Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: BENLYSTA® Special Drug Use Investigation
This entry notes the completion of GlaxoSmithKline's Special Drug Use Investigation for BENLYSTA (belimumab) in systemic lupus erythematosus…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
CRC01 is being evaluated in a Phase 1/2 clinical trial for severe refractory systemic lupus erythematosus, including lupus nephritis, with t…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study to Assess Demographic, Pharmacologic, Biomarker, Clinical Features and Quality of Life (QoL) of Participants With Lupus Nephritis
A completed study by GlaxoSmithKline examining demographic, pharmacologic, biomarker, clinical features, and quality of life in participants…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating the safety and efficacy of a targeted BCMA in vivo lentiviral vector injection for recurrent or r…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1) [Phase 1]
Phase 1 Breakfree-1 trial evaluating CC-97540, a CD-19-targeted Nex-T CAR T cell therapy, for severe, refractory autoimmune diseases; the st…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1) [Phase 3]
A Phase 3 study (REMESLE-1) evaluating telitacicept for moderately to severely active systemic lupus erythematosus has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: BCMA-CD19 cCAR T for the Treatment of Refractory Lupus [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BCMA-CD19 cCAR T therapy for refractory systemic lupus erythematosus and lupus nephritis, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Description of Compliance With Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus
A completed clinical trial update describes how well patients with systemic lupus erythematosus adhered to hydroxychloroquine therapy.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Immune Response to SARS-CoV-2 Vaccination in Systemic Lupus
The clinical trial studying the immune response to SARS-CoV-2 vaccination in patients with Systemic lupus erythematosus has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Abnormalities of B Lymphocytes During Systemic Lupus [NA]
A completed clinical trial at University Hospital Strasbourg studying abnormalities of B lymphocytes in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: GENetic & Immunologic Abnomalies in Systemic Lupus Erythematosus [NA]
A completed clinical trial from Hospices Civils de Lyon studied genetic and immunologic abnormalities in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE Participants [Phase 1, Phase 2]
This update reports a Phase 1/2a clinical trial of DB-2304 in healthy adults and participants with Systemic Lupus Erythematosus, which is cu…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease [Phase 1]
A Phase 1 safety and efficacy study of CTX112 in adults with refractory autoimmune diseases, including systemic lupus erythematosus and syst…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study [Phase 2]
Phase 2 study of EG-501 in cognitive impairment associated with neuropsychiatric lupus has completed, evaluating efficacy and safety.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Subcutaneous Injections of SHR-2173 in Patients With Systemic Lupus Erythematosus [Phase 1]
Phase I clinical study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple subcutaneous injections of SHR-21…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Study of Nipocalimab in Adult Participants With Active Systemic Lupus Erythematosus [Phase 2]
A Phase 2 study evaluating Nipocalimab in adults with active systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: CD19/BCMA CAR-T for SLE [EARLY_Phase 1]
An early-phase 1 clinical trial evaluates a CD19/BCMA CAR-T therapy for systemic lupus erythematosus (SLE). The study is currently not yet r…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial update on the recombinant herpes zoster vaccine in patients with autoimmune rheumatic diseases; the study is active b…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Water-based Liuzijue Exercise on Childhood-onset Systemic Lupus Erythematosus [NA]
A completed clinical trial evaluating the effects of water-based Liuzijue exercise on childhood-onset systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW) [Phase 2]
The WILLOW Phase 2 study evaluated M5049 in systemic lupus erythematosus with cutaneous lupus erythematosus (SCLE/DLE) and has completed wit…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Vagus Nerve Stimulation for Fatigue in Systemic Lupus [NA]
A completed clinical trial evaluated vagus nerve stimulation as a treatment for fatigue in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) [Phase 4]
A Phase 4 clinical trial is evaluating the efficacy and safety of belimumab in adult participants with early systemic lupus erythematosus an…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Probiotics in Systemic Lupus Erythematosus [Phase 2]
Phase 2 trial investigating probiotics for systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE [Phase 1]
A Phase 1 clinical trial is evaluating an Ultra-Fast CD19 CAR-T cell therapy for refractory systemic lupus erythematosus; the study is curre…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Clinical Study of Cizutamig in Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial of Cizutamig for systemic lupus erythematosus is currently recruiting.