Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial update on the recombinant herpes zoster vaccine in patients with autoimmune rheumatic diseases; the study is active b…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Scleroderma Registry & Repository at the Hospital for Special Surgery
Clinical trial registry update for a Scleroderma (systemic sclerosis) registry and repository at Hospital for Special Surgery; currently rec…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma [Phase 3]
Phase 3 trial evaluating topical cannabidiol lotion for pruritus relief in systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Rituximab in Systemic Sclerosis [Phase 2, Phase 3]
Rituximab is being evaluated for systemic sclerosis in Phase 2 and Phase 3 trials, and the study has completed.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety and Efficacy of Itacitinib in Adults With Systemic Sclerosis [Phase 2]
A Phase 2 clinical trial is investigating the safety and efficacy of itacitinib in adults with systemic sclerosis and is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Systemic Sclerosis' Relatives Reflex
The clinical trial investigating systemic sclerosis and caregiver-related outcomes has completed.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Multicenter Study on the Development of Pulmonary Arterial Hypertension Screening Models Based on Artificial Intelligence for Patients With Systemic Sclerosis
A multicenter clinical trial is investigating AI-based screening models for detecting pulmonary arterial hypertension in patients with syste…
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FDA approval · 2025-11-05FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
The FDA approved a supplemental application for Tracleer (bosentan) submitted by Actelion, resulting in an update to the product's labeling.
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FDA approval · 2025-11-05FDA Approved: BOSENTAN — Supplemental Application (Actavis Pharma, Inc.)
FDA approved a supplemental application for bosentan submitted by Actavis Pharma, Inc.
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease [Phase 1]
Synthekine reports a Phase 1 study of SYNCAR-001 plus STK-009 without lymphodepletion in subjects with severe, refractory systemic autoimmun…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating autologous stem cell transplantation in systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Sildenafil for Early Pulmonary Vascular Disease in Scleroderma [Phase 2]
A Phase 2 clinical trial evaluating sildenafil for early pulmonary vascular disease in patients with systemic sclerosis (scleroderma) is cur…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity [NA]
This document provides an update on a rheumatology-focused clinical trial sponsored by Brigham and Women's Hospital that studies an adaptive…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases [Phase 2]
Phase 2 autologous stem cell transplantation trial for autoimmune diseases is currently recruiting, including systemic lupus erythematosus a…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT [NA]
Pilot study imaging systemic sclerosis with CXCR4-targeted PET/CT to visualize inflammatory activity has completed.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis [Phase 1, Phase 2]
This document provides an update on KYSA-5, Kyverna Therapeutics' CD19 CAR T-cell trial for systemic sclerosis, indicating the study remains…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic Sclerosis
This clinical trial investigates catestatin as a biomarker for cardiovascular and microvascular involvement in systemic sclerosis.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. [EARLY_Phase 1]
Phase 1 study evaluating anti-CD19/BCMA universal CAR-T cell therapy RD06-05 in autoimmune diseases; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease [Phase 1, Phase 2]
Miltenyi Biomedicine is conducting Phase 1/2 trials of CAR-T cell therapy targeting B cells for autoimmune diseases, including systemic lupu…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis [NA]
A completed clinical trial comparing circulating epithelial and endothelial cells in primary Sjögren's syndrome and diffuse systemic scleros…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update assessing a dual CD19/BCMA-targeted CAR T-cell therapy for relapse/refractory autoimmune diseases, currently r…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Longitudinal Characterization of Microbial Signature in Systemic Sclerosis Patients
Clinical trial update noting ongoing recruitment for a study that longitudinally characterizes the microbial signature in systemic sclerosis…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Pulmonary Hypertension Screening in Scleroderma
A clinical trial update indicates a study screening for pulmonary hypertension in patients with systemic sclerosis (scleroderma) is not yet …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Mass Spectrometry-based Immune Profiling in Autoimmune Diseases
A clinical trial from Peking University People's Hospital evaluating mass spectrometry-based immune profiling across autoimmune diseases; th…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Patients Diagnosed With Scleroderma: Physical Performance and Functionality
Clinical trial update for NCT07183072 indicating ongoing recruitment at Hacettepe University to assess physical performance and functionalit…