Treatment-resistant Depression
📧 Sign up to get email alerts when something new happens for Treatment-resistant Depression.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-07-29Clinical Trial Results: Personalized Therapeutic Neuromodulation for Anhedonic Depression [NA]
A completed clinical trial evaluating personalized therapeutic neuromodulation for treatment-resistant depression has posted results.
-
CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression [Phase 4]
Phase 4 clinical trial update evaluating algorithm-guided treatment versus treatment as usual for treatment resistant depression is currentl…
-
CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) I [Phase 1]
Phase 1 trial SWIP I tested whether slow-wave induction by propofol could treat treatment-resistant depression. The study has completed and …
-
CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Accelerated Theta Burst in Treatment-Resistant Depression: A Dose Finding and Biomarker Study [NA]
Results have been posted for a dose-finding and biomarker study evaluating accelerated theta burst stimulation in treatment-resistant depres…
-
CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression [Phase 4]
Phase 4 clinical trial assessing oral aspirin plus ketamine as an adjunct to standard antidepressant therapy for treatment-resistant depress…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression [Phase 2]
Navitor Pharmaceuticals announced completion of the Phase 2 study of NV-5138 in adults with treatment-resistant depression, and the results …
-
CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Multiple Case Study of Schema Therapy for Difficult-to-treat Depression- DEPRE-ST*Case [NA]
A completed clinical trial using a multiple case study design to examine schema therapy for difficult-to-treat depression. The study status …
-
CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Adaptive tDCS for Treatment-Resistant MDD [Phase 1]
A Phase 1 adaptive transcranial direct current stimulation (tDCS) trial for treatment-resistant depression has been terminated.
-
CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Mindfulness Engaged Neurostimulation for Depression [Phase 2]
Phase 2 clinical trial of Mindfulness Engaged Neurostimulation for depression is currently active but not recruiting at University of Califo…
-
CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: KET-RO Plus RO DBT for Treatment Resistant Depression [Phase 1]
Phase 1 trial evaluating the combination of ketamine with RO-DBT for treatment-resistant depression has completed and posted results.
-
CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Minocycline as Adjunctive Treatment for Treatment Resistant Depression [Phase 3]
A Phase 3 clinical trial evaluating minocycline as an adjunctive treatment for treatment-resistant depression has completed.
-
CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Personalized Therapeutic Neuromodulation for Anhedonic Depression [NA]
This update reports the completion of a clinical trial investigating personalized neuromodulation for treatment-resistant depression.
-
CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Neurofeedback for Treatment Resistant Depression [NA]
A completed clinical trial evaluating neurofeedback as a treatment for treatment-resistant depression. The update does not include reported …
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE) [Phase 2]
An open-label Phase 2 safety study of AXS-05 in treatment-resistant depression and major depressive disorder was terminated, with results po…
-
CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD [Phase 3]
Phase 3 trial update evaluating two administrations of COMP360 (psilocybin) for treatment-resistant depression, focusing on efficacy, safety…
-
CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Multiple Ascending Dose Phase 1 Study of ALA-3000 [Phase 1]
Phase 1 multiple ascending dose study of ALA-3000 in treatment-resistant depression has completed.
-
CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation [Phase 2]
A Phase 2 clinical trial evaluating psilocybin for safety and efficacy in treatment-resistant depression with chronic suicidal ideation has …
-
CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote) [NA]
A completed pilot study examining brain reactivity to nitrous oxide in treatment-resistant depression using MRI and ultrasound imaging.
-
CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD [Phase 3]
Clinical trial update on the Phase 3 study of COMP360 for treatment-resistant depression, highlighting efficacy, safety, and tolerability in…
-
CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Nitrous Oxide for Late-Life Depression - PROTO-BRAIN [NA]
The PROTO-BRAIN study evaluating nitrous oxide for late-life depression and treatment-resistant depression has completed.
-
CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression [NA]
A completed clinical trial evaluating dose-optimized and spaced transcranial direct current stimulation for treatment-resistant depression a…
-
CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD) [NA]
This clinical trial update indicates a Mayo Clinic study evaluating transcranial direct current stimulation as an adjunctive treatment for t…
-
CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Development of Neuro-Navigated Transcranial Magnetic Stimulation (TMS) Using MRI
This update reports the completion of a clinical trial evaluating MRI-guided neuro-navigated Transcranial Magnetic Stimulation for treatment…
-
CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Virtual Neuro-Navigation System for Personalized Community Based TMS [NA]
This update reports on a completed clinical trial evaluating a virtual neuro-navigation system to guide personalized community-based transcr…
-
CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Personalized rTMS for Resistant Depression [NA]
A clinical trial update notes that a study of personalized repetitive transcranial magnetic stimulation for treatment-resistant depression h…