Systemic Juvenile Idiopathic Arthritis
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CLINICAL_TRIALS trial_result · 2026-08-11Clinical Trial Update: A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA) [Phase 3]
Phase 3 trial update for baricitinib in children aged 1 year to under 18 with systemic juvenile idiopathic arthritis (sJIA); study status is…
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CLINICAL_TRIALS trial_result · 2026-07-16Clinical Trial Update: A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA) [Phase 3]
Phase 3 trial investigating baricitinib (LY3009104) in children aged 1 year to under 18 with systemic juvenile idiopathic arthritis; status …
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE [Phase 3]
A Phase 3 clinical trial evaluated the efficacy, safety, tolerability, and pharmacokinetics/pharmacodynamics of emapalumab in children and a…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Assessment of Macrophage Activation syndromE in STill's Disease in Italy
A clinical trial evaluating macrophage activation syndrome in Still's disease (systemic juvenile idiopathic arthritis and adult-onset Still'…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA [Phase 3]
Phase 3 safety, efficacy, and pharmacokinetics study of tofacitinib in pediatric patients with systemic juvenile idiopathic arthritis has co…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Assessment of Macrophage Activation syndromE in STill's Disease
A completed clinical trial assessing macrophage activation syndrome in Still's disease, including adult-onset Still's disease and juvenile-o…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Long-term Safety Study of Kineret® in Patients With Systemic Juvenile Idiopathic Arthritis (SJIA)
This clinical trial update reports long-term safety data for anakinra (Kineret) in patients with systemic juvenile idiopathic arthritis (SJI…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: A Study of Tocilizumab in Chinese Participants With Systemic Juvenile Idiopathic Arthritis (sJIA) [Phase 4]
A Phase 4 clinical trial update evaluating tocilizumab in Chinese participants with systemic juvenile idiopathic arthritis has completed.
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic Arthritis [Phase 2]
Phase 2 open-label multicenter trial assessing safety and efficacy of ITF2357 in active systemic juvenile idiopathic arthritis has completed…
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: A Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 Studies [Phase 3]
Phase 3 trial update for canakinumab in systemic juvenile idiopathic arthritis and hereditary periodic fevers; results completed with postin…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: A Study of Decreased Dose Frequency in Participants With Systemic Juvenile Arthritis Who Experience Laboratory Abnormalities During Treatment With RoActemra/Actemra (Tocilizumab) [Phase 4]
Phase 4 study evaluating reduced dosing frequency of tocilizumab (RoActemra/Actemra) in pediatric patients with systemic juvenile idiopathic…
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CLINICAL_TRIALS trial_result · 2019-09-25Clinical Trial Update: Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis [Phase 3]
Phase 3 trial of etanercept (Enbrel) in children with systemic onset juvenile rheumatoid arthritis was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Study of Efficacy and Safety of Canakinumab in Japanese Patients With SJIA [Phase 3]
Phase 3 trial update on canakinumab for systemic juvenile idiopathic arthritis in Japanese patients; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-07-09Clinical Trial Update: ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab [Phase 3]
Phase 3 trial update for canakinumab in first-line use for systemic juvenile idiopathic arthritis (SJIA) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis [Phase 1]
This is a Phase 1 trial of subcutaneously administered tocilizumab for systemic juvenile idiopathic arthritis; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Single Patient Use of Tocilizumab in Systemic Onset Juvenile Idiopathic Arthritis [NA]
One-patient trial update describes the use of tocilizumab in systemic juvenile idiopathic arthritis. The trial was terminated and results we…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: An Open-label Extension Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis and Active Systemic Manifestations Manifestations and Response Characterization Study in Canakinumab Treatment-naïve Patients With Active SJIA With and Without Fever. [Phase 3]
Phase 3 trial update for canakinumab in systemic juvenile idiopathic arthritis, including an open-label extension and treatment-naïve cohort…
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young Adults [Phase 2]
Phase 2 trial evaluating the safety and effectiveness of Rilonacept for systemic juvenile idiopathic arthritis in children and young adults;…
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CLINICAL_TRIALS trial_result · 2013-03-04Clinical Trial Update: Study to Evaluate the Safety and Tolerability of Two Doses of Rilonacept in Pediatric Subjects With Active Systemic Juvenile Idiopathic Arthritis (SJIA) [Phase 1]
A Phase 1 study evaluating the safety and tolerability of two doses of rilonacept in pediatric patients with active systemic juvenile idiopa…
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CLINICAL_TRIALS trial_result · 2012-10-16Clinical Trial Update: Flare Prevention Study of Canakinumab in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA) [Phase 3]
This update reports the results of a Phase 3 study evaluating canakinumab for preventing flares in patients with active systemic juvenile id…
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CLINICAL_TRIALS trial_result · 2012-04-09Clinical Trial Update: Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA) [Phase 3]
A Phase 3 single-dose trial of canakinumab in active systemic juvenile idiopathic arthritis was terminated, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2011-10-26Clinical Trial Update: A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA) [Phase 3]
Phase 3 study of tocilizumab (RoActemra/Actemra) in active systemic juvenile idiopathic arthritis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: Safety, Efficacy and Pharmacokinetics of Subcutaneous ACZ885 in Patients With Systemic Juvenile Idiopathic Arthritis (SJIA) [Phase 1, Phase 2]
This completed Phase 1/2 study assessed the safety, efficacy and pharmacokinetics of subcutaneous ACZ885 (canakinumab) in patients with syst…
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CLINICAL_TRIALS trial_result · 2009-12-23Clinical Trial Update: Long-term Treatment Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA) [Phase 3]
This update notes the completion of a long-term Phase 3 study evaluating MRA for systemic juvenile idiopathic arthritis, sponsored by Chugai…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA) [Phase 3]
A Phase 3 trial of MRA for systemic juvenile idiopathic arthritis has completed.