Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: GADD34 and Type I IFN Response Genes in SLE
A completed clinical trial conducted by University Hospital, Grenoble, examining the role of GADD34 and Type I interferon response genes in …
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Cyclophosphamide Versus Mycophenolate Mofetil in Lupus Nephritis [Phase 2]
A Phase 2 randomized trial comparing cyclophosphamide to mycophenolate mofetil in lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases [Phase 3]
Phase 3 trial evaluating GnRH agonist for ovarian protection during cyclophosphamide therapy in rheumatic diseases was terminated; results w…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Exploratory Study of MT-1303 in Systemic Lupus Erythematosus Patients [Phase 1]
An exploratory Phase 1 trial of MT-1303 in adults with systemic lupus erythematosus has been completed. The study was sponsored by Tanabe Ph…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Japanese phase1 Study of Belimumab (IV vs SC) [Phase 1]
A Japanese Phase 1 study comparing intravenous and subcutaneous belimumab in systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Phase I Study of GSK1550188 in Japanese Subjects With Systemic Lupus Erythematosus (SLE) [Phase 1]
This update reports the completion of a Phase I study of the investigational drug GSK1550188 in Japanese subjects with systemic lupus erythe…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Regulatory BCells in Systemic Lupus Erythematosus
A clinical trial update focusing on regulatory B cells in systemic lupus erythematosus; the current trial status is unknown.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: A Phase 2B Open-Label, Single-Arm, Repeat-Dose Study to Evaluate the Reliability of an Autoinjector [Phase 2]
Phase 2B open-label, single-arm study evaluating the reliability of an autoinjector for delivering a treatment for systemic lupus erythemato…
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: CHABLIS7.5: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis [Phase 3]
Phase 3 CHABLIS7.5 trial evaluating subcutaneous blisibimod for systemic lupus erythematosus with or without nephritis has been terminated.
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Effect Of Curcuma Xanthorrhiza and Vitamin D3 Supplementation in SLE Patients With Hypovitamin D [NA]
A completed clinical trial evaluating Curcuma Xanthorrhiza and Vitamin D3 supplementation in patients with systemic lupus erythematosus and …
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: A Study to Estimate the Relative Bioavailability, Tolerability and Safety of a Single Dose of Belimumab Self-Administered Subcutaneously (SC) by Healthy Subjects [Phase 1]
Phase 1 study evaluating self-administered subcutaneous belimumab in healthy subjects to estimate relative bioavailability, tolerability, an…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Pilot Study to Assess Flares Following Inactivated Influenza Vaccine in Children With Systemic Lupus Erythematosus (SLE)
Pilot study evaluating whether the inactivated influenza vaccine triggers disease flares in children with systemic lupus erythematosus. The …
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: A Continuation Trial for Subjects With Systemic Lupus Erythematosus That Have Completed Protocol LBSL02 [Phase 2]
A Phase 2 continuation trial for subjects with systemic lupus erythematosus who completed a prior protocol (LBSL02) has completed, with resu…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: An Adaptive Phase II Study to Evaluate the Efficacy, Pharmacodynamics, Safety and Tolerability of GSK2586184 [Phase 2]
Adaptive Phase II study of GSK2586184 in Systemic Lupus Erythematosus has been terminated.
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Effect of HCQ on AnxA5 Resistance Assay in Antiphospholipid (aPL) Positive Patients With and Without Systemic Lupus Erythematosus (SLE)
This completed trial assessed whether hydroxychloroquine affects AnxA5 resistance in antiphospholipid antibody–positive patients, with and w…
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: A Phase 1, Single-Ascending-Dose, Safety, Tolerability, Pharmacokinetic(PK), and Pharmacodynamic(PD) Study of BIIB068 in Healthy Participants [Phase 1]
This clinical trial update describes the completion of a Phase 1 single-ascending-dose study of BIIB068 in healthy participants, assessing s…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Safety and Efficacy of Adipose Derived Stem Cells in Refractory Rheumatoid Arthritis, Systemic Lupus Erythematosus or Sharp's Syndrome [Phase 1]
A Phase 1 trial evaluating adipose-derived stem cells for safety and efficacy in refractory rheumatoid arthritis, systemic lupus erythematos…
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Anti-ficolin-3 Autoantibodies in Lupus Nephritis
Clinical trial update on anti-ficolin-3 autoantibodies in lupus nephritis, a manifestation of systemic lupus erythematosus; the study status…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Anti-ficolin-2 Autoantibodies in Lupus Nephritis
A completed clinical trial investigated anti-ficolin-2 autoantibodies in patients with systemic lupus erythematosus, including lupus nephrit…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects [Phase 1]
Phase 1 dose-escalation study of an anti-C5aR antibody in healthy subjects has completed, reporting safety and pharmacokinetics data.
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: A Study of CD19 Redirected Autologous T Cells for CD19 Positive Systemic Lupus Erythematosus (SLE) [Phase 1]
A Phase 1 study evaluating CD19-directed autologous T cells for CD19-positive systemic lupus erythematosus (SLE) is being conducted; current…
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Autoimmunity in Sisters of Lupus Patients
A clinical trial investigating autoimmunity in sisters of patients with systemic lupus erythematosus has completed.
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: CHABLIS-SC1: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus [Phase 3]
Phase 3 trial evaluating subcutaneous blisibimod for systemic lupus erythematosus has completed; efficacy and safety results are not provide…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Health-Related Quality of Life in Patients With Systemic Lupus Erythematosus:Focusing on Fibromyalgia
This clinical trial update reports on health-related quality of life in patients with systemic lupus erythematosus, with a focus on fibromya…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: Individualized Patient Decision Making for Treatment Choices Among Minorities With Lupus [NA]
ClinicalTrials.gov study examining individualized treatment decisions for minority patients with systemic lupus erythematosus has completed,…