Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2018-05-11Clinical Trial Update: Fatigue, Depression, and Cortical Excitability in Systemic Lupus
An ongoing clinical trial from Assiut University investigates fatigue, depression, and cortical excitability in systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: Compassionate Use for Subcutaneous (SC) Belimumab
Compassionate-use program for subcutaneous belimumab in systemic lupus erythematosus has been updated; the program is no longer available.
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CLINICAL_TRIALS research · 2017-12-07Clinical Trial Update: Evaluation of Belimumab Impact on a BLyS Activity Signature Test in the Absence of Confounding Polypharmacy [Phase 4]
A Phase 4 clinical trial update evaluating belimumab's impact on a BLyS activity signature test in systemic lupus erythematosus, without con…
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CLINICAL_TRIALS research · 2017-11-21Clinical Trial Update: Scrutinizing the Heterogeneity of SLE: Defining Phenotypes
Clinical trial update focusing on defining phenotypes and heterogeneity within systemic lupus erythematosus to improve subtype characterizat…
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CLINICAL_TRIALS research · 2017-08-30Clinical Trial Update: CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
The CLUE study on the etiology of leg ulcers in connective tissue disease patients has completed, with the document noting completion and no…
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CLINICAL_TRIALS research · 2017-08-04Clinical Trial Update: The Impact of Illness Perceptions on Health Related Outcomes in Patients With Lupus and Systemic Sclerosis
Completed clinical trial evaluating how patients' illness perceptions relate to health-related outcomes in systemic lupus erythematosus and …
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Hormonal and Environmental Risk Factors for Developing Systemic Lupus Erythematosus: The Carolina Lupus (CLU) Study
A completed study evaluating hormonal and environmental risk factors for developing systemic lupus erythematosus in the Carolina Lupus (CLU)…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Disease Progression and Activity in Patients With Systemic Lupus Erythematosus
This clinical trial update summarizes disease progression and activity in patients with systemic lupus erythematosus; the NIEHS-funded study…
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CLINICAL_TRIALS research · 2017-06-14Clinical Trial Update: Long Non Coding RNA in Complications of Systemic Lupus [NA]
This entry documents a Cairo University-led clinical trial investigating the role of long non-coding RNA in complications of systemic lupus …
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CLINICAL_TRIALS research · 2017-05-31Clinical Trial Update: Systemic Lupus and Adverse Pregnancy Outcome
An update from a clinical trial at Beni-Suef University examining systemic lupus erythematosus and adverse pregnancy outcomes; the current t…
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CLINICAL_TRIALS research · 2017-03-20Clinical Trial Update: Autologous Stem Cell Transplantation for Refractory Systemic Lupus Erythematosus (ASSIST) [Phase 2]
Phase 2 clinical trial update investigating autologous stem cell transplantation for patients with refractory systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2016-09-23Clinical Trial Update: Study of the Role of Soluble Forms of RAGE (sRAGE/esRAGE) as Diagnostic and Prognostic Biomarkers of Systemic Lupus Erythematosus.
A clinical trial evaluating whether soluble forms of RAGE (sRAGE/esRAGE) can serve as diagnostic and prognostic biomarkers for systemic lupu…
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CLINICAL_TRIALS research · 2016-08-05Clinical Trial Update: Transcultural Validation in French of the Systemic Lupus Activity Questionnaire (SLAQ) and the Lupus Quality Of Life (LupusQoL) Questionnaire
This study reports the French transcultural validation of the Systemic Lupus Activity Questionnaire (SLAQ) and LupusQoL for patients with sy…
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Circulating MicroRNAs in Understanding Pathogenesis of Systemic Lupus Erythematosis [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/2 study examining circulating microRNAs in the pathogenesis of systemic lupus erythematosus.…
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CLINICAL_TRIALS research · 2015-12-14Clinical Trial Update: Magnetic Resonance Spectroscopy, Perfusion and Diffusion Tensor Imaging in Neuropsychiatric Lupus [NA]
A completed University of Michigan clinical trial evaluated MRI-based imaging techniques (MR spectroscopy, perfusion, and diffusion tensor i…
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CLINICAL_TRIALS research · 2015-11-17Clinical Trial Update: The CARRA Registry
The CARRA Registry study sponsored by Duke University has completed, documenting a broad range of juvenile rheumatic diseases, including Juv…
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CLINICAL_TRIALS research · 2015-06-08Clinical Trial Update: A Pilot-Study With Low-dose hrIL-2 for the Treatment of Systemic Lupus Erythematosus [Phase 2]
A Phase 2 pilot study is evaluating low-dose hrIL-2 for the treatment of Systemic Lupus Erythematosus, with the study status currently unkno…
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CLINICAL_TRIALS research · 2014-01-16Clinical Trial Update: Aerobic Exercise on Improving Sleep in Systemic Lupus Erythematosus. [NA]
A clinical trial is evaluating whether aerobic exercise improves sleep quality in people with systemic lupus erythematosus, with sleep disor…
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CLINICAL_TRIALS research · 2013-11-05Clinical Trial Update: Umbilical Cord Derived Mesenchymal Stem Cells Transplantation for Active and Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating umbilical cord-derived mesenchymal stem cell transplantation for active an…
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CLINICAL_TRIALS research · 2013-09-24Clinical Trial Update: Development and Evaluation of Modified Yoga in Systemic Lupus Erythematosus (SLE) [NA]
This entry reports on a completed clinical trial evaluating a modified yoga program for Systemic Lupus Erythematosus conducted by McGill Uni…
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CLINICAL_TRIALS research · 2013-05-29Clinical Trial Update: The Effect of Calcitriol on Progress and Activity of Lupus Nephritis [Phase 2]
Phase 2 clinical trial investigating calcitriol for progression and activity in lupus nephritis associated with systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2012-10-23Clinical Trial Update: Physical Exercise, Endothelial Function and Progenitor Endothelial Cells in Systemic Lupus Erythematosus Patients [NA]
This clinical trial update describes a study examining the effects of physical exercise on endothelial function and progenitor endothelial c…
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CLINICAL_TRIALS research · 2012-03-21Clinical Trial Update: Retrospective Analysis of the Safety and Efficacy of Hydroxychloroquine in Immune Thrombocytopenia
A retrospective analysis assessing the safety and efficacy of hydroxychloroquine in immune thrombocytopenia, including cases with systemic l…
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CLINICAL_TRIALS research · 2012-02-20Clinical Trial Update: Coping Skills Training (CST) for Children With Chronic Health Conditions [Phase 2]
This update notes the completion of a Phase 2 clinical trial of Coping Skills Training for children with chronic health conditions, includin…
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CLINICAL_TRIALS research · 2011-11-15Clinical Trial Update: Ultrasound Evaluation of Hands in Patients With Systemic Lupus Erythematosus
This clinical trial update describes a study evaluating ultrasound of the hands in patients with systemic lupus erythematosus, with rheumato…