Therapy-related Acute Myeloid Leukemia

• CLINICAL_TRIALS trial_result · 2026-03-06
  Clinical Trial Update: CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia [Phase 2]

  Phase 2 trial update evaluating CPX-351 in combination with glasdegib for newly diagnosed acute myeloid leukemia with myelodysplasia-related…

• CLINICAL_TRIALS trial_result · 2026-03-04
  Clinical Trial Update: BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia [Phase 2]

  A randomized Phase 2 trial (BLAST MRD AML-1) evaluates adding pembrolizumab to intensive chemotherapy as frontline therapy for acute myeloid…

• CLINICAL_TRIALS trial_result · 2025-12-23
  Clinical Trial Update: CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old [Phase 2]

  Phase 2 trial update of CPX-351 for secondary acute myeloid leukemia in patients under 60; the study is currently active but not recruiting,…

• CLINICAL_TRIALS trial_result · 2025-12-19
  Clinical Trial Update: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes [Phase 2]

  Phase 2 trial evaluating adding pomalidomide to the standard liposomal daunorubicin/cytarabine chemotherapy in newly diagnosed acute myeloid…

• CLINICAL_TRIALS trial_result · 2025-11-20
  Clinical Trial Update: VYxeoS Liposomal Italian Observational Study iN the Real Practice

  A real-world observational study in Italy evaluating Vyxeos (CPX-351) for acute myeloid leukemia and its subtypes has completed.

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• CLINICAL_TRIALS trial_result · 2025-11-05
  Clinical Trial Update: Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia [Phase 2]

  Phase 2 trial evaluating geriatric assessment and genetic profiling to personalize therapy for older adults with acute myeloid leukemia; the…

• CLINICAL_TRIALS trial_result · 2025-09-08
  Clinical Trial Update: PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML) (LAM-PIK) [Phase 2]

  Phase 2 trial of PF-05212384 (PKI-587) for therapy-related AML/MDS and de novo/relapsed or refractory AML was terminated. The update indicat…

• CLINICAL_TRIALS trial_result · 2025-03-30
  Clinical Trial Update: Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation [Phase 2]

  Phase 2 trial evaluating olaparib for relapsed/refractory IDH-mutated acute myeloid leukemia or myelodysplastic syndrome; results posted 202…

• CLINICAL_TRIALS trial_result · 2024-11-04
  Clinical Trial Update: Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia [Phase 2]

  Phase 2 trial testing nivolumab and azacitidine with or without ipilimumab for refractory/relapsed or newly diagnosed acute myeloid leukemia…

• CLINICAL_TRIALS trial_result · 2023-11-07
  Clinical Trial Update: Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies [Phase 1, Phase 2]

  Phase 1/2 clinical trial evaluating donor natural killer cells and donor stem cell transplant in high-risk myeloid malignancies; completed w…

• CLINICAL_TRIALS trial_result · 2020-06-09
  Clinical Trial Update: Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia [Phase 2]

  Phase 2 clinical trial update evaluating vosaroxin with infusional cytarabine for untreated acute myeloid leukemia; results have been posted…

• CLINICAL_TRIALS trial_result · 2016-10-24
  Clinical Trial Update: Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]

  Phase 2 trial evaluating decitabine with or without bortezomib in older adults with acute myeloid leukemia; study completed with results pos…

• CLINICAL_TRIALS trial_result · 2014-08-12
  Clinical Trial Update: Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]

  Phase 2 clinical trial assessing combination chemotherapy with dasatinib for newly diagnosed acute myeloid leukemia; completed with results …