Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis [NA]
This ClinicalTrials.gov study evaluates therapeutic drug monitoring of mycophenolate mofetil in systemic lupus erythematosus and lupus nephr…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update on an allogeneic CD19/BCMA-targeted CAR-γδT cell therapy assessing safety and preliminary pharmacodynamics in …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases [EARLY_Phase 1]
An early phase 1 exploratory trial is assessing the safety and potential efficacy of anti-CD19/BCMA CAR-NK cell injections for refractory pe…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating the safety and activity of SAR448501/DR-0201 in patients with autoimmune rheumatic diseases, including sys…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus.
A clinical trial is investigating modifiable sleep-related factors in patients with systemic lupus erythematosus to identify potential targe…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: IASO-782 in Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial evaluating IASO-782 for systemic lupus erythematosus is not yet recruiting, according to the trial record.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease [Phase 1]
Phase 1 trial update for Prulacabtagene Leucel (Prula-cel) in autoimmune diseases, with enrollment by invitation ongoing across indications …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: The Anifrolumab PRIM Program
The document indicates that AstraZeneca's Anifrolumab PRIM Program for systemic lupus erythematosus is currently recruiting participants.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus [Phase 1]
This clinical trial update reports that CLN-978, a subcutaneously administered CD19-directed T cell engager, is being studied in subjects wi…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases
A clinico-biological collection study designed to investigate the pathophysiology of systemic autoimmune diseases, including systemic lupus …
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD) [Phase 1]
A Phase 1 clinical trial evaluating GSK5926371 in participants with B-cell driven autoimmune rheumatic diseases, including systemic lupus er…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Multicenter, Observational, Descriptive Study of the Diagnosis, Course and Treatment of Patients With SLE in Routine Practice in Kazakhstan: a Registry Study With Retrospective and Prospective Components.
A multicenter registry study in Kazakhstan to describe systemic lupus erythematosus activity, disease course, and treatment in routine pract…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis. [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD5492 in adults with systemic lupus erythem…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). [Phase 3]
Phase 3 extension study to evaluate long-term safety of ianalumab in systemic lupus erythematosus; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Moderate to Severe Active SLE Clinical Research [EARLY_Phase 1]
This early-phase trial investigates the safety and potential efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) for moderate to se…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases [NA]
A clinical trial evaluating EVM18001 for refractory autoimmune diseases is currently recruiting, including systemic lupus erythematosus, sys…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus [Phase 3]
Phase 3 clinical trial assessing adverse events and changes in disease activity with oral upadacitinib in adults with moderate to severe sys…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants [Phase 1]
Phase 1 clinical trial update for GSK4527363 including systemic lupus erythematosus and connective tissue disease-associated interstitial lu…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment [Phase 2]
This Phase 2 study is evaluating the efficacy and safety of induction therapy combining belimumab and telitacicept in proliferative lupus ne…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating anti-CD19 CAR-T cell therapy for refractory systemic lupus erythematosus, including lupus nephritis…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: COVID-19 Booster and IIV Schedule in Immunocompromised Hosts [Phase 2]
Phase 2 clinical trial from McGill University Health Centre evaluating a COVID-19 booster and influenza vaccine schedule in immunocompromise…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Study of GR1803 in Systemic Lupus Erythematosus [Phase 1, Phase 2]
Ongoing clinical trial update for GR1803 in systemic lupus erythematosus, spanning Phase 1 and Phase 2, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CT1190B in the Treatment of Patients With Moderate to Severe Refractory Systemic Lupus Erythematosus (SLE) or Refractory/Progressive Systemic Sclerosis (SSc) [Phase 1]
A Phase 1 study evaluating CT1190B for moderate-to-severe refractory systemic lupus erythematosus or refractory/progressive systemic scleros…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease [Phase 1]
Phase 1 study update for FT819 in B-cell–mediated autoimmune diseases; recruitment is ongoing for ANCA-associated vasculitis, idiopathic inf…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus [Phase 1]
Phase 1 safety study update for SG301-SC in systemic lupus erythematosus; the trial is currently active but not recruiting.