Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating a BCMA/CD70-targeted CAR-T therapy for refractory pediatric rheumatic diseases is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance
This clinical trial update notes that a study sponsored by Hacettepe University is recruiting participants to evaluate chewing and swallowin…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL Questionnaire
The trial update outlines the cultural adaptation, validity, and reliability testing of the Turkish version of the PASTUL Questionnaire for …
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CLINICAL_TRIALS other · 2025-09-17Clinical Trial Update: Safety Study of CC312 in Autoimmune Disease Patients [EARLY_Phase 1]
Early-phase safety study of CC312 in multiple autoimmune diseases is currently recruiting, sponsored by CytoCares Inc.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Exploring the Patterns of Sleep Disordered Breathing in Systemic Sclerosis Patients
A clinical trial update describing a study to explore patterns of sleep-disordered breathing in patients with systemic sclerosis, which is n…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Assessment of GIT Vasculopathy in SSc and Its Multisystem Correlations
This clinical trial update describes an investigation of gastrointestinal vasculopathy in systemic sclerosis and its multisystem correlation…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating cyclophosphamide for systemic sclerosis-associated interstitia…
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CLINICAL_TRIALS other · 2025-09-12Clinical Trial Update: MPA AUC Monitoring in Patients Receiving MMF for Diffuse Cutaneous or Pulmonary Involvement in Systemic Sclerosis
The clinical trial evaluating monitoring of MPA AUC in MMF-treated systemic sclerosis patients with diffuse cutaneous or pulmonary involveme…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Personalized Home Respiratory Rehabilitation Program for Subjects With Systemic Sclerosis With Early Lung Disease [NA]
This clinical trial update indicates recruitment is open for a personalized home respiratory rehabilitation program for subjects with system…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Study of OL-CD19-GDT in Relapsed/ Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial evaluating OL-CD19-GDT for relapsed/refractory autoimmune diseases, including systemic sclerosis and Primary Sjögren'…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Chest CT Biomarkers as Prognostic Predictors in SSc-ILD
Sponsored by Royal Brompton & Harefield NHS Foundation Trust, this clinical trial investigates whether chest CT biomarkers can predict progn…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis [Phase 1, Phase 2]
This update indicates a Phase 1/2 clinical trial is recruiting to evaluate mesenchymal stromal cells for treating digital ulcers in systemic…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Evaluating the Effect of Questionnaire Context on the Reporting of Somatic Items Among People With Systemic Sclerosis [NA]
A completed clinical trial update investigating how questionnaire context influences reporting of somatic symptoms in systemic sclerosis; no…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: SPIN Self-Management Feasibility Trial With Progression to Full-scale Trial (SPIN-SELF) [NA]
Clinical trial update describing the SPIN Self-Management Feasibility Trial (SPIN-SELF) progressing to a full-scale study in systemic sclero…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: A Study of GB261 in Systemic Sclerosis [EARLY_Phase 1]
An early-phase 1 study evaluating GB261 for systemic sclerosis is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Intralesional Injection of STS in Treatment of Calcinosis [Phase 2]
A Phase 2 clinical trial evaluating intralesional sodium thiosulfate for calcinosis associated with systemic sclerosis and other connective …
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Study of Cizutamig in Systemic Sclerosis [EARLY_Phase 1]
This document reports an early phase 1 clinical trial evaluating Cizutamig in patients with Systemic sclerosis, with the study status listed…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases [NA]
An active but not recruiting clinical trial is testing UCAR T-cell therapy targeting CD19/BCMA in patients with systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre [NA]
Clinical trial update noting a cohort of patients with systemic sclerosis within the RESO Reference Centre; the study is currently recruitin…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy
This clinical trial update describes ongoing research in safety and efficacy assessment for rheumatologic diseases and related conditions, w…
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EMA approval · 2025-08-29EMA Authorised: Nintedanib Accord (nintedanib) — Accord Healthcare S.L.U.
The EMA authorised Nintedanib Accord for indications including Idiopathic Pulmonary Fibrosis, interstitial lung diseases, systemic sclerosis…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders [Phase 2]
This Phase 2 trial evaluating a COVID-19 booster vaccine in autoimmune-disease non-responders was terminated, with results posted on 2025-08…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study evaluating universal CD19-targeting CAR-γδT cells for refractory autoimmune diseases,…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: RENEW-AI: Personalizing Scleroderma Management With an AI Health Coach [NA]
This update reports the completion of the RENEW-AI trial evaluating an AI health coach to personalize management of systemic sclerosis (scle…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Metabolomic Analysis of Systemic Sclerosis
The ClinicalTrials.gov update reports that the metabolomic analysis study of systemic sclerosis and related connective tissue diseases has b…