Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Double-Blinded, Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Biochemical Activity of Intravenous Cpn10 Administration in Subjects With Mild to Moderate SLE. [Phase 1, Phase 2]
Phase 1/2 trial evaluating intravenous Cpn10 in mild-to-moderate systemic lupus erythematosus; safety, tolerability, pharmacokinetics, and b…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: Safety Study of AMG 557 in Subjects With Lupus Arthritis [Phase 1]
Phase 1 safety data for AMG 557 in subjects with lupus arthritis and systemic lupus erythematosus has completed enrollment, and the update s…
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud [EARLY_Phase 1]
The document notes completion of an early Phase 1 trial comparing topical 10% nifedipine with 5% sildenafil for secondary Raynaud's phenomen…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Treating Systemic Lupus Erythematosus (SLE) Patients With CTLA4-IgG4m (RG2077) [Phase 1, Phase 2]
This document reports the completion of Phase 1/Phase 2 clinical trials evaluating CTLA4-IgG4m (RG2077) in patients with systemic lupus eryt…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
A completed study evaluating skin and systemic biomarkers in patients with active cutaneous lupus erythematosus and in healthy volunteers, s…
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: GSK1550188 A 52 Week Study of Belimumab Versus Placebo in the Treatment of Subjects With Systemic Lupus Erythematosus (SLE) Located in Northeast Asia [Phase 3]
A Phase 3 trial comparing belimumab to placebo over 52 weeks in systemic lupus erythematosus completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Efficacy of Fish Oil in Lupus Patients [Phase 4]
A Phase 4 trial assessed the efficacy of fish oil (omega-3 fatty acids) in patients with systemic lupus erythematosus, with results posted i…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Long-term Immunogenicity of a HPV Vaccine in SLE
The study reports long-term immunogenicity data for a human papillomavirus vaccine in patients with systemic lupus erythematosus (SLE).
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Enteric-coated Mycophenolate Sodium Versus Azathioprine for the Extra-renal Lupus Manifestations [Phase 4]
Phase 4 clinical trial comparing enteric-coated mycophenolate sodium with azathioprine for extra-renal manifestations of systemic lupus eryt…
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Comparison of the Clinical Examination and the Joint Ultrasonography in Lupus Patients [NA]
This clinical trial compared clinical examination and joint ultrasonography in patients with systemic lupus erythematosus to evaluate diagno…
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Catalytic Antibodies and Lupus in Martinique
This entry reports the completed clinical trial from Martinique examining catalytic antibodies in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Effect of Green Tea on Treatment of Lupus [Phase 2]
This Phase 2 trial evaluating the effect of green tea on the treatment of systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis [Phase 2]
This update reports the Phase 2 long-term safety results for MEDI-545 in adults with Systemic Lupus Erythematosus or Myositis. The study has…
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of MEDI-546 in Systemic Lupus Erythematosus was completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Systemic Lupus Erythematosus [Phase 2]
Phase 2 study of rontalizumab in adults with moderately to severely active systemic lupus erythematosus has completed, focusing on efficacy …
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Evaluation of the Discontinuation of Maintenance Corticosteroid Treatment in Quiescent Systemic Lupus [Phase 3]
Phase 3 clinical study evaluating whether maintenance corticosteroid treatment can be discontinued in patients with quiescent systemic lupus…
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: A Study to Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus [Phase 2]
Phase 2 clinical trial evaluating the safety and tolerability of subcutaneous MEDI-545 in subjects with systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2016-07-25Clinical Trial Update: A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE) [Phase 4]
Phase 4 trial evaluating belimumab's effect on vaccine responses in systemic lupus erythematosus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus [Phase 2]
The Phase 2 trial evaluating sifalimumab in adults with systemic lupus erythematosus has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2016-06-24Clinical Trial Update: Effectiveness of Pharmaceutical Care in the Adherence of Systemic Lupus Erythematosus Treatment [NA]
This completed clinical trial assesses whether pharmaceutical care improves adherence to treatment in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases [Phase 1]
Phase 1 trial update on nonmyeloablative allogeneic stem cell transplantation for systemic lupus erythematosus and systemic sclerosis, with …
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions [Phase 2]
Phase 2 trial evaluating the safety and efficacy of Topical R333 in patients with discoid lupus erythematosus and systemic lupus erythematos…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention [Phase 2, Phase 3]
Trial update notes that Dehydroepiandrosterone (DHEA) was studied in systemic lupus erythematosus patients to prevent coronary artery diseas…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Cholecalciferol Supplementation on Disease Activity, Fatigue and Bone Mass on Juvenile Systemic Lupus Erythematosus. [NA]
A completed juvenile SLE trial evaluated whether cholecalciferol (vitamin D3) supplementation affects disease activity, fatigue, and bone ma…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Rhupus Syndrome and Efficacy of Etanercept Treatment
A completed clinical trial evaluated the efficacy of etanercept in rhupus syndrome, an overlap of rheumatoid arthritis and systemic lupus er…