Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Ultrasonic COmparison of Salivary Glands in Autoimmune Diseases (COUGAR)
Clinical trial COUGAR, sponsored by University Hospital, Brest, will evaluate ultrasonic comparisons of salivary glands across autoimmune di…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases [Phase 1, Phase 2]
A Phase 1/2 trial evaluating sequential BCMA/CD19 CAR-T cells for relapsed/refractory autoimmune diseases (including systemic lupus erythema…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: JY231 Injection for the Treatment of Active Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
This clinical trial entry notes a Phase 1/2 study evaluating JY231 Injection for active systemic lupus erythematosus (SLE), currently recrui…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial evaluating the safety, tolerability, and pharmacodynamics of KP104 in participants with thrombotic microangiopathy …
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Efficacy of Seluang Fish Oil (Rasbora Argyrotaenia) and Synbiotics Supplementation on CD4+CD25+ Foxp3+ T-regulator Cells, IL17/IL-10 Ratio, and Disease Activity in Systemic Lupus Erythematosus Patients [NA]
A clinical trial is evaluating whether Seluang fish oil and synbiotic supplementation affect immune markers and disease activity in systemic…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Synergetic B-cell Immunomodulation in SLE - 2nd Study. [Phase 3]
Phase 3 clinical trial update on a synergetic B-cell immunomodulation approach for systemic lupus erythematosus; the study is currently acti…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a fourth-generation CAR-T cell therapy targeting BCMA and CD19 for refractory systemic lupus erythemat…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Different Aspects and Etiologies of Gastointestinal Bleeding in Patients With Systemic Lupus Erythematosus
The trial investigates different aspects and etiologies of gastrointestinal bleeding in patients with systemic lupus erythematosus and is no…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Rare AutoImmune SElf-management Programme Development
This document reports a clinical trial development for a Rare Autoimmune Self-management Programme, currently recruiting across several auto…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Safety of Administering Isoniazid to SLE Patients to Prevent TB [Phase 2, Phase 3]
A clinical trial update evaluating the safety of administering isoniazid to patients with systemic lupus erythematosus to prevent tuberculos…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: Universal CAR-T Cells (BRL-301) in Refractory Systemic Lupus Erythematosus [NA]
This Clinical Trials entry reports on BRL-301 universal CAR-T cells being studied for refractory systemic lupus erythematosus, with recruitm…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE [Phase 1, Phase 2]
Clinical trial update for GR1603 in systemic lupus erythematosus (Phase 1/Phase 2) evaluating safety, tolerability, and pharmacokinetics.
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: Association Between Neuropathy and Some Autoantibodies in Systemic Lupus Erythematosus (SLE) Patients
The document describes a clinical trial investigating the association between neuropathy and certain autoantibodies in systemic lupus erythe…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity
This clinical trial update describes evaluating CXCL5 levels in patients with systemic lupus erythematosus and how they relate to disease ac…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: ROLE of PLATELETS in the PATHOPHYSIOLOGY of SYSTEMIC LUPUS
A recruiting clinical study evaluating the role of platelets in the pathophysiology of systemic lupus erythematosus. The study also presents…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Studying Non Alcoholic Fatty Liver Disease and Liver Fibrosis Among Systemic Lupus Erythematosus Patients at Assiut University Hospital
A clinical trial at Assiut University Hospital is examining nonalcoholic fatty liver disease and liver fibrosis in patients with systemic lu…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Interferon Pathway Activation in Monogenic and Nonmonogenic Forms of Pediatric SLE [NA]
A pediatric systemic lupus erythematosus trial evaluating interferon pathway activation in monogenic and nonmonogenic forms is currently rec…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: H-pylori Infection With Disease Activity in Systemic Lupus Erythematosus and Rheumatoid Arthritis
A clinical trial examining the relationship between Helicobacter pylori infection and disease activity in systemic lupus erythematosus and r…
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CLINICAL_TRIALS research · 2024-09-03Clinical Trial Update: Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases. [Phase 1]
Open-label Phase 1 study evaluating the safety and preliminary efficacy of combining Rituximab with AB-101 in B-cell–associated autoimmune d…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322)
An ongoing clinical trial investigating anti-C1s, anti-HMGB1, and anti-C1q autoantibodies as a treatment strategy for systemic lupus erythem…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: JWCAR201 for the Treatment of Hematology Malignancy and Autoimmune Diseases [Phase 1]
This clinical trial update outlines the Phase 1 study JWCAR201 for hematology malignancies and autoimmune diseases, which is currently not r…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Systemic Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of Orelabrutinib in adults with systemic lupus erythematosus; the study is cu…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Follow-up of the Systemic Lupus Erythematosus Cohort as Part of the Multidisciplinary Consultation at Brest CHRU
This clinical trial entry describes a follow-up cohort study on systemic lupus erythematosus at Brest CHRU, currently recruiting as part of …
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Integration of Remote Monitoring in the Management of Chronic Immunosuppressive Therapy [NA]
Clinical trial update on integrating remote monitoring into chronic immunosuppressive therapy for rheumatoid arthritis, psoriatic arthritis,…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Osteoporosis and Fragility Fractures Among SLE Patients. (FRAIL Trial)
The FRAIL Trial is studying osteoporosis and fragility fractures in patients with systemic lupus erythematosus and is currently active but n…