Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: The Purpose of This Study is to Evaluate the Efficacy and Safety of 626 in the Treatment of SLE [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the efficacy and safety of a drug named 626 for systemic lupus erythematosus. The study is currentl…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: miR-101-3p and Autotaxin in SLE Patients
This document reports a clinical study evaluating the roles of miR-101-3p and autotaxin in patients with Systemic Lupus Erythematosus, with …
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: MB-CART19.1 in Refractory SLE [Phase 1, Phase 2]
Miltenyi Biomedicine's MB-CART19.1 is being studied in Phase 1/2 trials for refractory systemic lupus erythematosus, with recruitment ongoin…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) [Phase 1]
Phase 1 clinical trial update for SC291 in severe B-cell–mediated autoimmune diseases; the study is active but not recruiting and includes s…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF [Phase 3]
Phase 3 trial update comparing induction therapy for lupus nephritis with oral corticosteroids plus mycophenolate mofetil (MMF) versus obinu…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Safety, Efficacy and Cellular Metabolic Dynamics of ct1192 in Patients With Moderate to Severe Refractory SLE [Phase 1]
A Phase 1 clinical trial investigating the safety, efficacy, and cellular metabolic dynamics of ct1192 in adults with moderate to severe ref…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety and Efficacy of ONT01 in Lupus [EARLY_Phase 1]
ONT01 is in an early Phase 1 trial for lupus nephritis and systemic lupus erythematosus and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)
A completed clinical trial registry entry for patients with antiphospholipid syndrome and/or systemic lupus erythematosus, sponsored by Assi…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Probiotics in Systemic Lupus Erythematosus [Phase 2]
Phase 2 trial investigating probiotics for systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE [Phase 1]
A Phase 1 clinical trial is evaluating an Ultra-Fast CD19 CAR-T cell therapy for refractory systemic lupus erythematosus; the study is curre…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Clinical Study of Cizutamig in Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial of Cizutamig for systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus [Phase 1]
Phase 1 study of belimumab in Chinese pediatric participants with systemic lupus erythematosus has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Breaking Implicit Bias Habits: An Individuation Pilot Study In Rheumatology [NA]
A completed rheumatology pilot trial evaluating an intervention to break implicit bias habits through individuation, with results posted.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: 2-HOBA in Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial of 2-HOBA for systemic lupus erythematosus is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
A clinical trial is evaluating an educational tool to help melanoma patients with pre-existing autoimmune diseases who are candidates for im…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease [Phase 1]
Synthekine reports a Phase 1 study of SYNCAR-001 plus STK-009 without lymphodepletion in subjects with severe, refractory systemic autoimmun…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus [NA]
This clinical trial is currently recruiting participants for a study on childhood-onset systemic lupus erythematosus led by Michigan State U…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Quantum-Synaptic Immunotherapy Mapping Using Low-Frequency Electromagnetic Resonance and Machine Learning-Based Cytokine Forecasting [Phase 1, Phase 2]
This Phase 1/2 clinical trial update describes enrollment for a Quantum-Synaptic Immunotherapy approach that uses low-frequency electromagne…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Anifrolumab Asian PhIII Efficacy Study for Systemic Lupus Erythematosus (SLE) [Phase 3]
This update reports the completion of a Phase 3 Asian efficacy study of anifrolumab for active systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity [NA]
This document provides an update on a rheumatology-focused clinical trial sponsored by Brigham and Women's Hospital that studies an adaptive…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases [Phase 2]
Phase 2 autologous stem cell transplantation trial for autoimmune diseases is currently recruiting, including systemic lupus erythematosus a…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Implementing the Decision-Aid for Lupus (IDEAL Strategy)
This clinical trial update reports results from the IDEAL Strategy decision-aid study for systemic lupus erythematosus; the study is complet…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Real World Evidence of Anifrolumab in Systemic Lupus Erythematosus: Investigator Initiated, Observational, Multicenter Study Evaluating Effectiveness and Safety of Anifrolumab in Active SLE Patients
Investigator-initiated, observational multicenter real-world study evaluating the effectiveness and safety of Anifrolumab in active systemic…
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EMA approval · 2025-10-07EMA Authorised: Benlysta (belimumab) — GlaxoSmithKline Trading Services Limited
The European Medicines Agency authorised Benlysta (belimumab) for systemic lupus erythematosus in the European Union.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: European LUpuS Inception-Cohort Developing initiATivE
This clinical trial update describes a European inception-cohort study for systemic lupus erythematosus led by the University of Aarhus, whi…