Systemic Inflammatory Response Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Improving Health Outcomes With Kefir [NA]
A clinical trial is recruiting to study the effects of kefir on inflammatory response, type 2 diabetes, and cardiovascular outcomes.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ [NA]
A quality improvement clinical trial at AFHJ aims to implement a timely sepsis and septic shock management protocol in the emergency departm…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study
This completed observational study explored whether memory CD8+ T cell levels correlate with sepsis severity and mortality. It was single-ce…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome
A clinical trial is ongoing to identify determinants of vascular leakage in systemic inflammatory response syndrome; the study is currently …
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Modulation of Molecular Fingerprinting in Pediatric Sepsis
A pediatric clinical trial is recruiting to study modulation of molecular fingerprinting in systemic inflammatory response syndrome, potenti…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Conventional Ultrafiltration Versus Dilutional Ultrafiltration in Pediatric CPB Patients
A pediatric trial comparing conventional ultrafiltration versus dilutional ultrafiltration during cardiopulmonary bypass to address systemic…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG [Phase 1, Phase 2]
A clinical trial update for a Phase 1/Phase 2 study at Ain Shams University comparing dexmedetomidine and methylprednisolone to modulate inf…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
A clinical trial investigating rapid identification of microbial species and antibiotic resistance in emergency department patients with inf…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Initial Feasibility Study of the CycloPE® Device [NA]
This clinical trial update notes an initial feasibility study of the CycloPE device for sepsis-related conditions; the trial is currently ac…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure
This entry reports ongoing recruitment for a study evaluating extracorporeal blood purification therapy (EBPT) in critically ill patients wi…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients
A web-based multicenter registry is being developed to collect data on the use of the oXiris membrane for extracorporeal blood purification …
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT)
The GlobalARRT trial is evaluating extracorporeal blood purification therapy in critically ill patients. Recruitment is ongoing, including p…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating thymic tissue-derived regulatory T cells (thyTreg) to control immune hyperactivation in Systemic Infla…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI) [NA]
This document reports that the PANDA VI trial evaluating sivelestat for protection against negative pulmonary function and organ dysfunction…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) [Phase 2]
Phase 2 clinical trial evaluating perioperative blood management (PBM) as a strategy for patients with anemia undergoing coronary artery byp…
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome [Phase 2]
Phase 2 clinical trial update for MultiStem investigating treatment of trauma-induced multiple organ dysfunction syndrome and systemic infla…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock [Phase 4]
An ongoing Phase 4 clinical trial evaluating angiotensin-II as a second vasopressor for septic shock, currently recruiting.
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
This clinical trial update describes a study comparing systemic inflammatory response syndrome and sepsis in the context of aortic surgery. …
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis
This clinical trial update describes a study on applying biomarker changes to predict outcomes in patients with severe sepsis.
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CLINICAL_TRIALS research · 2017-02-06Clinical Trial Update: Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients [NA]
This clinical trial update investigates whether vitamin D supplementation affects hepcidin levels and transfusion requirements in surgical a…
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CLINICAL_TRIALS research · 2016-06-30Clinical Trial Update: The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the Mechanism
Clinical trial update exploring how the inflammatory response may predict success of ventilator weaning and the underlying mechanisms.
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CLINICAL_TRIALS research · 2014-10-30Clinical Trial Update: Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation. [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating stimulation of the cholinergic anti-inflammatory pathway to prevent and treat systemic inflammatory re…
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CLINICAL_TRIALS research · 2014-07-16Clinical Trial Update: Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial evaluating a single-dose alpha-1 antitrypsin to reduce organ injury in patients undergoing …
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CLINICAL_TRIALS research · 2014-06-13Clinical Trial Update: Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational Study
This clinical trial update describes a prospective observational study that assesses how common hypermetabolism is in the early phase of ICU…
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CLINICAL_TRIALS research · 2013-04-24Clinical Trial Update: Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in Sepsis
This clinical trial update describes investigating Alpha-1-acid glycoprotein as a biomarker for diagnosing and monitoring sepsis and systemi…