Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Study of VIB7734 for the Treatment of Moderate to Severely Active SLE [Phase 2]
Phase 2 study of VIB7734 in moderate-to-severe systemic lupus erythematosus has completed, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy. [Phase 2]
A multicenter Phase 2 trial evaluating the immunogenicity of HPV vaccination in girls on immunosuppressive therapy, including those with sys…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Neuromuscular Ultrasonography Assessment of Optic Nerve in Systemic Lupus Eryhematosus
Completed clinical study evaluating neuromuscular ultrasonography of the optic nerve in patients with optic neuropathy associated with syste…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus [Phase 2]
A Phase 2 trial evaluating Efavaleukin Alfa for active systemic lupus erythematosus was terminated, with efficacy and safety results posted …
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE [NA]
A terminated UNC-Chapel Hill study assessed transcranial alternating current stimulation to address depression, cognitive deficits, and pain…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Neutrophil Extracellular Traps in Systemic Sclerosis [NA]
A completed clinical study investigating neutrophil extracellular traps in patients with systemic sclerosis and systemic lupus erythematosus…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Prospective Study of Rapamycin for the Treatment of SLE [Phase 2]
A Phase 2 prospective trial evaluating rapamycin for systemic lupus erythematosus has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Transcriptional and Immune Parameters of Response to Belimumab
This completed study analyzes transcriptional and immune parameters associated with response to belimumab in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Study the Efficacy and Safety of VAY736 and CFZ533 in SLE Patients [Phase 2]
Phase 2 trial assessing the efficacy and safety of VAY736 and CFZ533 in systemic lupus erythematosus has completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Phase 1b/2a Study to Evaluate Safety and Efficacy of KPG-818 in SLE [Phase 1, Phase 2]
Phase 1b/2a study evaluating safety and efficacy of KPG-818 in systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Stress, Inflammation and Immune Response Pilot Study- Aim 3 [EARLY_Phase 1]
This early-phase Phase 1 pilot trial investigates how stress, inflammation, and immune response interact in systemic lupus erythematosus, an…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity [NA]
A clinical trial update notes that enrollment is ongoing by invitation for a study evaluating methyl-donor nutrient supplementation and meth…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE) [Phase 2]
Phase 2 trial of LY3471851 in adults with systemic lupus erythematosus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus [Phase 3]
Phase 3 clinical trial investigating telitacicept plus low-dose IL-2 for efficacy and immunological effects in systemic lupus erythematosus,…
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE) [Phase 1]
Phase 1 trial evaluating TAK-079 in combination with standard therapy in moderate to severe systemic lupus erythematosus; study completed wi…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE) [Phase 2]
Phase 2 study evaluating subcutaneous belimumab in pediatric patients with systemic lupus erythematosus. The study results were posted on 20…
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis [Phase 1, Phase 2]
Kezar Life Sciences completed a Phase 1/2 study of the immunoproteasome inhibitor KZR-616 in systemic lupus erythematosus with and without l…
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Trial of Belimumab in Early Lupus [Phase 4]
Phase 4 trial updating on belimumab in early systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Anti-CD20 Antibodies for Treatment of SLE-PAH [Phase 4]
Phase 4 clinical trial update evaluating anti-CD20 antibodies for treatment of systemic lupus erythematosus-associated pulmonary arterial hy…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE Patients [Phase 4]
Phase 4 clinical trial exploring multi-omics studies on the efficacy of telitacicept in Chinese patients with systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis [Phase 2]
Phase 2 trial assessing Branebrutinib in active autoimmune diseases (systemic lupus erythematosus, primary Sjögren's syndrome) and rheumatoi…
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: RIvaroxaban for Stroke Patients With AntiPhospholipid Syndrome [Phase 2]
Phase 2 clinical trial update for rivaroxaban in stroke patients with antiphospholipid syndrome and related autoimmune conditions.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Immune Ablation and Hematopoietic Stem Cell Support in Patients With Systemic Lupus Erythematosus: A Phase II Study [Phase 2]
A Phase II trial evaluating immune ablation with hematopoietic stem cell support in patients with systemic lupus erythematosus has completed…
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis [Phase 1]
Phase 1 safety and tolerability trial of PF-06835375 in seropositive systemic lupus erythematosus and rheumatoid arthritis completed; result…
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Safety and Efficacy of SM934 Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus [Phase 2]
Phase 2 trial assessing safety and efficacy of SM934 versus placebo in adults with active systemic lupus erythematosus has completed.