Tuberculosis Vaccines (692342) to Healthy Adults [Phase 2]
Phase 2 safety and immunogenicity trial of GSK tuberculosis vaccines in healthy adults completed; results posted.
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Tuberculosis Recurrence Upon Treatment With Highly Active Antiretroviral Therapy
A completed CAPRISA study examines tuberculosis recurrence in people receiving highly active antiretroviral therapy (ART) for HIV in South A…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB Disease [Phase 2]
Phase 2 trial assessing safety and immunogenicity of a candidate TB vaccine in adults with tuberculosis has been terminated with results pos…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: A Study for Safety and Immunogenicity of BCG and AERAS-404 in HIV-Negative, TB-Negative, BCG-Naive Adults [Phase 1]
This Phase 1 trial assessed the safety and immunogenicity of BCG and the AERAS-404 TB vaccine in HIV-negative, TB-negative, BCG-naive adults…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Reactogenicity, Safety and Immunogenicity of a TB/FLU-01L Tuberculosis Vaccine [Phase 1]
This document reports the results of a Phase 1 trial evaluating the reactogenicity, safety, and immunogenicity of the TB/FLU-01L tuberculosi…
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccination [Phase 1]
Phase 1 study evaluating pre-clearance of latent tuberculosis infection and revaccination with the BCG vaccine.
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents [Phase 2]
Phase 2 trial assessing safety and immunogenicity of a TB vaccine candidate in healthy HIV-negative adolescents; results posted after comple…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults. [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of a TB vaccine candidate in HIV-positive adults; results available.
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Heterologous Effects of BCG in Healthy UK Adults [NA]
Completed clinical trial from the University of Oxford assessing non-specific (heterologous) immune effects of the BCG vaccine in healthy UK…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Pharmacokinetics and Safety of Moxifloxacin [Phase 4]
A Phase 4 trial evaluating the pharmacokinetics and safety of moxifloxacin for tuberculosis was terminated.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Intensifying Multi-Drug Resistant Tuberculosis Contact Tracing by Social Network Analysis
A completed clinical trial from Oxford University Clinical Research Unit in Vietnam examining intensified contact tracing for multidrug-resi…