Treatment-resistant Depression
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CLINICAL_TRIALS withdrawal · 2026-03-04Clinical Trial Update: N2O for Acute Suicidality and Depression in the ED [Phase 2]
A Phase 2 clinical trial evaluating nitrous oxide for acute suicidality and major depressive disorder in the emergency department has been w…
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CLINICAL_TRIALS withdrawal · 2026-01-21Clinical Trial Update: NESBID: Neuro-Stimulation of the Brain in Depression [NA]
NESBID, a trial of neuro-stimulation for depression, has been withdrawn. The study involved transcranial direct current stimulation for majo…
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CLINICAL_TRIALS withdrawal · 2026-01-12Clinical Trial Update: Low-Intensity Focused Ultrasound for Treatment-Resistant Depression [NA]
Trial evaluating low-intensity focused ultrasound for treatment-resistant depression has been suspended.
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CLINICAL_TRIALS withdrawal · 2024-05-03Clinical Trial Update: First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) [Phase 1]
The first-in-human single ascending dose study of FluoroEthylNorMemantine (FENM) by ReST Therapeutics has been withdrawn; the listed conditi…
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CLINICAL_TRIALS withdrawal · 2022-08-10Clinical Trial Update: Olanzapine Augmentation Therapy in Treatment-resistant Depression: a Double-blind Placebo-controlled Trial [Phase 3]
Phase 3 trial of olanzapine augmentation for treatment-resistant depression was withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-08-05Clinical Trial Update: ECT vs. Esketamine [Phase 3]
A Phase 3 clinical trial comparing electroconvulsive therapy (ECT) versus esketamine for treatment resistant depression and major depressive…
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CLINICAL_TRIALS withdrawal · 2019-12-18Clinical Trial Update: Neural and Antidepressant Effects of Propofol (Phase 2) [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial examining neural and antidepressant effects of propofol for treatment resistant depression has been withdra…
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CLINICAL_TRIALS withdrawal · 2018-08-06Clinical Trial Update: Deep Brain Stimulation to Relieve Depression [Phase 3]
Phase 3 clinical trial of deep brain stimulation for treatment resistant depression was withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-02-17Clinical Trial Update: Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy [NA]
This clinical trial update reports the withdrawal of a Kaiser Permanente study evaluating ultrabrief right unilateral and brief-pulse electr…
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CLINICAL_TRIALS withdrawal · 2016-01-05Clinical Trial Update: e-PAT Neuromod Evaluation of Personalized rTMS for Resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating personalized e-PAT neuromodulation with repetitive transcranial magnetic stimulation for treatment-resis…
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CLINICAL_TRIALS withdrawal · 2011-06-06Clinical Trial Update: Ketamine Frequency Treatment for Major Depressive Disorder [Phase 4]
A Phase 4 clinical trial investigating a ketamine frequency treatment for major depressive disorder has been withdrawn.