T-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL [Phase 2]
A Phase 2 clinical trial evaluating daratumumab for chemotherapy-refractory minimal residual disease in T-cell acute lymphoblastic leukemia …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) [Phase 1]
Phase 1 clinical trial of CD123-directed T-cell therapy for acute myeloid leukemia and related hematologic diseases is currently recruiting …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) [Phase 2]
A Phase 2 pediatric trial is evaluating adding dasatinib or venetoclax to initial therapy to improve responses in newly diagnosed T-cell acu…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of venetoclax and vincristine in adults with relapsed or refractory B- or T-cell acute lymphoblas…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Venetoclax and Decitabine in R/R T-ALL [Phase 2]
Phase 2 clinical trial of venetoclax and decitabine for relapsed/refractory T-cell acute lymphoblastic leukemia is currently recruiting at S…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Low-dose Chidamide Maintenance Therapy After Allo-HSCT for T-cell Acute Lymphoblastic Leukemia or T-cell Lymphomas [Phase 2]
Phase 2 trial evaluating low-dose chidamide as maintenance therapy after allogeneic hematopoietic stem cell transplantation in T-cell acute …
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Phase II Study to Evaluate Safety and Efficacy of CB-103 With Venetoclax in Adolescent and Young Adult Patients With Relapsed/Refractory T-ALL or T-LBL [Phase 2]
Phase II trial evaluating the safety and efficacy of CB-103 in combination with Venetoclax for relapsed/refractory T-cell acute lymphoblasti…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: A Phase 1 Study of of Anti-CD7 Allogeneic CAR-T Cell Therapy (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBL [Phase 1]
This report summarizes the completion of a Phase 1 study of WU-CART-007, an allogeneic anti-CD7 CAR-T cell therapy, in patients with relapse…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies [Phase 1]
Phase 1 trial evaluating anti-CD7 CAR-T cell therapy for relapsed/refractory CD7-positive T-cell malignancies has completed, assessing safet…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Venetoclax Based Regimen for R/R T-ALL [Phase 2]
Phase 2 trial evaluating a venetoclax-based regimen for relapsed/refractory T-cell acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: XmAb18968 (CD3-CD38) in Relapsed or Refractory Acute Leukemia and T Cell Lymphoblastic Leukemia [Phase 1]
Phase 1 trial of XmAb18968 (CD3-CD38) in relapsed or refractory acute myeloid leukemia and T-cell lymphoblastic leukemia/lymphoma has been t…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: CD7 CAR-T for Patients With r/r CD7+ T-ALL/T-LBL [EARLY_Phase 1]
A Phase 1 trial evaluating CD7-directed CAR-T therapy for relapsed/refractory CD7-positive T-cell acute lymphoblastic leukemia and T-lymphob…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Research Development（RD）13-02 Chimeric Antigen Receptor(CAR) -T Cell Injection for Patients With r/r Cluster Of Differentiation 7（CD7）+ T-Acute Lymphoblastic Leukemia(ALL)/T-Lymphoblastic Lymphoma(LBL) /Acute Myelogenous Leukemia(AML) [EARLY_Phase 1]
This early-phase (Phase 1) clinical trial update reports completion of a study evaluating CD7-targeted CAR-T cell therapy in patients with r…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: RD13-02 CAR-T Cell Injection for Patients With r/r CD7+ T-ALL/T-LBL [EARLY_Phase 1]
A Phase 1 trial evaluating RD13-02 CAR-T cell therapy for relapsed/refractory CD7-positive T-cell acute lymphoblastic leukemia and T-lymphob…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Phase I Clinical Trial of Autologous CD7-CAR T Cell Therapy for High-risk Acute T-cell Leukemia/lymphoma [Phase 1]
Phase I trial update for autologous CD7-CAR T cell therapy in high-risk acute T-cell leukemia/lymphoma; the study has completed.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Donor-Derived CD5 CAR T Cells in Subjects with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia [Phase 1]
This document notes the termination of a Phase 1 clinical trial evaluating donor-derived CD5 CAR T cells for relapsed or refractory T-cell a…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: MRD Detection by NGS in Pediatric T-ALL
This clinical trial update describes using next-generation sequencing to detect minimal residual disease in pediatric T-cell acute lymphobla…
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Treatment of Relapsed T-cell Acute Lymphoblastic Leukemia or T-lymphoblastic Lymphoma With MabCampath [Phase 2]
Phase 2 trial update investigating MabCampath for relapsed T-cell acute lymphoblastic leukemia or T-lymphoblastic lymphoma.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Modified TBF Regimen as Conditioning Regimen Prior to Allo-HSCT for T-ALL/LBL [Phase 2]
Phase 2 clinical trial evaluating a Modified TBF conditioning regimen before allogeneic stem cell transplant in T-ALL/LBL.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: 506U78 In Relapsed Or Refractory Acute Lymphoblastic Leukemia (T-ALL) [Phase 2]
Phase 2 clinical trial update for 506U78 in relapsed or refractory acute lymphoblastic leukemia (T-ALL) and T-NHL (lymphoblastic).
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating sapanisertib in adults with relapsed or refractory acute lymphoblastic leukemia; results were posted in Ma…
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CLINICAL_TRIALS trial_result · 2022-02-23Clinical Trial Update: Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma [Phase 3]
A Phase 3 clinical trial evaluating combination chemotherapy with or without bortezomib in younger patients with newly diagnosed T-cell acut…
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CLINICAL_TRIALS trial_result · 2022-02-23Clinical Trial Update: Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma [Phase 3]
A Phase 3 trial evaluating whether adding bortezomib to combination chemotherapy improves outcomes in younger patients with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2020-10-01Clinical Trial Update: Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL [Phase 1, Phase 2]
Phase 1/2 trial evaluating nelarabine combined with etoposide and cyclophosphamide in relapsed T-cell ALL and T-cell lymphoblastic lymphoma;…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of isatuximab in T-cell precursor acute leukemia/lymphoblastic lymphoma-leukemia was terminated with posted results.