Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Test and Treat TB: A Proof of Concept Trial in South Africa [NA]
The document reports the completion of the Test and Treat TB proof-of-concept trial in South Africa, sponsored by Massachusetts General Hosp…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: A Blinded, Cross-sectional, Diagnostic Evaluation Study Performed in Pulmonary TB Suspects at the TB Dispensary for Sector 4 of the Marius-Nasta-Institute in Bucharest, Romania
This document reports a completed clinical trial update. It describes a blinded, cross-sectional diagnostic evaluation study conducted among…
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CLINICAL_TRIALS trial_result · 2018-02-13Clinical Trial Update: Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV [Phase 2]
Phase 2 trial comparing rifampin-based versus rifabutin-based tuberculosis treatment in people with HIV; study terminated with results poste…
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone [Phase 3]
A Phase 3 randomized, placebo-controlled trial evaluating prednisone to prevent TB-IRIS in high-risk HIV patients undergoing antiretroviral …
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Evaluation of Non-Inferiority of Two Fast Follower Nucleic Acid Amplification Tests
A completed trial evaluated whether two rapid nucleic acid amplification tests are non-inferior to a reference test for detecting tuberculos…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Cell Phone Messaging to Improve Communication of Critical Laboratory Results to Patients in Rural Uganda [NA]
A completed clinical trial evaluating whether cell phone messaging can improve patient communication of critical lab results in rural Uganda…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Pharmacokinetic Issues of Moxifloxacin Plus Rifapentine [Phase 1]
Phase 1 study assessing pharmacokinetic interactions between moxifloxacin and rifapentine for tuberculosis, which has been terminated.
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Doxycycline in Human Pulmonary Tuberculosis [Phase 2]
Phase 2 trial evaluating doxycycline for pulmonary tuberculosis has completed. The snippet does not provide efficacy or safety results.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study) [Phase 4]
This Phase 4 pharmacokinetic study evaluated optimal dosing of first-line tuberculosis and antiretroviral drugs in children and has complete…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia [NA]
This completed clinical trial from Brigham and Women's Hospital evaluates the effectiveness of alcohol interventions among tuberculosis pati…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosis [Phase 3]
A Phase 3 randomized trial compared intensive smoking-cessation support to standard smoking-cessation advice in smear-positive pulmonary tub…
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CLINICAL_TRIALS trial_result · 2017-09-07Clinical Trial Update: Efficacy of Nyaditum Resae(R) Against Active TB in Georgia [Phase 2, Phase 3]
Clinical trial update for Nyaditum Resae showing Phase 2/3 evaluation in close contacts of active tuberculosis; current status is unknown.
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Quality of Tuberculosis Care in Mumbai, India [NA]
McGill University-sponsored clinical trial evaluating quality of tuberculosis care in Mumbai, India has completed.
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Screening for TB in Pregnancy. on HIV-Infected Pregnant Women [NA]
The clinical trial evaluating tuberculosis screening in HIV-infected pregnant women has completed. The update does not include trial results…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Innovative Approaches to Tuberculosis Control
This clinical trial update describes Johns Hopkins University's study on innovative approaches to tuberculosis control, which has completed.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) [EARLY_Phase 1]
A completed Phase 1 study evaluating whether crushing bedaquiline 400 mg provides bioequivalent exposure to the tablet form under fed condit…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Impact of Nursing Interventions on Adherence to Treatment With Anti-tuberculosis Drugs in Children and Adolescents [NA]
This completed clinical trial evaluated the impact of nursing interventions on adherence to anti-tuberculosis treatment in children and adol…
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Trial of High-Dose Rifampin in Patients With TB [Phase 2]
Phase 2 trial assessing high-dose rifampin in patients with tuberculosis has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Iron Absorption and Utilization During Tuberculosis and After Treatment
A clinical trial update describing iron absorption and utilization in people with tuberculosis during infection and after completion of TB t…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02A in Healthy PPD-positive Adults [Phase 2]
Phase 2 trial evaluating the safety and immunogenicity of GlaxoSmithKline's TB vaccine candidate Mtb72F/AS02A in healthy PPD-positive adults…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults. [Phase 1]
A Phase 1 study reports on the safety and immunogenicity of GlaxoSmithKline's TB vaccine candidate Mtb72F/AS02 in healthy PPD-negative adult…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TB [Phase 4]
Phase 4 pharmacokinetics study evaluating boosted Lopinavir/ritonavir dosing in infants and young children co-infected with HIV and tubercul…
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB) [Phase 1]
Phase 1 study reporting the bioavailability of rifampicin in fixed-dose combinations widely used in South Africa for drug-susceptible tuberc…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Virtual Observed Therapy for Patients With Tuberculosis [NA]
The document reports the completion of a clinical trial evaluating virtual observed therapy for tuberculosis. The study explored using virtu…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosis
Completed clinical trial evaluating PCR on DNA extracted from slides and filter paper for detection of tuberculosis and multidrug-resistant …