Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Periodontal Microbiota in Systemic Sclerosis [NA]
A clinical trial registered at ClinicalTrials.gov is currently recruiting to study the relationship between periodontal microbiota and syste…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: A Study of MK-2225 in Healthy Participants (MK-2225-003) [Phase 1]
Phase 1 trial MK-2225-003 in healthy participants has completed, sponsored by Merck Sharp & Dohme LLC, with systemic sclerosis listed as the…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: DERMATOMICS: Identifying Regulators of Skin Homeostasis
This clinical trial update notes ongoing recruitment for a study called DERMATOMICS, exploring regulators of skin homeostasis in Systemic Sc…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases [Phase 1]
Phase 1 clinical trial of HBI0101 CAR-T therapy for refractory B-cell autoimmune diseases (SLE, systemic sclerosis, idiopathic inflammatory …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy [Phase 1]
Phase 1 clinical trial investigating C-CAR168 for autoimmune diseases refractory to standard therapy is currently recruiting, covering SLE, …
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Clinical trial update describing the EACVI study on multimodality cardiovascular imaging for inflammatory cardiovascular diseases, with myoc…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic Sclerosis [Phase 1]
A Phase 1 clinical trial update detailing the safety, tolerability, and pharmacokinetics assessment of RO7303509 in participants with system…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: GC012F in Patients With Autoimmune Diseases [EARLY_Phase 1]
This early-phase trial update reports on GC012F being studied for autoimmune diseases (systemic sclerosis and idiopathic inflammatory myopat…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: The Clinical Study on the Treatment of SSc With UTAA91 Injection. [EARLY_Phase 1]
A Phase 1 study evaluating UTAA91 injections for systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk [Phase 2, Phase 3]
This Clinical Trial Update notes a Phase 2/3 study evaluating whether clopidogrel can prevent the development of systemic sclerosis, with re…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial evaluating YTS109 cell therapy for relapsed/refractory autoimmune diseases is currently recruiting. The study cover…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: A Study of KHK4827 in Patients With Systemic Sclerosis [Phase 1]
The Phase 1 trial of KHK4827 in systemic sclerosis has completed. No results are provided in the summary.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis [Phase 3]
Phase 3 study of KHK4827 in moderate-to-severe systemic sclerosis has completed. The update does not include efficacy or safety results.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: TENS in Scleroderma [Phase 1]
A Phase 1 clinical trial update on using a TENS device for patients with systemic sclerosis (scleroderma) and associated gastroparesis, curr…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial investigating fecal microbiota transplantation to treat constipation and significant bloating in patients with system…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis [NA]
This clinical trial sponsored by The University of Texas Health Science Center, Houston is investigating the pathophysiological mechanisms o…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: PPI Refractory - GERD Mechanisms in Systemic Sclerosis
The trial investigates mechanisms of proton pump inhibitor-refractory gastroesophageal reflux disease in systemic sclerosis and is currently…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Clinical Study of Divozilimab in Patients With Systemic Scleroderma [Phase 3]
Biocad's Phase 3 clinical study of Divozilimab for systemic sclerosis is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Pathogenic Mechanisms Involved in the Initiation and Progression of Systemic Sclerosis [NA]
A clinical trial update examining pathogenic mechanisms involved in the initiation and progression of systemic sclerosis. It is currently no…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Color Doppler Ultrasonography Evaluation of Abdominal and Peripheral Vasculopathy in Systemic Sclerosis Patients
This clinical trial update describes a study using color Doppler ultrasonography to assess abdominal and peripheral vasculopathy in patients…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Occupational and Environmental Causes of Autoimmune Diseases [NA]
A clinical trial update indicates a study examining occupational and environmental factors in autoimmune diseases has completed. Conditions …
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Self-management Telehealth Program for Scleroderma [NA]
A completed clinical trial evaluating a self-management telehealth program for systemic sclerosis (scleroderma).
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2) [Phase 2]
This Phase 2 trial evaluated intravenous iloprost in subjects with Raynaud's phenomenon secondary to systemic sclerosis; results have been p…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection. [EARLY_Phase 1]
An early Phase 1 clinical trial is evaluating UTAA91 injection for Systemic sclerosis conducted by PersonGen BioTherapeutics (Suzhou) Co., L…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases [Phase 1]
A Phase 1 study evaluating OL-108 in relapsed/refractory autoimmune diseases is currently recruiting, including systemic lupus erythematosus…