Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety and Efficacy of ONT01 in Lupus [EARLY_Phase 1]
ONT01 is in an early Phase 1 trial for lupus nephritis and systemic lupus erythematosus and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)
A completed clinical trial registry entry for patients with antiphospholipid syndrome and/or systemic lupus erythematosus, sponsored by Assi…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: 2-HOBA in Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial of 2-HOBA for systemic lupus erythematosus is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
A clinical trial is evaluating an educational tool to help melanoma patients with pre-existing autoimmune diseases who are candidates for im…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease [Phase 1]
Synthekine reports a Phase 1 study of SYNCAR-001 plus STK-009 without lymphodepletion in subjects with severe, refractory systemic autoimmun…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus [NA]
This clinical trial is currently recruiting participants for a study on childhood-onset systemic lupus erythematosus led by Michigan State U…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Quantum-Synaptic Immunotherapy Mapping Using Low-Frequency Electromagnetic Resonance and Machine Learning-Based Cytokine Forecasting [Phase 1, Phase 2]
This Phase 1/2 clinical trial update describes enrollment for a Quantum-Synaptic Immunotherapy approach that uses low-frequency electromagne…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity [NA]
This document provides an update on a rheumatology-focused clinical trial sponsored by Brigham and Women's Hospital that studies an adaptive…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases [Phase 2]
Phase 2 autologous stem cell transplantation trial for autoimmune diseases is currently recruiting, including systemic lupus erythematosus a…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Real World Evidence of Anifrolumab in Systemic Lupus Erythematosus: Investigator Initiated, Observational, Multicenter Study Evaluating Effectiveness and Safety of Anifrolumab in Active SLE Patients
Investigator-initiated, observational multicenter real-world study evaluating the effectiveness and safety of Anifrolumab in active systemic…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: European LUpuS Inception-Cohort Developing initiATivE
This clinical trial update describes a European inception-cohort study for systemic lupus erythematosus led by the University of Aarhus, whi…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. [EARLY_Phase 1]
Phase 1 study evaluating anti-CD19/BCMA universal CAR-T cell therapy RD06-05 in autoimmune diseases; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Comparative Autoantibody and Immunologic Cell Marker Study
This clinical trial update describes an ongoing study assessing autoantibody profiles and immune cell markers in autoimmune diseases, includ…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease [Phase 1, Phase 2]
Miltenyi Biomedicine is conducting Phase 1/2 trials of CAR-T cell therapy targeting B cells for autoimmune diseases, including systemic lupu…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Engagement in CHildhood-Onset Systemic Lupus [NA]
A clinical trial at Montefiore Medical Center is enrolling by invitation for childhood-onset systemic lupus erythematosus, with depression a…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update assessing a dual CD19/BCMA-targeted CAR T-cell therapy for relapse/refractory autoimmune diseases, currently r…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Mass Spectrometry-based Immune Profiling in Autoimmune Diseases
A clinical trial from Peking University People's Hospital evaluating mass spectrometry-based immune profiling across autoimmune diseases; th…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Development of a Dietary Intervention Model Based on Genetic Data as an Implementation of a Healthy Lifestyle in the Management of Systemic Lupus Erythematosus Patients [NA]
Protocol for developing a dietary intervention model based on genetic data to support healthy lifestyle management in systemic lupus erythem…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Centrally Acting ACE Inhibition in SLE [Phase 2]
Phase 2 clinical trial update on centrally acting ACE inhibition for Systemic Lupus Erythematosus; current status is ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Safety and Efficacy Study of CC312 for Moderate to Severe SLE [Phase 1]
Clinical trial update for a Phase 1 safety and efficacy study of CC312 in moderate to severe systemic lupus erythematosus, with recruitment …
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus [Phase 1]
Phase 1 clinical study evaluating A-319 for active or refractory systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of VIS171 in Participants With Autoimmune Disease(s) [Phase 1]
A Phase 1 clinical trial is evaluating the safety, tolerability, pharmacodynamics, pharmacokinetics, and immunogenicity of VIS171 in partici…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: LUpus Eritematoso Sistemico NETwork and Registry
An Italian clinical trials network and registry for systemic lupus erythematosus (SLE) that is currently not recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase exploratory study evaluating BZE2204 CAR-T cells targeting CD19/CD22/BCMA for relapsed or refractory autoimmune diseases, cur…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients [Phase 1]
A Phase 1 UC-MSC cell therapy trial for systemic lupus erythematosus is currently recruiting.