Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE) [Phase 1]
A Phase 1 clinical trial is evaluating autologous CD19 CAR T-cell therapy for severe refractory systemic lupus erythematosus, and the study …
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial is evaluating anti-CD19 CAR-NK cells in patients with refractory/relapsed systemic lupus erythematosus. The study i…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: Transcutaneous Vagus Nerve Stimulation in SLE [Phase 2]
A Phase 2 clinical trial investigating transcutaneous vagus nerve stimulation for systemic lupus erythematosus is not yet recruiting, sponso…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Efficacy and Safety of Belimumab in SLE Patients [Phase 4]
A Phase 4 trial evaluating the efficacy and safety of belimumab in systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical study evaluating YTS109 cells in relapsed/refractory systemic lupus erythematosus, including lupus nephritis and immune t…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)
Trial update reporting the termination of a Johns Hopkins University study evaluating kidney MRI in patients with systemic lupus erythematos…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered Mosunetuzumab to Participants With Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial evaluating subcutaneously administered mosunetuzumab in systemic lupus erythematosus has completed its assessment o…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus [Phase 3]
Phase 3 trial update reporting efficacy and safety results for Dapirolizumab Pegol in moderately to severely active Systemic Lupus Erythemat…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Hematological Manifestations in Systemic Lupus Erythematosus Patients
This clinical trial update reports on hematological manifestations in patients with Systemic Lupus Erythematosus and notes that the study ha…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis [Phase 1]
Phase 1 study of EQ001 (Itolizumab) in systemic lupus erythematosus with or without active proliferative nephritis has completed and posted …
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of Single Doses of HC022 in Healthy Subjects. [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of single doses of HC022 in healthy subjects, with systemic lupus er…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients [Phase 4]
Phase 4 trial update assessing cardio-renal effects of SGLT2 inhibitors in lupus nephritis patients; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: A Study of DS-7011a in Patients With Systemic Lupus Erythematosus [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating DS-7011a in patients with systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases [Phase 2]
Phase 2 clinical trial update on BCMA-CD19 CAR-T therapy for refractory autoimmune diseases, currently recruiting. The study targets several…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Improving the Assessment of SLE Disease Activity
A completed clinical trial update describing efforts to improve the assessment of disease activity in systemic lupus erythematosus (SLE).
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Myofascial Techniques and Proprioceptive Neuromuscular Facilitation in Patients With Systemic Lupus Erythematosus. [NA]
This clinical trial update reports on a completed study evaluating myofascial techniques and proprioceptive neuromuscular facilitation in pa…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Observational Multicenter Case-control Study to Assess Nailfold Capillary Abnormalities in Systemic Lupus Erythematosus
A completed multicenter observational case-control study investigating nailfold capillary abnormalities in patients with Systemic Lupus Eryt…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: The Prevalence Evaluation of Systemic Lupus Erythematosus in Russian Patients With Reproductive Issues (PRISMA)
This entry notes the completion of AstraZeneca's PRISMA trial evaluating the prevalence of systemic lupus erythematosus in Russian patients …
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers [Phase 1]
Phase I study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of subcutaneously administered CUG252 in healthy volunt…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus [NA]
A completed clinical trial evaluated telehealth cognitive behavioral therapy for adolescents and young adults with childhood-onset systemic …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Study of Imvotamab in Severe Systemic Lupus Erythematosus [Phase 1]
A Phase 1 study of Imvotamab for severe systemic lupus erythematosus has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Single Ascending Dose Study in Healthy Participants and Multiple Dose Study of JNJ-55920839 in Participants With Mild to Moderate Systemic Lupus Erythematosus [Phase 1]
This document reports the completion of a Phase 1 single ascending dose study in healthy participants and a multiple-dose study of JNJ-55920…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Addressing Disparities in Lupus Care Through an Integrated Care Management Program [NA]
Completed clinical trial from Brigham and Women's Hospital evaluating an integrated care management program to address disparities in System…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus [Phase 2]
A Phase 2 IMMA Master Protocol trial of LY3361237 in participants with at least moderately active systemic lupus erythematosus was terminate…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State [Phase 2]
Phase 2 safety study evaluating elsubrutinib, upadacitinib, or their combination (ABBV-599) in adults with moderately to severely active sys…