Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Study to Compare Properties of Epratuzumab When Given as an Injection Under the Skin or Directly Into the Blood [Phase 1]
Phase 1 study comparing subcutaneous versus intravenous administration of epratuzumab in systemic lupus erythematosus has been completed.
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Low-dose IL-2( Interleukin-2) Treatment in SLE [NA]
A completed clinical trial evaluating low-dose interleukin-2 therapy for systemic lupus erythematosus; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 623 in Subjects With Systemic Lupus Erythematosus [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics and pharmacodynamics of AMG 623 in subjects with systemic lupus erythematosus has be…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics and pharmacodynamics of AMG 557 in systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders [Phase 1]
Completed Phase 1 pilot study evaluating total body irradiation with cyclophosphamide, anti-thymocyte globulin, and autologous CD34-selected…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus Erythematosus [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of AMG 811 in Systemic Lupus Erythematosus has complet…
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Biomarkers of Lupus Disease: Serial Biomarker Sampling in Patients With Active Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
A completed Phase 1/2 study investigating serial biomarker sampling in patients with active systemic lupus erythematosus to identify disease…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: Abatacept and Cyclophosphamide Combination Therapy for Lupus Nephritis [Phase 2]
Phase 2 clinical trial evaluating the combination of abatacept and cyclophosphamide for lupus nephritis completed with results posted in 201…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Effect of Pioglitazone on Endothelial Function in Premenopausal Women With Uncomplicated Systemic Lupus Erythematosus [Phase 4]
Phase 4 trial studying the effect of pioglitazone on endothelial function in premenopausal women with uncomplicated systemic lupus erythemat…
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus [Phase 1]
Amgen conducted a Phase 1 safety study of AMG 811 in subjects with discoid lupus erythematosus, which has been terminated.
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Safety Study of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without Glomerulonephritis [Phase 1]
Amgen's Phase 1 safety study of AMG 811 in subjects with systemic lupus erythematosus, with and without lupus nephritis, has completed.
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: A Non-drug Study Profiling Cutaneous Lupus
A completed non-drug clinical trial profiling cutaneous lupus and related lupus forms including cutaneous, systemic, and discoid lupus eryth…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: A Prospective Study of Cyclophosphamide in Systemic Lupus Erythematosus Treatment [NA]
A completed prospective clinical trial evaluated the use of cyclophosphamide in systemic lupus erythematosus with results posted.
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CLINICAL_TRIALS trial_result · 2014-08-26Clinical Trial Update: A Safety and Tolerability Study of MEDI-570 in Systemic Lupus Erythematosus [Phase 1]
A Phase 1 safety and tolerability study of MEDI-570 in systemic lupus erythematosus was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-06-10Clinical Trial Update: Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus [Phase 2]
Phase 2 trial evaluating lymphocyte depletion and stem cell transplantation for severe systemic lupus erythematosus has completed with resul…
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion [Phase 3]
Phase 3 trial evaluating hydroxychloroquine sulfate for efficacy and safety in patients with systemic lupus erythematosus or cutaneous lupus…
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CLINICAL_TRIALS trial_result · 2014-04-25Clinical Trial Update: Vitamin D3 in Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial results explore the effects of vitamin D3 (cholecalciferol) in patients with systemic lupus erythematosus (SLE).
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CLINICAL_TRIALS trial_result · 2014-04-08Clinical Trial Update: An Investigation of Safety and Tolerability of NNC0114-0006 in Subjects With Systemic Lupus Erythematosus (SLE) [Phase 1]
Phase 1 trial evaluating the safety and tolerability of NNC0114-0006 in systemic lupus erythematosus. The study has been terminated.
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: PEARL-SC Trial: A Study of the Efficacy, Safety, and Tolerability of A 623 Administration in Subjects With Systemic Lupus Erythematosus [Phase 2]
This update notes the completion of enrollment for the Phase 2 PEARL-SC trial evaluating A-623 in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2014-02-13Clinical Trial Update: A Trial for Subjects With Systemic Lupus Erythematosus Who Have Completed Protocol AN-SLE3321 [Phase 2]
Anthera Pharmaceuticals completed the Phase 2 AN-SLE3321 trial in subjects with systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: Study Evaluating the Pharmacokinetics and Safety of Epratuzumab in Japanese Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
This update summarizes a Phase 1/2 study evaluating the pharmacokinetics and safety of epratuzumab in Japanese patients with systemic lupus …
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus [Phase 1]
A Phase 1 safety study of AMG 557 in subjects with subacute cutaneous lupus erythematosus was terminated.
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Effectiveness Study of Psychotherapy in Systemic Lupus Erythematosus [NA]
This clinical trial update describes an effectiveness study evaluating psychotherapy for systemic lupus erythematosus, sponsored by the Fede…
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CLINICAL_TRIALS trial_result · 2013-12-27Clinical Trial Update: Pilot Study - Effect of Omega-3 on Systemic Lupus Erythematosus [Phase 2]
Completed Phase 2 pilot clinical trial assessing the effect of omega-3 fatty acids on systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2013-12-24Clinical Trial Update: Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE) [Phase 2]
A Phase 2 clinical trial evaluating prevention of atherosclerosis and heart disease in patients with systemic lupus erythematosus has comple…