Transthyretin Amyloid Cardiomyopathy
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Exploratory Study Evaluating the Relevance of [68Ga]Ga-FAPI-46 for Staging and Identifying Progressing Patients With Transthyretin Cardiac Amyloidosis [Phase 2]
A Phase 2 exploratory trial update evaluating the radiotracer [68Ga]Ga-FAPI-46 for staging and identifying progressing patients with transth…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Implementation of Standardized Early Identification and Diagnosis for Transthyretin Amyloidosis (ATTR) in High-Risk Populations [NA]
AstraZeneca is implementing standardized early identification and diagnosis strategies for transthyretin amyloidosis in high-risk population…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis. [Phase 1]
Phase 1 clinical trial evaluating the distribution and effects of coramitug on amyloid deposits in heart tissue of people with transthyretin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Learn More About the Change in the Blood Levels of Transthyretin When Participants With Transthyretin Amyloidosis With Cardiomyopathy Switch From Tafamidis to Acoramidis [Phase 4]
This Phase 4 study sponsored by Bayer investigates changes in blood transthyretin levels when patients with transthyretin amyloid cardiomyop…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
A real-world study evaluating acoramidis in patients with transthyretin amyloid cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Retrospective Observational Study of Epidemiology and Outcomes in Transthyretin Amyloid Cardiomyopathy in Germany
Pfizer-sponsored retrospective observational study in Germany on the epidemiology and outcomes of transthyretin amyloid cardiomyopathy (ATTR…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
A non-interventional observational study sponsored by AstraZeneca to collect data on patients with transthyretin amyloidosis, including ATTR…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis [Phase 3]
This clinical trial update indicates that the Phase 3 study CLEOPATTRA evaluating Coramitug (NNC6019-0001) for heart failure due to transthy…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Study of ALXN2220 Versus Placebo in Adults With ATTR-CM [Phase 3]
A Phase 3 trial comparing ALXN2220 to placebo in adults with transthyretin amyloid cardiomyopathy is ongoing but currently not recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: ATTR-CM: A Multi-country, Non-interventional Disease Registry
Pfizer is conducting a multi-country, non-interventional registry for transthyretin amyloid cardiomyopathy (ATTR-CM); the study is currently…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: EFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac Amyloidosis [NA]
This clinical trial in transthyretin amyloid cardiomyopathy studies exercise and nutritional supplementation. The study status is not yet re…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
A prospective study evaluating artificial intelligence-enabled screening for transthyretin amyloid cardiomyopathy (ATTR-CM). The trial statu…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy [Phase 3]
Phase 3 study evaluating eplontersen for transthyretin reduction and long-term safety in Chinese subjects with transthyretin amyloid cardiom…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Cardiac Amyloidosis in Patients With Aortic Stenosis
A clinical trial update describes a study evaluating cardiac amyloidosis in patients with aortic stenosis. The study focuses on transthyreti…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
Clinical trial update describing a longitudinal biomarker study to determine whether TTR-stabilizing therapy affects circulating TTR amyloid…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Multimodality Cardiac Imaging for Disease Progression in ATTR-CM [NA]
Clinical trial investigating multimodality cardiac imaging to track disease progression in transthyretin-related cardiac amyloidosis (ATTR-C…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis [Phase 2]
This is a Phase 2 clinical trial update for NNC6019-0001 evaluating long-term treatment in people with transthyretin amyloid cardiomyopathy …
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: US Benchmarking Clinical Study
Sponsor eMyosound SAS reports that the US benchmarking clinical study is currently recruiting participants for conditions including heart fa…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants [Phase 3]
Open-label Phase 3 safety study of Acoramidis (AG10) in symptomatic transthyretin amyloid cardiomyopathy participants; the trial is currentl…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Phenotyping and Characterization of wtATTR-CM (TRACE 1)
Clinical trial TRACE 1 is a recruiting study that aims to phenotype and characterize wild-type transthyretin amyloid cardiomyopathy in trans…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.
An observational study sponsored by Yale University uses AI analyses of ECG, point-of-care ultrasound, and transthoracic echocardiography to…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating genistein for transthyretin amyloid cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Thailand ATTR-CM Registry
A Mahidol University–sponsored clinical trial registry entry for Transthyretin amyloid cardiomyopathy (ATTR-CM) is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Exercise Training in Transthyretin Cardiac Amyloidosis [NA]
A clinical trial is currently recruiting to evaluate the effects of exercise training in patients with transthyretin-related cardiac amyloid…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: PL_GNT01_ISR_Grant 53234273
A clinical trial update indicates that the PL_GNT01_ISR_Grant study (NCT06714019) is currently enrolling by invitation for transthyretin-rel…