Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2010-05-21Clinical Trial Update: Efferocytosis and Genomic Polymorphism in Autoimmune Diseases
This clinical trial update examines the relationship between efferocytosis and genomic polymorphisms in autoimmune diseases, including syste…
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CLINICAL_TRIALS trial_result · 2010-04-16Clinical Trial Update: FolateScan in Autoimmune Disease [Phase 2]
A Phase 2 clinical trial of FolateScan in autoimmune diseases has completed, including rheumatoid arthritis, osteoarthritis, multiple sclero…
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CLINICAL_TRIALS trial_result · 2010-03-24Clinical Trial Update: Statins and Lupus: Effects of Statins on Clinical Lupus Parameters, Serological Markers and Toll-like Receptors [Phase 1, Phase 2]
The study, a Phase 1/Phase 2 trial, evaluated the effects of statins on clinical lupus parameters, serological markers, and Toll-like recept…
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FDA approval · 2010-02-02FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for Mycophenolate mofetil submitted by Teva Pharmaceuticals USA, Inc.
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CLINICAL_TRIALS trial_result · 2009-12-18Clinical Trial Update: A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus [Phase 3]
Phase 3 study evaluating the safety of rituximab retreatment in systemic lupus erythematosus was terminated, with results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-12-15Clinical Trial Update: QT Dispersion in Patients With Systemic Lupus Erythematosus (SLE)
A completed clinical trial evaluating QT dispersion in patients with systemic lupus erythematosus (SLE) is reported.
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CLINICAL_TRIALS trial_result · 2009-12-02Clinical Trial Update: Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc) [Phase 1]
Phase 1 trial evaluating reduced-intensity transplant for medically refractory systemic lupus erythematosus and systemic sclerosis was termi…
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FDA approval · 2009-11-30FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for Accord Healthcare's generic mycophenolate mofetil. The product is used to prevent organ transpla…
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CLINICAL_TRIALS research · 2009-10-08Clinical Trial Update: Physical Activity in Patients With Systemic Lupus Erythematosus [Phase 1]
This document summarizes a Phase 1 clinical trial evaluating physical activity in patients with systemic lupus erythematosus, with the study…
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CLINICAL_TRIALS trial_result · 2009-10-05Clinical Trial Update: TNF Blockade With Remicade in Active Lupus Nephritis WHO Class V (TRIAL ) [Phase 2, Phase 3]
A Phase 2/3 trial evaluating infliximab (Remicade) for active lupus nephritis (WHO Class V) has been terminated.
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CLINICAL_TRIALS trial_result · 2009-09-23Clinical Trial Update: A Study of the Metabolic Syndrome in Patients With Systemic Lupus Erythematosus
This completed clinical trial studied metabolic syndrome in patients with systemic lupus erythematosus and evaluated related cardiovascular …
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CLINICAL_TRIALS trial_result · 2009-09-22Clinical Trial Update: Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular Studies [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of Faslodex (fulvestrant) for systemic lupus erythematosus has been completed.
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FDA approval · 2009-09-09FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for mycophenolate mofetil submitted by Hikma Pharmaceuticals USA Inc., updating the labeling for…
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CLINICAL_TRIALS trial_result · 2009-04-01Clinical Trial Update: Study of LJP 394 in Lupus Patients With History of Renal Disease [Phase 3]
A Phase 3 study of LJP 394 in patients with systemic lupus erythematosus and a history of renal disease has been terminated.
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CLINICAL_TRIALS research · 2009-03-20Clinical Trial Update: Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level [Phase 4]
Phase 4 trial comparing simvastatin and rosuvastatin in systemic lupus erythematosus patients on corticosteroids with high LDL cholesterol, …
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CLINICAL_TRIALS research · 2009-03-05Clinical Trial Update: Cyclophosphamide in Lupus Nephritis
An update on a clinical trial evaluating cyclophosphamide for lupus nephritis in systemic lupus erythematosus, sponsored by the University o…
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CLINICAL_TRIALS trial_result · 2009-01-28Clinical Trial Update: Memory and Attention Problems in Lupus: New Treatment Trial With Modafinil [NA]
A clinical trial evaluating modafinil for memory and attention problems in systemic lupus erythematosus was terminated.
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CLINICAL_TRIALS research · 2008-12-31Clinical Trial Update: The Systemic Lupus Erythematosus (SLE) Activity Gene Expression (SAGE) Study
This document provides an update on the Systemic Lupus Erythematosus Activity Gene Expression (SAGE) study, a clinical investigation examini…
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CLINICAL_TRIALS trial_result · 2008-11-06Clinical Trial Update: High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide [Phase 3]
Phase 3 trial comparing high-dose intravenous cyclophosphamide with monthly IV cyclophosphamide in systemic lupus erythematosus has complete…
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CLINICAL_TRIALS research · 2008-09-08Clinical Trial Update: Health-Related Quality of Life and Disease-Related Costs: Comparison Between Ankylosing Spondylitis, Rheumatoid Arthritis and Systemic Lupus Erythematosus in Taiwan
Clinical trial comparing health-related quality of life and disease-related costs among ankylosing spondylitis, rheumatoid arthritis, and sy…
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CLINICAL_TRIALS trial_result · 2008-06-17Clinical Trial Update: Mesenchymal Stem Cells Transplantation for Refractory Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
Phase 1/2 clinical trial update examining mesenchymal stem cell transplantation for refractory systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2008-05-23Clinical Trial Update: Study to Evaluate the Safety, Tolerability and Short Term Efficacy of Extracorporeal Specific Immunoadsorption LupusorbTM Columns for the Treatment of Systemic Lupus Erythematosus (SLE) Patients [NA]
This clinical trial evaluates the safety, tolerability and short-term efficacy of Lupusorb Columns for treatment of systemic lupus erythemat…
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CLINICAL_TRIALS withdrawal · 2008-05-08Clinical Trial Update: Study of TRU-015 in Subjects With Membranous Nephropathy Secondary to Systemic Lupus Erythematosus [Phase 1]
Phase 1 study of TRU-015 for membranous nephropathy secondary to systemic lupus erythematosus was terminated.
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CLINICAL_TRIALS trial_result · 2008-04-09Clinical Trial Update: Drug Therapy in Lupus Nephropathy [Phase 2]
Phase 2 clinical trial evaluating a drug therapy for lupus nephropathy in nephrotic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2008-03-28Clinical Trial Update: Leflunomide in Systemic Lupus Erythematosus [Phase 2]
A Phase 2 trial of Leflunomide for systemic lupus erythematosus (SLE) sponsored by Sanofi has completed.