Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Yoga Adjunct for Scleroderma [NA]
A completed clinical trial evaluating yoga as an adjunct therapy for systemic sclerosis (scleroderma).
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc) [Phase 2]
An open-label extension trial of HZNP-HZN-825-301 in adults with diffuse cutaneous systemic sclerosis was terminated; results have been post…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma. [Phase 2]
A Phase 2 clinical trial is evaluating subcutaneous injections of ASC to heal digital ulcers in systemic sclerosis. The study is currently r…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: 7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis [NA]
A clinical trial evaluated 7.0 Tesla MRI of the hand in systemic sclerosis. The study status is completed.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Analysis of Dermal Fibroblasts and Immune Cells During Systemic Sclerosis
This clinical trial from University Hospital, Lille is recruiting to analyze dermal fibroblasts and immune cells in patients with systemic s…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. [Phase 2]
Phase 2 trial evaluating AlloNK, an allogeneic cord blood-derived NK cell therapy, in combination with Rituximab for relapsing B-cell–depend…
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CLINICAL_TRIALS other · 2025-12-24Clinical Trial Update: Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating BCT301 cell injection therapy for refractory autoimmune diseases, including systemic lupus erythe…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Role of Eosinophil in Fibrogenesis of Systemic Sclerosis
A completed clinical trial investigating the role of eosinophils in the fibrogenesis of systemic sclerosis.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Prevalence of Hyperprolactinemia in Systemic Scleroderma
This completed clinical trial update from University Hospital, Lille evaluates how common hyperprolactinemia is in patients with systemic sc…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Description of the Functional Evolution of Diffuse Infiltrating Pneumonia Associated With Systemic Scleroderma.
A completed clinical trial update describes the functional evolution of diffuse infiltrating pneumonia in patients with systemic sclerosis.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis. [NA]
This document provides an update on a clinical trial investigating the profibrotic role of B lymphocytes in patients with systemic sclerosis…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Clinical Relevance of Thoracic Echography for the Early Diagnosis of Interstitial Lung Disease in Systemic Scleroderma - Pilot Study [NA]
A completed pilot study evaluating whether thoracic echography can aid early diagnosis of interstitial lung disease in systemic sclerosis. T…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Clinical Study of CD19 CAR-T in the Treatment of Refractory Systemic Sclerosis [Phase 1]
A Phase 1 clinical trial is studying CD19 CAR-T cell therapy for refractory systemic sclerosis (scleroderma). The study is currently recruit…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases [NA]
A clinical trial update evaluating CD19 UCAR-T cell therapy in autoimmune diseases; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Skin Fibrosis Analysis by Raman Spectroscopy in Systemic Sclerosis
The clinical trial evaluating Raman spectroscopy for assessing skin fibrosis in systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma [NA]
A clinical trial evaluating a biopsychosocial model-based exercise approach for children and adults diagnosed with scleroderma (systemic scl…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease [Phase 1]
A Phase 1 safety and efficacy study of CTX112 in adults with refractory autoimmune diseases, including systemic lupus erythematosus and syst…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE) [Phase 3]
This update outlines a Phase 3 clinical trial evaluating the long-term safety and efficacy of belimumab in adults with interstitial lung dis…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Study of MT-0551 in Patients With Systemic Sclerosis [Phase 3]
Phase 3 clinical trial update for MT-0551 in systemic sclerosis, currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1 [NA]
A trial (Trial #1) is evaluating tools to communicate scleroderma research results to patients, sponsored by the Lady Davis Institute. The s…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Evaluation of Calcinosis in Systemic Sclerosis
A clinical trial evaluating calcinosis in systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies
This clinical trial aims to characterize autoreactive B lymphocytes in autoimmune diseases and immune deficiencies. The study status is not …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis [NA]
A clinical trial is recruiting to evaluate diosmin for the treatment of digital ulcers in systemic sclerosis (scleroderma).
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients
A recruiting clinical trial examining interferon signature differences between cancer patients treated with anti-CTLA-4 or anti-PD-1/PD-L1 t…