Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-11-29Clinical Trial Update: Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis [NA]
Completed clinical trial evaluating ambrisentan in combination with an antifibrotic agent for diffuse systemic sclerosis; results posted in …
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Hands on - a Hand Care Guide in Systemic Sclerosis [NA]
A completed clinical trial update for a hand care guide in systemic sclerosis (scleroderma) with results posted in 2018.
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FDA approval · 2018-10-25FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
FDA approved a supplemental application for Tracleer (bosentan) submitted by Actelion Pharmaceuticals US, Inc.
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CLINICAL_TRIALS trial_result · 2018-09-10Clinical Trial Update: Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease [Phase 2]
Phase 2 clinical trial update for probiotics in systemic sclerosis-related gastrointestinal disease.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Mechanisms of Pulmonary Diffusion Limitation in Systemic Sclerosis
This completed clinical trial investigated mechanisms of diffusion limitation of pulmonary gas exchange in patients with systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: IVIG Treatment in Systemic Sclerosis [NA]
Clinical trial update on intravenous immunoglobulin (IVIG) treatment for systemic sclerosis, including the diffuse cutaneous form; the trial…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma [Phase 1]
A Phase 1 trial assessing the safety and suitability of dabigatran to inhibit thrombin in patients with scleroderma has completed. The study…
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis [Phase 1]
This clinical trial update reports on the prevalence and predictors of partial response to proton pump inhibitors in gastroesophageal reflux…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease [Phase 3]
A Phase 3 trial comparing mycophenolate mofetil for systemic sclerosis-related early interstitial lung disease has completed.
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis [Phase 1, Phase 2]
This document reports the completion of a Phase 1/2 trial evaluating allogeneic hematopoietic cell transplantation for severe systemic scler…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR) [NA]
A completed clinical trial evaluated Celution processed adipose-derived regenerative cells (STAR) for treating scleroderma (systemic scleros…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: IL1-TRAP, Rilonacept, in Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports on IL1-TRAP (rilonacept) for systemic sclerosis (scleroderma), with the study completed and result…
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CLINICAL_TRIALS research · 2018-05-01Clinical Trial Update: EBMT ADWP Prospective Non Interventional Study : AutoHSCT in SSc Patients
This document reports the completion of the EBMT ADWP prospective non-interventional study evaluating autologous hematopoietic stem cell tra…
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CLINICAL_TRIALS research · 2018-05-01Clinical Trial Update: Echo Systemic Sclerosis
An update on the Echo Systemic Sclerosis trial sponsored by University Hospital Clermont-Ferrand, listing systemic sclerosis and Sjögren's s…
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CLINICAL_TRIALS research · 2018-03-07Clinical Trial Update: Pulmonary Arterial Hypertension in Systemic Sclerosis
Update on a clinical trial examining pulmonary arterial hypertension in patients with systemic sclerosis (NCT00617487); current status is no…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Imatinib Mesylate (Gleevec) in the Treatment of Systemic Sclerosis [Phase 2]
Phase 2 clinical trial of imatinib mesylate (Gleevec) for systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: A Pilot-Study of Sirolimus for the Treatment of Systemic Sclerosis [Phase 2]
An update on a Phase 2 pilot study evaluating sirolimus as a treatment for systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis [NA]
A completed clinical trial evaluating neuropsychiatric involvement in systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Zibotentan Better Renal Scleroderma Outcome Study [Phase 2]
Phase 2 trial evaluating Zibotentan for renal outcomes in systemic sclerosis (scleroderma) has completed, with results summarized in this up…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Novel Rehabilitation Strategies to Improve Arm Function in Patients With Scleroderma [NA]
This completed clinical trial evaluated novel rehabilitation strategies to improve arm function in patients with systemic sclerosis (sclerod…
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FDA approval · 2017-10-20FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
FDA approved a supplemental application for Tracleer (bosentan) from Actelion Pharmaceuticals US, expanding its regulatory approval. The act…
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CLINICAL_TRIALS trial_result · 2017-10-04Clinical Trial Update: Nilotinib in the Treatment of Systemic Sclerosis [Phase 2]
Phase 2 clinical trial on nilotinib for systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-09-12Clinical Trial Update: A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis [Phase 4]
Phase 4 clinical trial update evaluating ambrisentan and tadalafil in pulmonary arterial hypertension associated with systemic sclerosis; st…
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CLINICAL_TRIALS research · 2017-08-30Clinical Trial Update: CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
The CLUE study on the etiology of leg ulcers in connective tissue disease patients has completed, with the document noting completion and no…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: The Effect of Ethanol Extract Physalis Angulata Linn. in Scleroderma Patients With Standard Therapy [NA]
Completed clinical study evaluating an ethanol extract of Physalis angulata in systemic sclerosis patients receiving standard therapy; no re…