T-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma [Phase 3]
Phase 3 clinical trial update on combination chemotherapy for newly diagnosed T-cell acute lymphoblastic leukemia or T-cell lymphoblastic ly…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: A Study of LY3039478 in Combination With Dexamethasone in Participants With T-ALL/T-LBL [Phase 1, Phase 2]
Clinical trial update for LY3039478 in combination with dexamethasone in T-ALL/T-LBL (Phase 1/Phase 2) completed with results posted in 2019…
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CLINICAL_TRIALS trial_result · 2018-12-10Clinical Trial Update: Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial evaluated whether adding lestaurtinib to standard chemotherapy improves outcomes in children with newly diagnosed acute lymp…
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FDA approval · 2018-11-29FDA Approved: ARRANON — Supplemental Application (Sandoz Inc)
The FDA approved a supplemental application for ARRANON (nelarabine) submitted by Sandoz Inc.
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FDA approval · 2018-07-03FDA Approved: ARRANON — Supplemental Application (Sandoz Inc)
The FDA approved Sandoz Inc.'s supplemental application for ARRANON (nelarabine), resulting in a labeling update for the product.
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CLINICAL_TRIALS research · 2018-06-21Clinical Trial Update: Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL [Phase 2, Phase 3]
Clinical trial update for chidamide-based targeted therapy in adult T-cell lymphoblastic leukemia/lymphoma (T-LBL/ALL), spanning Phase 2 and…
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CLINICAL_TRIALS research · 2018-06-12Clinical Trial Update: Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating chidamide, an HDAC inhibitor, as targeted therapy for adult early T-cell precursor acute lympho…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Drug Use Investigation for ARRANON G (Nelarabine) Injection 250mg
Clinical trial update reporting a drug use investigation for nelarabine (ARRANON G) injection 250 mg.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia
This completed clinical trial update reports cognitive and brain-function outcomes in children treated with methotrexate for acute lymphobla…
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CLINICAL_TRIALS withdrawal · 2016-12-20Clinical Trial Update: Salvage Therapy With Chemotherapy and Natural Killer Cells in Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma [Phase 1, Phase 2]
This terminated Phase 1/Phase 2 trial studied salvage therapy combining chemotherapy and natural killer (NK) cell therapy for relapsed or re…
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CLINICAL_TRIALS research · 2016-07-11Clinical Trial Update: Gene Expression in Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
A completed study analyzing gene expression in samples from patients with T-cell acute lymphoblastic leukemia, sponsored by the Children's O…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
The trial has completed data collection and reports on samples from patients with T-cell acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Biomarker Study in Bone Marrow Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
An update on a biomarker study analyzing bone marrow samples from patients with T-cell acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying RNA in Samples From Younger Patients With T-Cell Acute Lymphoblastic Leukemia
This clinical trial update describes RNA studies using samples from younger patients with T-cell acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate
This clinical trial update summarizes how young patients with acute lymphoblastic leukemia responded to or developed resistance to methotrex…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
Clinical trial update on memory T-cell infusion after TCR-alpha/beta depleted hematopoietic stem cell transplantation, with Phase 1/2 status…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma [Phase 1]
This Phase 1 study evaluated a multi-drug regimen of temsirolimus, dexamethasone, mitoxantrone, vincristine, and pegaspargase in pediatric p…
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FDA approval · 2015-06-04FDA Approved: ARRANON — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for ARRANON (nelarabine) from Sandoz Inc. Nelarabine is indicated for T-cell acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013) [Phase 1]
Phase 1 trial of a Notch signaling pathway inhibitor (MK-0752) in T-cell acute lymphoblastic leukemia/lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia [Phase 1]
Phase 1 study of RO4929097, a gamma-secretase inhibitor, in pediatric patients with relapsed or refractory solid tumors, CNS tumors, lymphom…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pilot study evaluating donor-derived natural killer cell infusions for refractory non-B lineage hematologic cancers and solid tumors…
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Hyper-CVAD Treatment of Adult T-cell Acute Lymphoblastic Leukemia in Sweden.
A completed clinical trial in Sweden evaluated the Hyper-CVAD chemotherapy regimen for adults with T-cell acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: 506U78 in Treating Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma [NA]
Clinical trial update on the use of 506U78 for relapsed or refractory T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma;…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [NA]
Completed clinical trial evaluating a combination chemotherapy regimen for newly diagnosed pediatric acute lymphoblastic leukemia, including…
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CLINICAL_TRIALS research · 2012-10-24Clinical Trial Update: Pharmacokinetic Study of Forodesine in Children With Relapsed or Refractory T-cell or B-cell Precursor Acute Lymphoblastic Leukaemia or T-cell Non- Hodgkin's Lymphoma. [Phase 1, Phase 2]
Terminated Phase 1/2 pharmacokinetic study of forodesine in children with relapsed or refractory T-cell or B-cell precursor acute lymphoblas…