Treatment-resistant Depression
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CLINICAL_TRIALS trial_result · 2022-04-21Clinical Trial Update: Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression: OL Cohort [NA]
Clinical trial update for Stanford's OL Cohort of Accelerated Intelligent Neuromodulation Therapy in treatment-resistant depression has comp…
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial. [Phase 3]
Phase 3 randomized controlled trial evaluating simvastatin as an augmentation therapy for treatment resistant depression and major depressiv…
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CLINICAL_TRIALS trial_result · 2021-07-26Clinical Trial Update: An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients [Phase 2]
Phase 2 clinical trial evaluating AXS-05 for treatment-resistant depression in treatment-adherent patients.
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CLINICAL_TRIALS trial_result · 2021-07-22Clinical Trial Update: Psilocybin in Depression Resistant to Standard Treatments [Phase 2]
Phase 2 clinical trial update evaluating psilocybin for treatment-resistant depression.
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: Cannabidiol for Treatment Resistant Depression [Phase 4]
Phase 4 clinical trial evaluating cannabidiol for treatment resistant depression was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression [Phase 2]
Phase 2 proof-of-concept study evaluating MIJ821 for treatment-resistant depression has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD) [NA]
A completed clinical trial update for SAINT-TRD (Stanford Accelerated Intelligent Neuromodulation Therapy) investigating treatment-resistant…
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder [Phase 3]
Phase 3 trial assessing efficacy and safety of AXS-05 in treatment-resistant major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD [Phase 2]
Phase 2 trial update for REL-1017 in major depressive disorder shows safety, tolerability, pharmacokinetics, and symptom response with 7-day…
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CLINICAL_TRIALS trial_result · 2020-11-09Clinical Trial Update: The UTHealth Ketamine Project [Phase 2]
Phase 2 trial update for the UTHealth Ketamine Project in treatment-resistant depression and major depressive disorder (terminated with resu…
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CLINICAL_TRIALS trial_result · 2020-10-23Clinical Trial Update: Neuroimaging in Patients Undergoing TMS for Depression [NA]
Completed clinical trial evaluating neuroimaging in patients undergoing Transcranial Magnetic Stimulation for treatment-resistant depression…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression [Phase 2]
Phase 2 study in Japanese participants evaluated fixed-dose intranasal esketamine for treatment-resistant depression; the trial completed an…
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CLINICAL_TRIALS trial_result · 2020-08-31Clinical Trial Update: Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients [Phase 2]
Phase 2 clinical trial update evaluating low dose intravenous ketamine for treatment-resistant depression has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-11-20Clinical Trial Update: Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent [Phase 2]
Phase 2 trial update investigating the efficacy of deep anesthesia with isoflurane as a fast-response antidepressant agent.
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Evaluation of Schemes of Administration of Intravenous Ketamine in Depression [Phase 3]
A Phase 3 clinical trial evaluating different schemes of intravenous ketamine administration for treatment-resistant depression is ongoing/u…
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression [NA]
A completed clinical trial evaluating subanesthetic ketamine plus electroconvulsive treatment for treatment resistant depression.
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression [Phase 3]
This Phase 3 trial evaluated intranasal esketamine plus an oral antidepressant for relapse prevention in adults with treatment-resistant dep…
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression [Phase 3]
A Phase 3 long-term safety and efficacy study of intranasal esketamine for treatment-resistant depression has completed, with results posted…
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CLINICAL_TRIALS trial_result · 2019-04-24Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression [Phase 3]
Phase 3 study evaluated intranasal esketamine plus an oral antidepressant in elderly patients with treatment-resistant depression; results w…
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression [Phase 3]
Phase 3 study evaluating the efficacy, safety, and tolerability of flexible doses of intranasal esketamine in combination with an oral antid…
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CLINICAL_TRIALS trial_result · 2019-04-18Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression [Phase 3]
Phase 3 trial results evaluate fixed-dose intranasal esketamine plus an oral antidepressant in adults with treatment-resistant depression; r…
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: Pharmacogenomics for Antidepressant Guidance and Education
Clinical trial on pharmacogenomics for antidepressant guidance and education in treatment-resistant depression was terminated with results p…
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Low Field Magnetic Stimulation for Treatment Resistant Depression [NA]
A completed clinical trial investigating low field magnetic stimulation for treatment resistant depression, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-12Clinical Trial Update: Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD) [NA]
Clinical trial update for deep brain stimulation in treatment-resistant depression shows completed status with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: Monocentric Pilot Study, for a Randomized, Crossover, Blinded Trial: Comparison of the Therapeutic Efficacy of Low Frequency Repeated Transcranial Magnetic Stimulation on Cortical Area 9 Compared to Brodmann Area 46 in the Treatment of Depressive Disorders. [Phase 2]
Phase 2 randomized, crossover, blinded trial comparing low-frequency rTMS over cortical area 9 vs Brodmann area 46 for resistant depressive …