Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection [Phase 3]
Completed Phase 3 open-label study comparing dolutegravir and efavirenz for HIV/TB co-infection; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case Finding
This cluster-randomized trial comparing DOTS to DOTS Plus active case finding for tuberculosis has completed. The snippet does not report tr…
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CLINICAL_TRIALS trial_result · 2019-01-10Clinical Trial Update: TB Host Directed Therapy [Phase 2]
Phase 2 clinical trial update for a host-directed therapy targeting tuberculosis.
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CLINICAL_TRIALS trial_result · 2018-12-31Clinical Trial Update: Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis [Phase 3]
Phase 3 trial comparing raltegravir to efavirenz in ART-naive HIV-1 patients on rifampin for active tuberculosis; completed status ongoing r…
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: The Correlate of Risk Targeted Intervention Study [Phase 2, Phase 3]
A trial update for a Phase 2/Phase 3 study on a targeted intervention for tuberculosis, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB) [Phase 3]
Phase 3 clinical trial BRIEF TB evaluating rifapentine-isoniazid for tuberculosis prevention has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Healthy Infants [Phase 2]
Phase 2 safety and immunogenicity study of a tuberculosis vaccine candidate in healthy infants completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women [Phase 4]
Phase 4 trial comparing immediate versus deferred isoniazid preventive therapy in HIV-infected pregnant women; study completed with results …
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Phase 2a EBA Trial of AZD5847 [Phase 2]
Phase 2a trial update for AZD5847 in tuberculosis completed.
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: PK Study of Rifampicin Interactions With DMPA and Efavirenz in TB [Phase 2]
Phase 2 trial updating pharmacokinetics of rifampicin interactions with Depo-Provera (DMPA) and efavirenz in HIV and TB patients; completed …
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults [Phase 2]
Phase 2 safety and immunogenicity trial of a tuberculosis vaccine candidate in HIV-positive adults completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults [Phase 4]
Phase 4 trial evaluating how HIV infection and active tuberculosis affect immune responses to the trivalent influenza vaccine in adults.
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Safety and Immunogenicity of 2 Formulations of Tuberculosis Vaccine GSK692342 Given at 0,1 Months to Healthy Adults [Phase 2]
Phase 2 trial assessing safety and immunogenicity of two formulations of the TB vaccine GSK692342 in healthy adults.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics and ex-vivo antitubercular activity of the PBTZ169 formulation has completed…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis [Phase 3]
Phase III trial evaluating Vaccae™ for prevention of tuberculosis has completed; the update does not include specific efficacy or safety res…
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India
Completed trial assessing dietary intake and the prevalence of refeeding syndrome among high-risk tuberculosis patients in Chhattisgarh, Ind…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing MTBVAC to BCG in newborns with a safety arm in adults to evaluate safety and immunogenicity for tubercu…
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa [Phase 2]
Phase 2 trial evaluating the safety and immunogenicity of the VPM1002 vaccine versus BCG in HIV-exposed and unexposed newborns in South Afri…
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen for Children [Phase 3]
This update notes the completion of a Phase 3 trial evaluating a recombinant ESAT6-CFP10 allergen for diagnosing tuberculosis in children.
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen [Phase 3]
A Phase 3 clinical study evaluating a recombinant ESAT6-CFP10 allergen for tuberculosis has completed, according to ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants [Phase 1, Phase 2]
This update confirms completion of a Phase 1/2 study evaluating the safety and immunogenicity of the AERAS-404 vaccine in BCG-primed infants…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Tuberculosis in China
This entry notes the completion of a National Institute of Allergy and Infectious Diseases study conducted in China focused on tuberculosis.…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Gene Expression in HIV and Tuberculosis Co-infection
The document reports a completed clinical trial update from NIAID examining gene expression in HIV and tuberculosis co-infection.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali
The terminated trial assessed the MODS test for diagnosis of multidrug-resistant tuberculosis and for second-line antituberculous drug susce…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Multi-Drug Resistant Tuberculosis in Korea
A completed clinical trial update investigating multi-drug resistant tuberculosis in Korea.